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    1. Treatment in Common diseases 4th Pharmacy Students

    3. Upper respiratory tract infection (URI)

    5. ????????????????????????? ???????????????????????????????????????????????????????????????????? WHO ??????????????????????????????????????????????? ???????????????????????????????????? ?????? Acute Upper Respiratory Tract Infections (AURI) ???

    6. 1.???????????????????? ?????????????? (???? 2 ????? 5 ??)

    7. Acute upper respiratory tract infection (AURI) ??????????????????????????????????????????????????????????????????????? ????????????????? 4 ??????? 1. Common cold Acute rhinitis/ acute nasopharyngitis 2. Acute pharyngitis/ acutetonsillitis/ pharyngotonsillitis 3. Acute sinusitis 4. Acute otitis media

    8. 1. Common cold (??????????) ????????????????????????? ?????????????????????????????????? Otitis media, sinusitis ???????????????????? ??????: ?????????????????? ????????? ??? Rhinovirus ?????? 1/3 ????????????????? Coronavirus ?????? 10 ??????????????????????? ?????????: ???????????? ?????? ??????????????????????? ?????????????????

    9. 1. Common cold (???) ????????????????????????????????????? ???????? 3 ????? 3 ?? ????? ????????????????????????? 1-4 ??? ???????????????? ??? ?????????? ????????? ??????? ?????????????? ?? ??????? 1-2 ?????? * ????????????????????????????? ????????????? (post nasal drip) ??????????????????? ?????????????????, ??????? ????, ????????????? ???????????? ?????????????? 7-10 ??? ?????????????? 2-3 ??????? ?????????????????????????????????????????????????????????????? 2 ??????? ??????????????????????????? ???????? sinusitis ??????????? ???????????: ???????????? ???????? ?????????????????????? ??????

    10. 1. Common cold (???) ????????: ????????????????????????????????? 1.?????????????: ??????????????? ??????????????????????????? ??????????? ????? ????????????????? 2.?????????????: ????? ???????? paracetamol ????????????? ????????? aspirin ???????????? Reye syndrome ?????????????????????????? ???? Influenza virus

    11. ????????????????????????????? ?????????????????? ?????????????? ???????????/NSS ?????????????????????????????????? ?????????????????????????????????? ????????????????????????????????? ephredine, phenylephrine ???????????????????????????????? 3-5 ??? ???????????????????????????????????????? ????? ????????????? ammonium carbonate ???? glyceryl guaiacolate ?????????????????????????????????????????????????? ?????????????????????? ?????????????????????????????????? 1. Common cold (???)

    12. 3. ???????????????????????????? - ???????????? 3 ??? ????????????, ??? - ????????????????, wheezing - ????????????????? 30 ??? 1. Common cold (???)

    13. 2. Influenza (???????????) ??????????????????? Influenza (type A,B,C) ????????????????? 1-3 ??? ?????????????????????????????? ???????? ??????????? ????????? ??????????????? ???????????? ??????????????????????? ?????????????????????? ???????????? ????????????? ??????? ????????????????? 3-4 ????????????? ???????????????????

    14. 3.Acute pharyngitis/ acutetonsillitis/pharyngotonsillitis ?????????????? pharynx ???/???? tonsil ???????????????????? ?????????????????: adenovirus, herpes simplex, echo virus ??????? ????????? Group A beta hemolytic streptococcus, C. diptheria (??????) ??????????????????? 6 ?????

    15. Viral pharyngitis ?????? ???????? ?????????????????????? ???????????????????? ???????????????? Coxakievirus ???????/?????????? pharynx, tonsil ????????????? 3.Acute pharyngitis/acutetonsillitis/ pharyngotonsillitis (???)

    16. Streptococcal pharyngitis/sore throat Beta-hemolytic streptococcus group A (S. pyrogens) ??????????????????? 2 ???????? ?????? ????????? ?????????????? ????????????????????????? ????????, tonsil ???????????? 2 ???? ????? exudate ??????????????????????????? ?????????????? Penicillin V 5 ??? 1 ???? ?????/??./??? ???????? 10 ??? ???? Amoxycllin 40-50 ??./??./??? ???????? 10 ??? ???? Benzathine penicillin IM ?????????? 6 ??? ??????????????????? 5 ?? ?????????????? 5 ????? 1.2 ???? ????? Erythromycin 30-50 ??./??./??? ???????? 10 ??? 3.Acute pharyngitis/ acutetonsillitis/ pharyngotonsillitis (???)

    18. 4.Acute sinusitis ??????????????????????????? ???? ?????????????????????????????????? ???????? ???????????????? maxillary ??? ethmoid sinus ???????????????????????? ???? 3-5 ?? ????????????? sphenoid ??? frontal sinus ??????????? S. pneumoniae, M.catarrhalis Nontypable H. influenza

    19. ????????????????? ???????????????????????????? ??????????????????????: ??????, ???????????????? ??????????????????, ????????????, ???????????????????????????? ?????? ???????????????, ??????????????????????, ??????????????????????????? ????????: ????????????? Amoxycillin ??? 10-14 ??? ??????? penicillin ??? TMP-SMX + erythromycin ??? 10-14 ??? ??????????????????? 48 ??. ??????????????????????????????? ?????? 2nd ???? 3rd generation cephalosporin ??? 14-21 ??? antihistamine ??? decongestant ????????????????????????? ????????????????????? sinus drainage

    22. ?????????????????????????????????????????? (middle ear effusion) ??????????????????????????????????????????????????? ???????????????????????????? eustachain ???????????????????????????? 10 ???? (??????? 45 ????) ???????????: ?????, ????????? S. pneumoniae ?????? 35 H. influenza ?????? 30 M. catarrhalis ?????? 10 5.Acute otitis media (AOM)

    25. ????????????????? ?????????? ????????????????????????????? ???????????????????????? ????????????????? ?????????????????? 2 ??????? ?????????????? chronic otitis media ???????? ?????????? Amoxycillin 40-50 ??./??./??????????? 7 ??? ??? penicillin ??? TMP 6-10 ??./??./??? ??? cotrimoxazole ???? erythromycin 20-40 ??./??./??? ???????? 7 ??? ????????????????? 2 ??, ?????????????, ???????????, ?????????????? ?????? 2nd ???? 3rd generation cephalosporin antihistamine ??? decongestant ???????????????? 5. Acute otitis media (???)

    27. Lower respiratory tract infection (LRI) ???????????????????????????? upper airway obstruction (croup syndrome ???? infectious croup) Acute epiglotitis Acute laryngitis Acute laryngotracheobronchitis (croup) Laryngeal diptheria Bacterial tracheitis ???????????????????????????? lower airway obstruction Acute bronchitis, Acute bronchiolitis, Pneumonia

    28. 1. Acute laryngotracheobronchitis (croup) ?????????????????????????? 3 ????? - 3 ?? ??????????????????????? ???????? viral croup Parainfluenza virus Influenza A, B, Adenovirus ????????????????????????????????????? S. aureus, H. influenza

    29. ????????????????? ??????????????? ?????????????????????? ??????????? ????? ???????????????????????????????????????? ?????????? ??????????????? (stridor) ????????????????? (cyanosis) ???????????????????? ???????????????????????????????? 1. Acute laryngotracheobronchitis (croup) ???

    30. Asthma in children ?????? ????????????????????????????????????? ??????????????????????????????????????????????? ?????????????????????????????????????????????????? ???????????? ??????????? (atopy) ??????????????????? ?????????????????????? (allergens) ??????????? ????, ??????, ???????, ???????, ?????????, ??????? ??????? ???????????????????????????? (passive smoking) ??????????????????, ?????????????????????????????? ????????, ?????????? ?????????????? ?????????????????????? ????????? ???????????????????????????????? (?????)

    31. ???????????????????? ????????????????????? ??????????????????????????????????, ???????? ????????????????????????????????? ?????????????? ???????????????????????? ?????????????????????? ????????????????????????????? ?????????????????????????? ???????????????????????? ?????????????? ????????????????????????? ??????????????????????????????????????????? Asthma in children

    32. ??????????????? (?????) ???????? 1 ?????????????????????????????? (quick relief medication) Short acting beta2 agonist (inhale, oral) Inhaled anticholinergics Short acting theophylline ???????? 2 ???????????????? (long term prevention medication) Inhaled corticosteroid Long acting beta2 agonist Sustain release theophylline leukotriene receptor antagonist Sodium cromoglycate Ketotifen ??????????????????????????????????????????????????? (?????) Asthma in children

    33. Common skin diseases in children

    34. Topics 1. ???????????????????? (atopic dermatitis) 2. ??????????????????????????? (Bacterial skin infection) 3. ??????????????????????? (Viral skin infection) 4. ?????????????????? Tenia vescicolor ?????????? (Contact dermatitis) Common skin diseases in children

    35. ???????????????????? (atopic dermatitis) Atopic dermatitis (AD)???? Atopic eczema ??? ??????????????????????????????????????? ???? ?????????? ?????????????? ????????????????????????????????????????? ? ??????????????????????????????????????? ??????: ????????????? ??????????????????????????????????????????????????? ?????? ?????????????????? ????????? ???????????????????????????????????????? ???? ????? ????????? ??? ??????? ????????????? ???? ???????? ?????? ?????? ???? ???????? ??????????? ?????? ?????????????? ????????????????????? ?????????????? ??????????????????????????????? ????????????? ???? ???? ?????? ????????? ???????

    37. ????????????????????????????? Infantile atopic dermatitis ??????????? ??????????? acute ??? subacute ???????????????? ????????????? ??????????????????????????? 2 ??????????? ?????????????????????????????????????? ?????????? 6 ????? ??????????????????????? ??????? ?????????????????? ?????????????????????????????? 2-3 ?? Childhood atopic dermatitis ?????????? 2-3 ???????? ???????????????????????????????? ?????????????????? ????? ???????????? ????????????????????? ?????? ????? ??????????? ???????????????????????????? ??????????????????????????? Adolescent or adult atopic dermatitis ????????? childhood type ?????????????? hand eczema, nipple eczema, cheilitis (??????????????) 1. ???????????????????? (atopic dermatitis) ???

    38. Atopic dermatitis

    39. ???????????????????????????????????? ????????????????? ?????????????????????????????? 2 ?? ????????????????????? ??????????????? ????????????????? ???? ????????? 6 ????? ?????????????????????????????????????????????????? 1. ???????????????????? (atopic dermatitis) ???

    40. ????????: ???????????(?????) ??????????????????? (conventional therapy) ????????????????????????? Emollients: cream ointment oil ????????????????????????????? ???? ??????????? ???????????? ???? ???? ??? ??????? ?????????????????????????????????? ???????????????????????????? ????????????????????? Topical corticosteroid ???????????? ???????????????????????????????????????????????????? Systemic corticosteroid ?????????????????????? 2 ??????? Immunomodulation: cyclosporin, topial tacrolimus ??????? 1. ???????????????????? (atopic dermatitis) ???

    41. 2. ??????????????????????????? (Bacterial skin infection) ???????????? ??? 2.1 Impetigo contagiosum 2.2 Bullous impetigo 2.3 Staphylococcus scalded syndrome 2.4 Ecthyma 2.5 Furuncle 2.6 Erysipelas

    42. Impetigo contagiosum ?????????????????????????????????????????????? ??????? stratum croneum ??????? - 5 ?? ????????? (macule) ? ??????? (papule) ? ?????? (vesicle) ? ???? (pustule) ????????????????? ?????? S. aureus (80%) Beta-hemolytic streptococcus group A.

    43. ???????? Cloxacillin, erythromycin, cotrimoxazole, cephalosporin ??? 10-14 ??? ?????? ??? antihistamine ???????? ????????????????????? ???????? ????????????? ???????????????? NSS ??????????????????? ????? 3-4 ????? ????????????????????????????? 2-5 ??? ????????????????????????????????? ?????????? Impetigo contagiosum (???)

    44. Impetigo contagiosum (???)

    45. 3. ??????????????????????? (Viral skin infection) (sheet) 3.1 Hand, foot and mouth disease 3.2 Herpangina 3.3 Measles (??????) 3.4 Rubella (?????????????) 3.5Roseola infantum(?????????) 3.6 Molluscum contagiosum 3.7 Verruca vulgaris 3.8 Chikungunya infection 3.9 Dengue infection 3.10 Herpes simplex infection 3.11 Herpes zoster infection 3.12 HIV infection

    46. 3.1 Hand, foot and mouth disease ???????????????????????????? Coxackievirus A 16 ?????? 3-6 ??? ???????? 1-5 ?? ????? ????????????? ?????????????? ????? ??????????????? ????????????????? ???????????????????? ??????????????????? ??????? ????????????????? ?????????????????????????? ????????? ?????????????????????? ??????????????????????????

    47. 3.1 Hand, foot and mouth disease

    48. ???????????????????????????????????? Herpangina ?????????? ????????????????????? ??????? ?????????????????????? ????????? ????????????????? ?????????? ???????? ??????????????????? ???????, antihistamine ??????? sedative Prednisolone ???????????????, Xylocain viscous ????????? ?????? ?????? ???????????????????? 3-5 ??? 3.1 Hand, foot and mouth disease

    49. 3.2 Herpangina Coxackievirus A 2, 3, 4, 5, 6, 8, 10 ???????? 1-7 ?? ????????????????????????????? ????????? ??????? ???????????? ?????????????? ???? 1-2 mm ???? ??????????? ????????????????? ?????????? ??????? ????????? ???????? ????????????????????????? Hand, foot and mouth disease

    50. 3.2 Herpangina

    51. 4.????????????????? 4.1 Angular cheilitis (???????????) 4.2 Miliatria (??????) 4.3 Diaper dermatitis (???????????)

    52. 4.1 Angular cheilitis (???????????) ?????????????????? ??????? 2-10 ?? ??????????????????????????????? ????????? 2 ???? ???????????? ?????????????? ? ?????????????? ? ??????????????????????? ? ????????????????? ?????????????? ?????????????????? ????????????? ????????????????? Candida albicans, S.aureus, Beta hemolytic streptococcus Riboflavin deficiency ???????????????????????????

    53. 4.1 Angular cheilitis (???????????) ??? ???????? Mild topical corticosteroids Candida sp. ? Nystatin, miconazole, clotrimazole ????????????????????? 10 ???

    54. 4.2 Miliaria (??????) ??????????????????????????? ??????? ?????? ?????? ?????? ????? ????? ???????????????????? ?????????? ?????????????????? ????? ????????????????????????????????? ? ????????????? ?????????????????????? ??????????????????????????? S. epidermidis ???????? ???????????????? ??????????????????? Mild topical corticosteroids

    55. 4.2 Miliaria (??????)

    56. 4.3 Diaper dermatitis (???????????) ???? 9-12 ????? ???????? irritant contact dermatitis ????????????????????? ????????????????? ?????????????????????????????????? ???????????????????????? ??? ?????????????????? ???????????????????????? ??????????????????? ????????????????????????? ??????????? ?????????? ????????? ??????? ???????????????????????? ??????????? ???????????????????????? ?????????????????????????????? ???????????????????????

    57. 4.3 Diaper dermatitis (???????????)

    58. ??????????????????????????? ???????? ???????????? ??????????????????? ????????????? ??????????? Candida albicans ??????????? 3 ???????????????????? S.aureus, Streptococcus sp., E. coli ???????? Mild to moderate topical corticosteroids ?? 3-4 ??? ???????????? ????????????? ? Nystatin, miconazole, clotrimazole ??????????????? ?????? 10 ??? ???????????????????? ? ????????????????????????? ???????????????? ??????? 4.3 Diaper dermatitis (???????????) ???

    59. THE END