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Stem Cells, Cloning Bioethics

Why Bioethics? . . Current Bioethical Issues. Check the local news paperStem cells (state, national, international)Genetically Engineered OrganismsKnowing your genesIn vetro fertilization

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Stem Cells, Cloning Bioethics

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    1. Stem Cells, Cloning & Bioethics

    2. Why Bioethics?

    3. Current Bioethical Issues

    4. The First Bioethicist

    5. Limits on Freedom

    6. “The Commons”

    7. Technical Solutions

    8. Problems – Solutions? Another point that Hardin made was that many problems do not have a technical solution – these can range from Tick-tack-toe to disarmament to managing fish stocks and to many of the issues that our panelist will briefly discuss.Another point that Hardin made was that many problems do not have a technical solution – these can range from Tick-tack-toe to disarmament to managing fish stocks and to many of the issues that our panelist will briefly discuss.

    9. Bioethics

    10. Ethics and Science

    11. Ethics and Science

    12. Question??

    13. ELSI

    14. Topics

    15. Stem Cell History

    16. Importance

    17. DNA – T-A C-G

    18. Central Dogma of Molecular Biology

    19. Gene Expression

    20. Human Variability in DNA SNPs (single nucleotide polymorphisms) Many examples directly cause disease Huntington’s, Cystic Fibrosis, Muscular Dystrophy, etc. The ‘environment’ also plays a big role

    21. Common Cystic Fibrosis Mutation

    22. Parents to Children

    23. Gene Environment Interactions PKU and consumption of phenylalanine Malaria and Sickle Cell gene HIV infection and CCR5 receptor variant Alcohol intolerance and aldehyde dehydrogenase Beryllium disease (exposure to beryllium) Common variants, called polymorphisms, occur at greater than 1% frequency I have given some examples of how exposure induced risk is modified in various ways Typically the effects are modest in magnitude. We are interested in how genetics modifies Exposure and exposure-related diseases Because….. Common variants, called polymorphisms, occur at greater than 1% frequency I have given some examples of how exposure induced risk is modified in various ways Typically the effects are modest in magnitude. We are interested in how genetics modifies Exposure and exposure-related diseases Because…..

    24. Sexual Reproduction Every cell contains a complete copy of “the blueprint of life” DNA consists of two strands of nucleotides - 4 bases (A,G,T,C) 23 pairs of chromosomes If unwound and tied together, human DNA in one cell would stretch ~ 5 feet, but would be only 50 trillionths of an inch wide! Genes are specific sequences of DNA, each of which “codes” for a protein with a specific function Genes are copied each time a cell divides, passing on the blueprint Every cell contains a complete copy of “the blueprint of life” DNA consists of two strands of nucleotides - 4 bases (A,G,T,C) 23 pairs of chromosomes If unwound and tied together, human DNA in one cell would stretch ~ 5 feet, but would be only 50 trillionths of an inch wide! Genes are specific sequences of DNA, each of which “codes” for a protein with a specific function Genes are copied each time a cell divides, passing on the blueprint

    25. Stem Cell Differentiation

    26. Stem Cell Cultivation

    27. Embryonic Stem Cells (ESCs)

    28. Blastocyst Diagram

    29. Human Clones? Every cell contains a complete copy of “the blueprint of life” DNA consists of two strands of nucleotides - 4 bases (A,G,T,C) 23 pairs of chromosomes If unwound and tied together, human DNA in one cell would stretch ~ 5 feet, but would be only 50 trillionths of an inch wide! Genes are specific sequences of DNA, each of which “codes” for a protein with a specific function Genes are copied each time a cell divides, passing on the blueprint Every cell contains a complete copy of “the blueprint of life” DNA consists of two strands of nucleotides - 4 bases (A,G,T,C) 23 pairs of chromosomes If unwound and tied together, human DNA in one cell would stretch ~ 5 feet, but would be only 50 trillionths of an inch wide! Genes are specific sequences of DNA, each of which “codes” for a protein with a specific function Genes are copied each time a cell divides, passing on the blueprint

    30. Cloning Defined Every cell contains a complete copy of “the blueprint of life” DNA consists of two strands of nucleotides - 4 bases (A,G,T,C) 23 pairs of chromosomes If unwound and tied together, human DNA in one cell would stretch ~ 5 feet, but would be only 50 trillionths of an inch wide! Genes are specific sequences of DNA, each of which “codes” for a protein with a specific function Genes are copied each time a cell divides, passing on the blueprint Every cell contains a complete copy of “the blueprint of life” DNA consists of two strands of nucleotides - 4 bases (A,G,T,C) 23 pairs of chromosomes If unwound and tied together, human DNA in one cell would stretch ~ 5 feet, but would be only 50 trillionths of an inch wide! Genes are specific sequences of DNA, each of which “codes” for a protein with a specific function Genes are copied each time a cell divides, passing on the blueprint

    31. Asexual Reproduction Every cell contains a complete copy of “the blueprint of life” DNA consists of two strands of nucleotides - 4 bases (A,G,T,C) 23 pairs of chromosomes If unwound and tied together, human DNA in one cell would stretch ~ 5 feet, but would be only 50 trillionths of an inch wide! Genes are specific sequences of DNA, each of which “codes” for a protein with a specific function Genes are copied each time a cell divides, passing on the blueprint Every cell contains a complete copy of “the blueprint of life” DNA consists of two strands of nucleotides - 4 bases (A,G,T,C) 23 pairs of chromosomes If unwound and tied together, human DNA in one cell would stretch ~ 5 feet, but would be only 50 trillionths of an inch wide! Genes are specific sequences of DNA, each of which “codes” for a protein with a specific function Genes are copied each time a cell divides, passing on the blueprint

    32. Cloning Dolly Every cell contains a complete copy of “the blueprint of life” DNA consists of two strands of nucleotides - 4 bases (A,G,T,C) 23 pairs of chromosomes If unwound and tied together, human DNA in one cell would stretch ~ 5 feet, but would be only 50 trillionths of an inch wide! Genes are specific sequences of DNA, each of which “codes” for a protein with a specific function Genes are copied each time a cell divides, passing on the blueprint Every cell contains a complete copy of “the blueprint of life” DNA consists of two strands of nucleotides - 4 bases (A,G,T,C) 23 pairs of chromosomes If unwound and tied together, human DNA in one cell would stretch ~ 5 feet, but would be only 50 trillionths of an inch wide! Genes are specific sequences of DNA, each of which “codes” for a protein with a specific function Genes are copied each time a cell divides, passing on the blueprint

    33. Cloning A Sheep Every cell contains a complete copy of “the blueprint of life” DNA consists of two strands of nucleotides - 4 bases (A,G,T,C) 23 pairs of chromosomes If unwound and tied together, human DNA in one cell would stretch ~ 5 feet, but would be only 50 trillionths of an inch wide! Genes are specific sequences of DNA, each of which “codes” for a protein with a specific function Genes are copied each time a cell divides, passing on the blueprint Every cell contains a complete copy of “the blueprint of life” DNA consists of two strands of nucleotides - 4 bases (A,G,T,C) 23 pairs of chromosomes If unwound and tied together, human DNA in one cell would stretch ~ 5 feet, but would be only 50 trillionths of an inch wide! Genes are specific sequences of DNA, each of which “codes” for a protein with a specific function Genes are copied each time a cell divides, passing on the blueprint

    34. Human Stem Cell Production Every cell contains a complete copy of “the blueprint of life” DNA consists of two strands of nucleotides - 4 bases (A,G,T,C) 23 pairs of chromosomes If unwound and tied together, human DNA in one cell would stretch ~ 5 feet, but would be only 50 trillionths of an inch wide! Genes are specific sequences of DNA, each of which “codes” for a protein with a specific function Genes are copied each time a cell divides, passing on the blueprint Every cell contains a complete copy of “the blueprint of life” DNA consists of two strands of nucleotides - 4 bases (A,G,T,C) 23 pairs of chromosomes If unwound and tied together, human DNA in one cell would stretch ~ 5 feet, but would be only 50 trillionths of an inch wide! Genes are specific sequences of DNA, each of which “codes” for a protein with a specific function Genes are copied each time a cell divides, passing on the blueprint

    35. Removing Nucleus Every cell contains a complete copy of “the blueprint of life” DNA consists of two strands of nucleotides - 4 bases (A,G,T,C) 23 pairs of chromosomes If unwound and tied together, human DNA in one cell would stretch ~ 5 feet, but would be only 50 trillionths of an inch wide! Genes are specific sequences of DNA, each of which “codes” for a protein with a specific function Genes are copied each time a cell divides, passing on the blueprint Every cell contains a complete copy of “the blueprint of life” DNA consists of two strands of nucleotides - 4 bases (A,G,T,C) 23 pairs of chromosomes If unwound and tied together, human DNA in one cell would stretch ~ 5 feet, but would be only 50 trillionths of an inch wide! Genes are specific sequences of DNA, each of which “codes” for a protein with a specific function Genes are copied each time a cell divides, passing on the blueprint

    36. Nuclear transfer Every cell contains a complete copy of “the blueprint of life” DNA consists of two strands of nucleotides - 4 bases (A,G,T,C) 23 pairs of chromosomes If unwound and tied together, human DNA in one cell would stretch ~ 5 feet, but would be only 50 trillionths of an inch wide! Genes are specific sequences of DNA, each of which “codes” for a protein with a specific function Genes are copied each time a cell divides, passing on the blueprint Every cell contains a complete copy of “the blueprint of life” DNA consists of two strands of nucleotides - 4 bases (A,G,T,C) 23 pairs of chromosomes If unwound and tied together, human DNA in one cell would stretch ~ 5 feet, but would be only 50 trillionths of an inch wide! Genes are specific sequences of DNA, each of which “codes” for a protein with a specific function Genes are copied each time a cell divides, passing on the blueprint

    37. Coning for use in Stem Cells

    38. IVF – In Vitro Fertilization Every cell contains a complete copy of “the blueprint of life” DNA consists of two strands of nucleotides - 4 bases (A,G,T,C) 23 pairs of chromosomes If unwound and tied together, human DNA in one cell would stretch ~ 5 feet, but would be only 50 trillionths of an inch wide! Genes are specific sequences of DNA, each of which “codes” for a protein with a specific function Genes are copied each time a cell divides, passing on the blueprint Every cell contains a complete copy of “the blueprint of life” DNA consists of two strands of nucleotides - 4 bases (A,G,T,C) 23 pairs of chromosomes If unwound and tied together, human DNA in one cell would stretch ~ 5 feet, but would be only 50 trillionths of an inch wide! Genes are specific sequences of DNA, each of which “codes” for a protein with a specific function Genes are copied each time a cell divides, passing on the blueprint

    39. Stem Cells and Cloning

    40. Authorship Information

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