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A. B. 200. fMLF. WKYMVM. 100. fMLF. 100 nM. WKYMVM. 100 nM. 80. 150. Maximum O 2 - production (% control). 60. O 2 - production (Mcpm). 100. 40. 20 nM. 20 nM. 50. 20. 0. 0. 0. 0. 6. 2. 4. 2. 4. 1. 10. 100. 1000. Time (min). Time (min).

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Fmlf

A

B

200

fMLF

WKYMVM

100

fMLF

100 nM

WKYMVM

100 nM

80

150

Maximum O2- production (% control)

60

O2- production (Mcpm)

100

40

20 nM

20 nM

50

20

0

0

0

0

6

2

4

2

4

1

10

100

1000

Time (min)

Time (min)

Agonist concentration (nM)

D

C

80

120

fMLF

WKYMVM

fMLF

WKYMVM

PMA

80

60

40

90

20

0

0

2

4

40

O2- production (% control )

O2- production (Mcpm)

Control

PTX (1.5h)

PTX (2h)

Control

PTX (1.5h)

PTX (2h)

60

30

0

0

0

2

4

0

2

4

6

0.01

0.1

1

5

Time (min)

Time (min)

PBP10 concentration (M )

Control

(2h)

PTX (2h)


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