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Basics of Transfusion Therapy - PowerPoint PPT Presentation
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Basics of Transfusion Therapy. Laura Cooling MD, MS Associate Medical Director Transfusion Medicine. Blood Transfusion Policies and Standard Practices. www.pathology.med.umich.edu Select: Clinical Resource “Blood Bank and Transfusion Services” Link on UMHS Clinical Homepage.
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Blood Transfusion Policiesand Standard Practices
www.pathology.med.umich.edu
Select: Clinical Resource
“Blood Bank and Transfusion Services”
Link on UMHS Clinical Homepage
Blood Collection
- Most components results of single whole blood donations
- 500 mL blood + anticoagulant
- 20-30 min
- Blood processed into components
- packed RBC, FFP, platelets, cryo
- Manufactured Components: IVIgG, albumin, factor concentrates, etc….
Anticoagulants-Preservative
- Anticoagulant: Sodium citrate
- prevent coagulation through chelation Ca++
- Carbohydrate: Dextrose
- RBC utilize glycolytic pathway
- Buffer: Na Phosphate
- Counter lactic acid acumulation
- Adenine: Support ATP production
- Mannitol: Stabilize RBC membrane
DISTRIBUTION AND COMPATIBILITY
OF ABO TYPES AND BLOOD COMPONENTS
(holds true for solid organ transplant as well)
