Differing Demographics of Vascular Parkinsonism and Idiopathic Parkinson’s Disease. Karthik Sarma MD Resident PGY4 Shreyansh Shah MD and William Ondo MD Dept of Neurology. 14 th April, 2011. 63rd AAN Annual Meeting, Hawaii, 2011. Disclosures. Anand K Sarma, MD Shreyansh D Shah, MD
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Karthik Sarma MD
Shreyansh Shah MD and William Ondo MD
Dept of Neurology
14th April, 2011
63rd AAN Annual Meeting, Hawaii, 2011.
W. Ondo: Grant Support: Ipsen, Acadia, Bayer, Takeda, Allergan, PSG, HSG, IMPAX
Speaking / Consulting fees: GSK, Allergan, Novartis, Ipsen, TEVA, UCB Pharma, Merz, Lundbeck
Source: BCM imaging database
AGE α RISK of PD
Age- and sex-specific average annual incidence rates (per 100,000 person-years) of parkinsonism and its types: Olmsted County, MN, 1976–1990*
Incidence and distribution of parkinsonism in Olmsted County, Minnesota, 1976-1990.
Bower JH, Maraganore DM, McDonnell SK, Rocca WA.
Neurology. 1999 Apr 12;52(6):1214-20.
Does the misdiagnosis of VP as PD increase the age of onset of PD in epidemiologic studies?
VP misdiagnosed as PD would cause the average age at symptom onset of PD to increase, altering the age related distribution of PD and hence the epidemiology of PD.
The incidence of PD in the population follows a bell shaped (normal) distribution about a median age of 60 years.
*- using Mann Whitney U test
* Chi Square test
Vascular Risk Factors
Age Groups in years
Age Groups in years
Does VP misdiagnosed as PD increase the average age at onset of PD?
57.81 to 59.36
[ 73.59 * 805 / 7742 ] + [ 57.81 * 6937 / 7742 ]
Proportional weighting based on relative occurrence
I would like to thank my friend and colleague, Yogeshwar V Kalkonde for his valuable input and help.
Questions? for “PD”…
View of Waikiki sunset from my room.
Karthik Sarma; 9th April, 2011.