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Phylogenic subgroup of HIV-2

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Phylogenic subgroup of HIV-2 This phylogenic tree demonstrates the multiple subgroups within the HIV-2 viral family. Horizontal branch lengths represent the relative genetic distances between each group. HIV-2 predominantly comes from western Africa Within each subgroup of

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Presentation Transcript
slide1
Phylogenic subgroup

of HIV-2

This phylogenic tree demonstrates the multiple subgroups within the HIV-2 viral family.

Horizontal branch lengths represent the relative genetic distances between each group

slide2
HIV-2 predominantly

comes from western Africa

Within each subgroup of

HIV-2, there are several

countries from which

different viral strains

have originated.

There is no correlation

between the geographic

origin of an HIV-2 isolate

and its phylogenic clustering.

Geographic origins of HIV-2 strains

slide3
HIV Subtypes

Two type of HIV (genetically and

antigenically).

HIV-1 - cause of the current pandemic while

HIV-2 is found in west Africa but rarely

elasewhere.

The HIV-2 type is closely related to simian

immunodeficiency virus (SIV) found in

west Africa.

slide4
Subfamilies of retroviruses

Oncoviruses: associated with the activation of

certain cell genes leading to tumor development

Type AMouse intracisternal type A

Type B Mouse mammary tumor virus (EUR ans USA)

Type C Murine leukemia virus

Human T cell leukemia virus types I

and II, Bovine leukemia virus

Type D Mason-Pfizer virus, SAIDS virus

slide5
Virus budding forth

from the surface of

a cell. Note how the

outer mb of the virus

is composed of the

lipid bilayer mb of

the host cell studded

with integrated protein products

(envelope proteins)

of the virus.

Viral budding

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