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Advancing Oklahoma’s Knowledge Economy for the Next 100 Years

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  1. Advancing Oklahoma’s Knowledge Economy for the Next 100 Years

  2. OCAST ROI 1987 – FY2008 $165.4M $3.05B (State Funding) (Private & Federal) ROI = 18.47 Advancing Oklahoma’s Knowledge Economy for the Next 100 Years

  3. HEALTH RESEARCH • On average 25% of Health projects are funded • Approximately 100-150 applications are submitted each competition • Approximately $2 million is allocated for FY09 competition Advancing Oklahoma’s Knowledge Economy for the Next 100 Years

  4. Program Purpose • Provides seed funding to superior research projects conducted by Oklahoma-based investigators for the multiple purposes of: • Enhancing the competitiveness of Oklahoma health researchers for national research funds, • Recruiting and retaining outstanding health research scientists for the State, • Improving health care for Oklahoma citizens and • Strengthening the State's health care industry. Advancing Oklahoma’s Knowledge Economy for the Next 100 Years

  5. Program Description OCAST awards competitive health research funds, through: • Professional service contracts, • Public and private colleges and universities in Oklahoma, • Nonprofit health research organizations in the State and • Private enterprises of special importance to the Oklahoma economy. Advancing Oklahoma’s Knowledge Economy for the Next 100 Years

  6. Program Description • Research funded under this program investigates: • Causes • Diagnosis • Treatment and prevention of human diseases and disabilities • Facilitates the development of health care products and services. Advancing Oklahoma’s Knowledge Economy for the Next 100 Years

  7. Award Types • HR Scientist Recruitment and Retention: • $10,000 minimum budget for each year • $100,000 each year up to three years • Regular Oklahoma Health Research: • $10,000 minimum budget for each year • $45,000 maximum each year up to three years Advancing Oklahoma’s Knowledge Economy for the Next 100 Years

  8. Award Types • Regular & New Scientist Health Research Awards: • Funding awards are made on a year-by-year basis. • Neither approval of a multiple-year award nor funding of any year of a contract shall automatically lead to funding in subsequent years. • For each year originally awarded, funding shall be dependent on a satisfactory annual performance evaluation and the availability of funds. Advancing Oklahoma’s Knowledge Economy for the Next 100 Years

  9. ORGANIZATION ELIGIBILITY • Oklahoma public or private colleges and universities; • Oklahoma non-profit research organizations; • Oklahoma enterprises of special importance to the Oklahoma economy. • Enterprise defined as a firm with its principal place of business in Oklahoma. • . Advancing Oklahoma’s Knowledge Economy for the Next 100 Years

  10. APPLICANT ELIGIBILITY • Regular Oklahoma Health Research: • Is employed by, or affiliated with, an eligible applicant organization; • Holds at least the rank of assistant professor if at a college or university, or • Is equivalent in education and experience, as certified by the Chief Executive Officer of the applicant organization. Advancing Oklahoma’s Knowledge Economy for the Next 100 Years

  11. APPLICANT ELIGIBILITY • HR Scientist Recruitment and Retention: • These awards support the research projects of health research scientists who have previously not held a tenure track/or equivalent appointment at an Oklahoma institution • is employed by, or affiliated with, an eligible applicant organization; • holds at least the rank of assistant professor if at a college or university, or its equivalent in education and experience, as certified by the Chief Executive Officer of the applicant organization; and • submits an application within four years of accepting employment, or becoming affiliated with, the applicant organization. • Eligibility for the New Scientist Recruitment and Retention Program requires that a researcher must have not held a tenure track or equivalent appointment at an Oklahoma institution as a researcher before February 18, 2005. • . Advancing Oklahoma’s Knowledge Economy for the Next 100 Years

  12. APPLICANT ELIGIBILITY • HR Scientist Recruitment and Retention: • All applicants to the Health Research Scientist Recruitment program MUST ALSO MAKE APPLICATION TO THE Regular Health Research Program. • Do not submit two separate applications but include a research plan and budget forms for the Regular Health Research project in Appendix II in the Health Research Scientist Recruitment and Recruitment application. • . Advancing Oklahoma’s Knowledge Economy for the Next 100 Years

  13. APPLICANT ELIGIBILITY • HR Scientist Recruitment and Retention: • All applicants must meet all requirements for the Regular Research Program. • ANY HEALTH RESEARCH SCIENTIST RECRUITMENT AND RETENTION APPLICATION WITHOUT A RESEARCH PLAN AND BUDGET FORMS FOR THE REGULAR HEALTH RESEARCH PROJECT WILL BE RETURNED WITHOUT REVIEW FOR EITHER PROGRAM. • . Advancing Oklahoma’s Knowledge Economy for the Next 100 Years

  14. PREVIOUS RECIPIENT ELIGIBILITY • OCAST requires previous recipients of Oklahoma Health Research contracts to demonstrate evidence of submission to a national funding organization prior to submission of a new application for funding. • OCAST informs reviewers regarding satisfactory or unsatisfactory performance on previous OCAST contracts. • . Advancing Oklahoma’s Knowledge Economy for the Next 100 Years

  15. PREVIOUS RECIPIENT ELIGIBILITY • An individual PI may hold only one Oklahoma Health Research Contract at a time • A currently funded PI may compete with a new project, and, if successful, decline the current award to accept the new award. • A currently funded PI may also apply if the current project funding ends prior to the beginning of funding of a new FY09 award. • . Advancing Oklahoma’s Knowledge Economy for the Next 100 Years

  16. CHANGE OF PRINCIPAL INVESTIGATOR (P.I.) • If the PI of a proposed project becomes unable to perform the proposed research between submission of the application and the initial contract period, OCAST will not allow a change in PI. • Consequently, if the original PI ceases to head the project between submission and review, the project will not be eligible for review. • If the original PI is lost to the project prior to award, the project will not be considered for award. • When a PI on a proposed project becomes unable to perform, the applicant organization(s) must inform OCAST within ten (10) days. If funds have been awarded, monies will revert to the Oklahoma Health Research fund. • . Advancing Oklahoma’s Knowledge Economy for the Next 100 Years

  17. DELINQUENT REPORTS • Any PI, who has a delinquent progress report or has not responded to other OCAST requests for information, impact survey data, or special reports on a previously funded OCAST project, will not be eligible to submit an application for new project funding. • Any PI, who has a delinquent progress report at the time of review, will not be eligible for review. • Any PI with a delinquent progress report at the time of award will not receive a contract until the progress report has been submitted. In the latter case, if the delinquent report has not been submitted within sixty (60) days of the award date, OCAST will nullify the award and return the monies to the Oklahoma Health Research Fund. • . Advancing Oklahoma’s Knowledge Economy for the Next 100 Years

  18. Standards &Requirements Advancing Oklahoma’s Knowledge Economy for the Next 100 Years

  19. Solicitation Forms • Statement of Intent • & • Application • Editable forms can be found online at: • www.ocast.state.ok.us Advancing Oklahoma’s Knowledge Economy for the Next 100 Years

  20. SUBMISSION REQUIREMENTS • Statement of Intent • Deadline: • 5:00 P.M., February 4, 2009 • Delivery Method: • By mail or fax to (405) 319-8426 • Intents will NOT be accepted by email Advancing Oklahoma’s Knowledge Economy for the Next 100 Years

  21. SUBMISSION REQUIREMENTS • Applications • Deadline: • 5:00 P.M., February 18, 2009 • Delivery Method: • by mail or hand delivered only • No email or faxed applications Advancing Oklahoma’s Knowledge Economy for the Next 100 Years

  22. NO EXCEPTIONS STATEMENT OF INTENTS OR APPLICATIONS WILL NOT BE ACCEPTED AFTER THE DEADLINES… Advancing Oklahoma’s Knowledge Economy for the Next 100 Years

  23. Required Materials Each Health Research application must include the following materials: Advancing Oklahoma’s Knowledge Economy for the Next 100 Years

  24. Required Materials • 8 ½ x 11-inch white paper • Not less than 0.5-inch margins • Single to 1.5 spacing • Font size not smaller than 10-pt • Fonts must be Arial, Helvetica, Platino, Computer Modern, or Georgia • Use the presentation order and headings as shown Advancing Oklahoma’s Knowledge Economy for the Next 100 Years

  25. Required Materials • Total section text page length includes • Text • Inserted graphs • Charts • Figures • If not applicable, acknowledge by number the number and title by: • “Not Applicable” Advancing Oklahoma’s Knowledge Economy for the Next 100 Years

  26. Required Materials • Do not use • Binders • Notebooks • Rubber bands • Regular paper clips • OCAST recommends colored sheets to set-off major sections of the proposal • Do NOT type text on colored sheets. Advancing Oklahoma’s Knowledge Economy for the Next 100 Years

  27. ADDITIONAL REQUIREMENTS • Refer to the solicitation for the following: • IRB • Biographical information • Letters of recommendation • OCAST previous and other support • Facilities, instrumentation and resources Advancing Oklahoma’s Knowledge Economy for the Next 100 Years

  28. RESUBMISSIONS • A resubmission is a new proposal, which includes the information below: • A current Statement of Intent is required • Indicate it is a resubmission in Item 4 • Prepare an Appendix III that includes: • a letter responding to the reviewers’ comments from the previous review and noting all changes in the research plan, • a copy of the previously submitted application and • all reviews of that application. Advancing Oklahoma’s Knowledge Economy for the Next 100 Years

  29. RELEASE OF INFORMATION OCAST is subject to the Open Meetings Act and the Open Records Act. Statement of Intent, application abstracts and executive summaries from progress reports are consider public information. HOWEVER: marketing plans, financial statements, trade secrets, research concepts, methods or products, or any other proprietary information are exempt by statute. Advancing Oklahoma’s Knowledge Economy for the Next 100 Years

  30. Review Process &Evaluation Criteria Advancing Oklahoma’s Knowledge Economy for the Next 100 Years

  31. Board Acts on Reviewer Recommendations. Panels meet for final ranking of proposals. Panels meet in Oklahoma to evaluate and to rank proposals. Panels meet in Oklahoma to evaluate and to rank proposals. Proposals are sent to primary and secondary reviewers and all panel members. HR Committee assigns reviewers and builds panels. Compliance Checked

  32. EVALUATION CRITERIA (Compare to NIH) • In general, in addition to evaluating the appropriateness of the budget, peer reviewers evaluate applications for scientific merit according to the following criteria: • Significance • Approach • Innovation • Investigators • Environment • and Overall Evaluation Advancing Oklahoma’s Knowledge Economy for the Next 100 Years

  33. EVALUATION CRITERIA (Compare to NIH) Significance Does this study address an important problem? If the aims of the application are achieved, how will scientific knowledge or clinical practice be advanced? What will be the effect of these studies on the concepts, methods, technologies, treatments, services, or preventative interventions that drive this field? Advancing Oklahoma’s Knowledge Economy for the Next 100 Years

  34. EVALUATION CRITERIA (Compare to NIH) Approach Are the conceptual or clinical framework, design, methods, and analyses adequately developed, well integrated, well reasoned, and appropriate to the aims of the project? Does the applicant acknowledge potential problem areas and consider alternative tactics? Advancing Oklahoma’s Knowledge Economy for the Next 100 Years

  35. EVALUATION CRITERIA (Compare to NIH) Innovation Is the project original and innovative? For example: Does the project challenge existing paradigms or clinical practice; address an innovative hypothesis or critical barrier to progress in the field? Does the project develop or employ novel concepts, approaches, methodologies, tools, or technologies for this area? Advancing Oklahoma’s Knowledge Economy for the Next 100 Years

  36. EVALUATION CRITERIA (Compare to NIH) Investigators Are the investigators appropriately trained and well suited to carry out this work? Is the work proposed appropriate to the experience level of the principal investigator and other researchers? Does the investigative team bring complementary and integrated expertise to the project (if applicable)? Advancing Oklahoma’s Knowledge Economy for the Next 100 Years

  37. EVALUATION CRITERIA (Compare to NIH) Environment Does the scientific environment in which the work will be done contribute to the probability of success? Do the proposed studies benefit from unique features of the scientific environment, or subject populations, or employ useful collaborative arrangements? Is there evidence of institutional support? Advancing Oklahoma’s Knowledge Economy for the Next 100 Years

  38. EVALUATION CRITERIA (Compare to NIH) OVERALL EVALUATION: In one paragraph, briefly summarize the most important points of the Critique, addressing the strengths and weaknesses of the application in terms of the five review criteria. Recommend a score reflecting the overall impact of the project on the field, weighing the review criteria, as you feel appropriate for each application. An application does not need to be strong in all categories to be judged likely to have a major scientific impact and, thus, deserve a high merit rating. For example, an investigator may propose to carry out important work that by its nature is not innovative, but is essential to move a field forward. Advancing Oklahoma’s Knowledge Economy for the Next 100 Years

  39. EVALUATION CRITERIA (Compare to NIH) Modifications for New Investigators (New  newly independent, asst. prof./member) IMPLEMENTATION: When reviewing these applications, reviewers should keep in mind the experience of and the resources available to the new investigator. When considering an application from a new investigator the five new review criteria must be evaluated in a manner appropriate to the expectations for and problems likely to be faced by a new investigator. Specifically, when considering: Approach: more emphasis should be placed on demonstrating that the techniques/approaches are feasible than on preliminary results Investigator: more emphasis should be placed on their training and their research potential than on their track record and number of publications. Environment: there should be some evidence of institutional commitment in terms of space and time to perform the research. Advancing Oklahoma’s Knowledge Economy for the Next 100 Years

  40. Solicitation Forms Application & Budgets Advancing Oklahoma’s Knowledge Economy for the Next 100 Years

  41. Indirect Costs • Health Research DOES NOT allow Indirect Costs • Examples of Indirect Costs • Building & equipment depreciation, interest, operations and maintenance, overhead, administrative support, library, tuition and fees Advancing Oklahoma’s Knowledge Economy for the Next 100 Years

  42. Direct Costs • The Health Research program allows only research direct costs expenses. • Examples of allowed direct costs: • Research related: travel, supplies, equipment, patient care, alterations, rent, phone, and utilities • Examples of non-allowed direct costs: • Advertising, public relations, food, tuition and fees, housing cost, automobiles, personal computers, lobbying costs, selling and marketing costs, first class air travel, patent and licensing fees Advancing Oklahoma’s Knowledge Economy for the Next 100 Years

  43. Research Plan Maximum 15 pages! Advancing Oklahoma’s Knowledge Economy for the Next 100 Years

  44. Research Plan • Organize sections A - D of the Research Plan to answer these questions: • What do you intend to do? • Why is the work important? • What has already been done? • How are you going to do the work? • The Research Plan should be prepared in the following format: Advancing Oklahoma’s Knowledge Economy for the Next 100 Years

  45. Research Plan Specific Aims: List the broad, long-term objectives and the goal of the specific research proposed . e.g., to test a stated hypothesis, create a novel design, solve a specific problem, challenge an existing paradigm or clinical practice, address a critical barrier to progress in the field, or develop a new technology. Advancing Oklahoma’s Knowledge Economy for the Next 100 Years

  46. Research Plan B. Background and Significance: Briefly sketch the background of the proposed project, critically evaluate existing knowledge and specifically identify the gaps that the project is intended to fill. State concisely the importance of the research described in this application by relating the specific aims to longer-term objectives. If the aims of the application are achieved, state how scientific knowledge or clinical practice will be advanced. What is the innovation? Describe the effect of these studies on the concepts, methods, technologies, treatments, services or preventative interventions that drive this field. Advancing Oklahoma’s Knowledge Economy for the Next 100 Years

  47. Research Plan C. Preliminary Studies: Provide an account of the PI's progress, which led to formulating the proposed project, as well as any other information that will assist the reviewers in assessing the competence of the PI for performing the project. Advancing Oklahoma’s Knowledge Economy for the Next 100 Years

  48. Research Plan D. Research Design and Methods: Discuss in detail the research design and the clinical framework, procedures, and analyses to be used to accomplish the specific aims of the project. Describe the protocols to be used. Provide a tentative sequence or timetable for the investigation. Include the means by which the data will be analyzed and interpreted. Discuss any new methodology and its advantage over existing methodologies. Discuss the potential difficulties and limitations of the proposed procedures and the alternative approaches to achieve the aims. Point out any procedures, situations or materials that may be hazardous to personnel and the precautions that will be exercised. Advancing Oklahoma’s Knowledge Economy for the Next 100 Years