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The companies featured in this edition are pioneers in this rapidly evolving field, pushing boundaries and unleashing the true potential of Neurotech.<br>
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March Issue 07 2023 Innovative Solutions for Chronic Pain How Neurotech Companies are Making a Difference Top 10 Emerging Neurotech Companies Changing the Future in 2023 The Future of Neuroscience Emerging Neurotech Companies Poised to Make a Big Impact Dan Schmitz CEO Petal Technology Petal
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Editor’s Note
Neurotech Innovations Rede?ning Possibilities N brain and develop transformative solutions for various neurological disorders and cognitive enhancements. The companies featured in this edition are pioneers in this rapidly evolving field, pushing boundaries and unleashing the true potential of Neurotech. eurotechnology is at the forefront of scientific and medical innovation, offering unprecedented opportunities to explore the complexities of the novel approaches to understanding and treating neurological disorders. They are paving the way for personalized medicine, where interventions can be tailored to an individual's unique brain characteristics and needs. We commend these emerging neurotech companies for their dedication to advancing our understanding of the brain and their commitment to improving the lives of individuals affected by neurological conditions. Their tireless efforts are driving the future of neurotechnology and have the potential to redefine the way we perceive and enhance our cognitive abilities. The selection process for this edition involved a meticulous evaluation of each company's technological breakthroughs, research achievements, industry reputation, and their potential to bring about significant positive changes. These emerging neurotech companies have demonstrated a deep understanding of the intricate workings of the brain and have harnessed cutting-edge technologies to develop ground-breaking solutions. We hope that this edition provides you with a glimpse into the extraordinary advancements and transformative possibilities of neurotechnology. We invite you to explore the profiles of these emerging companies and witness first- hand the profound impact they are making in shaping the future of brain research and healthcare. From brain-computer interfaces to neuroimaging tools, neurostimulation devices to neurofeedback systems, these companies are at the forefront of innovation, offering hope to millions of individuals living with neurological conditions. Their groundbreaking work spans diverse areas, including neurorehabilitation, neuroprosthetics, neurofeedback and neurodiagnostics. Thank you for joining us on this exciting journey as we celebrate the Top 10 Emerging Neurotech Companies Changing the Future in 2023 and their invaluable contributions to the field of neurotechnology. Let's dive in! By harnessing the power of artificial intelligence, machine learning and neuroplasticity, these companies are creating Soni Agarw - Saloni Agarwal
14 22 HealthTech Measure-Test-Treat for Op?mal Brain Health Ōmcare Connex Inc. Enabling One-touch Access to Healthcare and Dose-level Medica?on Adherence 32 Vibre Neurotechnologies Ctts Ctts Using Real-Time Monitoring to Reduce the Risk of Accidents in the Workplace
Cov Sty 08 Petal The Future of Telepathy is Here Technology Aicl 18 Innovative Solutions for Chronic Pain How Neurotech Companies are Making a Difference 28 The Future of Neuroscience Emerging Neurotech Companies Poised to Make a Big Impact
Editor-in-Chief Chidiebere Moses Ogbodo Managing Editor Pooja Shah Executive Editor Saloni Agarwal Visualiser David King Art & Design Head Mrunalinee Deshmukh Co-designer Paul Belin Art & Picture Editor Deepanjali Jena Business Development Manager Emily Jones Marketing Manager Bill Thompson Business Development Executives Anna Smith, Jack Miller Sales Executives Mike, Carl, John Technical Consultants David, Robert Assistant Technical Head Prashanth Hiremath Technical Head Jacob Smile Digital Marketing Manager Alina Sege Assistant Digital Marketing Manager Sagar Lahigade SME-SMO Executives Gemson Research Analyst Eric Smith Circulation Manager Tanaji Fartade sales@insightscare.com March, 2023 Contact Us: Insights Success Media and Technology Pvt. Ltd. Survey No.133/134, Brand Square, Office No. 512, Kunjir Chowk, Pimple Saudagar, Pune, Maharashtra 411027. Phone - India: 7410033802, 8956487823 Email: info@insightscare.com For Subscription: www.insightscare.com Insights Success Media Tech LLC 555 Metro Place North, Suite 100, Dublin, OH 43017, United States Phone - +1614-602-4132 Email: info@insightscare.com For Subscription: www.insightscare.com https://twitter.com/Insightscare Follow us on : www.facebook.com/InsightsCare/ We are also available on : Copyright © 2023 Insights Success Media and Technology Pvt. Ltd., All rights reserved. The content and images used in this magazine should not be reproduced or transmitted in any form or by any means, electronic, mechanical, photocopying, recording or otherwise, without prior permission from Insights success. Reprint rights remain solely with Insights Success Media and Technology Pvt. Ltd. Insights Care is powered by Insights Success Media and Technology Pvt. Ltd.
Top 10 Emerging Neurotech Companies Changing the Future in 2023 Featuring Person Company Name Description Advanced Brain Monitoring has developed and implemented mobile, user-friendly platforms for acquiring, integrating, analyzing and reporting multi-sensor data in real-world applications. Advanced Brain Monitoring, Inc advancedbrainmonitoring.com Chris Berka CEO HealthTech Connex Inc. focuses on technology-based innovations for rapid impact in health improvements and outcomes. Dr. Ryan C. N. D’Arcy President & Chief Scientific Officer Healthtech Connex healthtechconnex.com Neeuro Pte Ltd is empowering minds to overcome brain health challenges through artificial intelligence and digital therapeutics. Dr. Alvin Chan CEO NEEURO PTE LTD neeuro.com NeuroPro leverages latest advances in computer science and digital technology to create new and improved tools that support researchers, clinicians and innovators in pushing the boundaries of brain science and its applications. Dr. Jamil El-Imad Chief Scientific Officer NeuroPro neuropro.ch Nia Therapeutics is developing first-in-class therapeutic devices to restore memory after brain injury and degenerative disease. Nia Therapeutics niatherapeutics.com Dan Rizzuto CEO Ōmcare is a digital health company that aims to change the way the world cares by extending the reach of caregivers, increasing medication adherence and improving treatment outcomes through the power of remote care and two-way video technology. Omcare Inc omcare.com Lisa Lavin Founder & CEO PainQX painqx.com PainQx is a Philadelphia based startup that has developed a way of objectively measuring pain in humans. Frank Minella CEO Petal Technology petal.tech Dan Schmitz CEO Petal Technology is a neurotech startup helping developers make brain-computer interface apps. Sense Neuro is developing non-invasive technology to rapidly detect stroke (by subtype) and TBI, and continuously monitor brain injury. Sense Neuro senseneuro.com Geoff Klass CEO Vibre is a company that develops Brain-Computer Interfaces (BCIs), systems that create a direct connection between the mind of the user, and any technology. Raffaele Salvemini CEO & Founder VIBRE vibre.io
Cover StoryPetal Cover Story Technology
Cover Story Dan Schmitz CEO Petal Technology
Top 10 Emerging Neurotech Companies Changing the Future in 2023 T T Scientists have come up with an advanced technology using artificial intelligence that can figure out what people are looking for, simply by monitoring brain activity. This involves AI that interacts with an algorithm to analyze brain scans and determine the user’s needs, which has led to a direct connection between computers and the brain. elepathy – the ability to read each other’s thoughts without the use of speech has been a staple of science fiction for decades. However, today we have come closer to it in the real world. With the above understanding, researchers point out that not only thoughts but also sensory experiences can be communicated from one brain to another. Petal Technology, a growth-heading healthcare disruptor, and leading business have allowed people to interact with their surroundings through their software, further responding to brainwave activity. The company, through its R&D processes, offers a software library of metrics. Several artists, engineers, and academics have used Petal to enable their own experiences of using brain-computer interfaces. For instance, a software engineer uses Petal Metrics to stream data from multiple Muse headsets. Or, Petal Metrics API has been used to turn on a lamp through the use of a human mind. possible. We have had a great 2022 and look forward to helping more customers to realize the untapped potential of the human brain.” The Journey So Far With curiosity over the technological marvels of Petal Technology, we at Insights Care reached out to Dan Schmitz, the CEO of the company, who shares his vision of the future and offers people with augmented superpowers. Dan reflects on his journey to becoming the CEO of Petal Technology, where he begins by stating, “Years ago, I realized my thirst for discovery on a dinosaur bone and fossil expedition and understand vividly the thrill of searching for scientific truths. This passion is the foundation for my work in developing cutting-edge products for people in need.” Integrating R&D Effort Petal is a neurotechnology company that makes software to measure biometric data. Dan and his team formed the company as a means to commercialize the technology that they had been researching and developing themselves. Dan was formally educated in converting research and development breakthroughs to wealth, earning valedictorian status upon completing his Master of Science in Technology Commercialization degree from the Red McCombs Business School at the University of Texas. “There is a pioneering spirit within the R&D communities that conveys optimism, curiosity, and high probabilities of discovery,” states Dan. These pillars gave him the confidence to lead his team in pursuing ways to provide clever solutions to big problems. “It’s my team, my clients, and interactions with end users, though, that have taught me the most about leading an organization toward a better future,” comments Dan. Appreciating the team, Dan comments, “These are the teams we have been engaged with since the beginning and who continue to inspire us to push the boundaries of what’s
T However, he admits that along the journey, one is always entitled to make mistakes. He states, “There have been costly mistakes and lessons that I've learned along the way - time that was spent that can't be recovered.” He explains, “One’s immediate environment and context have the potential to significantly influence their state of mind.” “For instance, consider how a person might feel more anxious in a crowded train station than in solitude. Simply being in a public setting vs. a private environment may influence one's level of awareness, fear, stress, or other detectable states,” elaborates Dan. From these experiences, though, Dan and his team have grown wiser as a unit and can better manage their way through the foggy unknown ahead. He adds, “We are at an exciting point in our company’s growth, with strong momentum heading into the rest of the year, and I can’t wait to reveal what lies ready to emerge from beneath the dust.” Additionally, having the ability to measure brains in the field as opposed to special labs or offices can provide information that was not previously possible. However, as portable biometrics becomes increasingly pervasive, Petal expects transformative improvements in access to healthcare services and products by way of telehealth, teletherapy, or just telecare in general. Use of Brainwave Data En-cashing Commercial Segment Petal has found success in its first commercially-available software product, Petal Metrics, by enabling brainwave data to be remotely collected, analyzed and delivered in real-time. The software product can be used as a standalone application or integrated into existing software using PETAL’s APIs. Simply put, it is an intermediary between human brains and software systems. Customers’ Expectations is Where to Head The healthcare providers that survive the decade will be the ones who look to the developments of such a macroenvironment, outside of the healthcare industry. Petal Metrics supports a growing number of input sensors and wearable devices that can then communicate with a limitless number of software applications and Internet-connected products. While neurotechnology combines several sciences into a complex, complicated system of jargon, formulas, procedures, and methods that comes with steep learning curves, Petal acts as a solution and simplifies the entire process to the point where users can see their mental states with one command or the push of a button. ’ “We are making it as easy-as-possible to unlock the full potential of remote biometrics,” suggests Dan To Comprehend the Brain in a Better Way Dan and his team aim to better understand the brain so that they can augment human abilities as a species. It could mean - creating systems and methods to read signals that may indicate mental states. Dan believes that this is important in many fields but has profound potential in healthcare.
However, the providers who fail to even consider telecare as an option will do so at their own peril. Ideas are of Great Value To the budding entrepreneurs who desire to venture within the software development industry, Dan advises, “You can dream and speculate and obsess over an idea until the end of time. Ideas are useless until they are put into action. Share them, do them, be open to their evolution. An idea is always perfect until it needs to actually be animated. Bring it to life to bring actual change.” Furthering Neurotechnology From the beginning, Petal has strived to facilitate the use of neurotechnology in products and services, being sensitized to its customers’ experience with knowledge of the underlying science and technology. The company has already simplified the process of making brainwave data accessible and usable and will continue to provide easy-to-use products and excellent customer support. “Looking forward, we expect to integrate Petal into more software systems and organizations so they can realize the tremendous value that comes with real-time biometric analysis software. Our teams will scale up, more detections will become available, and we will continue to build new relationships on our path toward understanding and unlocking the potential of the human brain,” concludes Dan. According to Dan, “Customers are becoming summoners and learning to expect to get what they need, where and when they need it. Care is no exception.” Advances in technology have made it easier than ever to securely gather, analyze and deliver biometric data from anywhere. “With customers expecting care where and when they need it, the organizations that will find success are those who modernize and grow the capability to interact with their patients and customers remotely,” believes Dan.This decision to embrace newer technologies is not trivial, especially given the high stakes in this industry.
HealthTech Top 10 Emerging Neurotech Companies Changing the Future in 2023 Connex Inc. W technology company has made it possible through its industry-leading medical device, the NeuroCatch® Platform, that could record your brain's objective, and physiological responses quickly across various brain conditions, including brain injuries, neurological diseases, mental health and brain optimization. Measure-Test-Treat for Op?mal Brain Health hat if just like blood pressure, we could measure the complexity of the brain? HealthTech Connex, a neuro-health embedded brain imaging labs in the world. The foundational problem was that – as powerful as these amazing labs are – they continue to be completely inaccessible to the frontline points of care. The NeuroCatch® Platform was developed as the solution to this major barrier in state-of-the-art brain health: to bring the most sensitive and objective evaluation to all points needed on this planet and beyond. Brief us about yourself and shed some light on your role and responsibility at the company. The company runs on the following business model to make optimal brain health possible: I'm a Canadian neuroscientist, researcher, innovator and entrepreneur. Being an endowed university professor, I'm a world-renowned expert in neurotechnology. I've co-founded HealthTech Connex Inc. (HTC) and serve as President and Measure: Offering an objective evaluation of cognitive functions, which is delivered in minutes at the point of care. Test: Administering high-quality research services to advance healthcare innovations for a positive impact on brain health. Treat: Focusing on comprehensive therapies using advanced, non-invasive brain technologies to help treat people with neurological conditions. Ÿ Ÿ Ÿ The mission of HealthTech Connex (HTC) is to posi?vely impact a billion brains. In medicine, you can't treat what you can't measure. Accordingly, our vision is to launch the NeuroCatch® Pla?orm globally as the most accessible, sensi?ve, and highest-quality evalua?on of cogni?ve brain health and performance. In an interview with Insights Care, Ryan C. N. D'Arcy, the President and Chief Scientific Officer, talks about the company's contribution to enabling care for neurological conditions like concussion and brain injury, dementia, PTSD, mental health, and more, Following are the excerpts from the interview. Kindly tell us the source of inspiration. What led you to venture into the Neurotech industry? We are neuroscience and neuroimaging experts who develop and run some of the most advanced hospital- 14 www.insightscare.com March 2023
Dr. Ryan C. N. D'Arcy President & Chief Scien?fic Officer HealthTech Connex Inc. 15 www.insightscare.com March 2023
Chief Scientific Officer. HealthTech Connex translates neuroscience advances into health technology breakthroughs. What are the mission, vision and values shared by the company? The mission of HealthTech Connex (HTC) is to positively impact a billion brains. In medicine, you can't treat what you can't measure. Accordingly, our vision is to launch the NeuroCatch® Platform globally as the most accessible, sensitive, and highest-quality evaluation of cognitive brain health and performance. NeuroCatch® technology is deployed in clinical trials and identifying novel, effective treatment interventions. These evidence-based innovative treatments are scaling up to positively impact people through our clinic and network of clinics. 16 www.insightscare.com March 2023
Tell us about the core products and services that the company offers to support the needs of the clients/patients. How are these different from other companies in the market? company, we have developed NeuroCatch® as a solution to this problem. What specific R&D operations is your company leading at present? Why do you find them essential in developing or improving neurotech solutions? HTC's family of businesses works together to attract the latest and greatest healthcare innovations for brain and mental health. With clinical neuroscience and brain vitality as a premier focus, we connect science and R&D to product breakthroughs–providing translational neuroscience innovations to care sectors and communities worldwide. HealthTech Connex exists as the parent company for 3 entities, driving an HTC flywheel model: NeuroCatch Inc. - The NeuroCatch® Platform (NCP) The NeuroCatch® Platform (NCP) is an industry-leading medical device that offers an objective evaluation of cognitive function, which is delivered in minutes at the point of care. NeuroCatch® is deployed in hospitals, clinics, sports venues, care homes, high schools, and space missions. Centre for Neurology Studies (CNS) The Centre for Neurology Studies (CNS) runs clinical trials in the field of neuroscience and brain health, the core focus revolving around medical devices and pharma in neurological populations. The CNS team works with global partners to build evidence-based treatments from start-up studies to international, multi-site clinical trials. Surrey Neuroplasticity Clinic (SNPC) The Surrey Neuroplasticity Clinic (SNPC) deploys all emerging innovations identified by NeuroCatch® and validated by CNS clinical trials through our clinic and growing network of clinics in North America. Brief us about the rising need for neurotechnology in the healthcare sector. How will it impact the way patients receive treatment and the clinical decisions taken by care providers? HTC is a science-based company, with established leadership and breakthrough technology. Specific R&D focus continues to make NeuroCatch® even more accessible and powerful through software and hardware advances to empower clinical-grade treatments and unleash optimized brain performance. What advice would you like to give to budding entrepreneurs and enthusiasts who desire to venture into the neurotech Industry? Now is the time. Neurotech is one of the most exciting emerging industries, with unimaginable potential to address the wickedest problems humanity faces. How do you envision scaling the company's services and operations in 2023 and beyond? The current generation of NeuroCatch® is scaling in North America and preparing for global expansion. In parallel, the next generation of NeuroCatch® is beginning development to be faster, easier, and more accessible with expanded brain health evaluation capabilities. Design-inspired by ubiquitous vital signs, soon NeuroCatch® will be as accessible as blood pressure to enable regular brain health management and optimization. The technology will scale further to find innovative treatments that challenge our most devastating brain injuries and diseases. We anticipate the emergence of this scaling within 5 years. The critical need for an accessible and objective measure of brain health is essential for managing and preventing tragic brain health injuries and diseases. As a leading R&D 17 www.insightscare.com March 2023
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Innovative Solutions for Chronic Pain How Neurotech Companies are Making a Difference C hronic pain is a pervasive and debilitating condition that affects millions of people worldwide. Traditionally, managing chronic pain has been a complex and challenging task, often relying on medication and invasive procedures. However, with the advent of neurotechnology, there is renewed hope for more effective and personalized approaches to pain management. of life. It can result from various conditions such as arthritis, fibromyalgia, neuropathy, or injuries. Beyond the physical discomfort, chronic pain can also lead to emotional distress, sleep disturbances and social isolation. Traditional treatments often focus on symptom relief without addressing the underlying causes, making effective pain management a crucial yet elusive goal. In this article, we will explore the innovative solutions offered by neurotech companies and how they are revolutionizing the field of chronic pain management. The Rise of Neurotech in Pain Management Neurotechnology involves the application of technology and neuroscience principles to understand and modulate the nervous system. By directly targeting the brain, spinal cord, or peripheral nerves, neurotech offers innovative approaches to pain management that go beyond conventional methods. These advancements hold the potential to provide relief for individuals suffering from chronic pain, transforming their lives and improving overall well-being. The Scope of Chronic Pain Chronic pain is a long-lasting pain that persists beyond the usual recovery period or occurs along with a chronic health condition, such as arthritis. It is a significant health problem that affects millions of people worldwide and has significant economic consequences. Traditional pain management methods such as opioids have been associated with negative side effects and addiction. Therefore, there is a need for innovative solutions for chronic pain management. Neurotech Companies Making a Difference Medtronic: Ÿ Understanding Chronic Pain and Its Impact Medtronic is a leading neurotech company that has pioneered advancements in the field of chronic pain management. Their innovative technologies include Chronic pain refers to persistent pain that lasts for months or even years, significantly impacting an individual's quality 19 www.insightscare.com March 2023
Deep Brain Stimulation (DBS) implantable devices such as spinal cord stimulators and peripheral nerve stimulators. These devices deliver electrical impulses to the nerves, interrupting pain signals and providing relief. With customizable programming options and improved battery life, Medtronic's neurostimulation systems offer personalized pain management solutions. Ÿ Deep Brain Stimulation (DBS) involves implanting electrodes in specific areas of the brain and delivering electrical impulses to modulate neural activity. While primarily used for movement disorders such as Parkinson's disease, DBS is being explored as a potential treatment for chronic pain. Companies like Boston Scientific and St. Jude Medical (Abbott) are actively developing advanced DBS systems that target pain-related brain regions, offering hope for individuals who have not found relief through other interventions. Ÿ Nevro: Nevro is revolutionizing chronic pain management with its proprietary technology called High-Frequency Spinal Cord Stimulation (HF10 Therapy). This breakthrough therapy delivers electrical pulses to the spinal cord at a higher frequency, resulting in pain relief without the tingling sensations commonly associated with traditional spinal cord stimulators. Nevro's HF10 Therapy has demonstrated superior efficacy in clinical trials and offers a novel approach to managing chronic pain with improved patient satisfaction. The Future of Neurotech in Pain Management The innovative solutions offered by neurotech companies are just the beginning of a revolution in chronic pain management. As our understanding of the nervous system deepens and technology continues to advance, we can expect more precise and targeted therapies for pain relief. Emerging technologies such as optogenetics and neuromodulation techniques hold tremendous potential for unlocking new approaches to pain management. Quell: Ÿ Quell is a neurotech company that focuses on non- invasive solutions for chronic pain management. Their wearable device uses transcutaneous electrical nerve stimulation (TENS) technology to stimulate sensory nerves, triggering the body's natural pain relief mechanisms. Quell's innovative approach provides on- demand pain relief without the need for medications or invasive procedures. The device is user-friendly and can be easily integrated into daily activities, empowering individuals to take control of their pain management. Ethical Considerations and Challenges While neurotech offers promising solutions for chronic pain, ethical considerations and challenges must be addressed. Access to these advanced treatments, cost considerations and long-term safety and efficacy studies are crucial factors that need careful attention. Moreover, the integration of neurotech solutions should prioritize a multidisciplinary approach, involving healthcare professionals, researchers and patients to ensure the best possible outcomes. Advancements in Brain Stimulation Transcranial Magnetic Stimulation (TMS) The landscape of chronic pain management is being reshaped by neurotech companies, bringing renewed hope and relief to individuals living with persistent pain. By leveraging cutting-edge technologies and innovative approaches, these companies are revolutionizing pain management beyond traditional methods. As research and development continue to push the boundaries of neurotechnology, we can envision a future where chronic pain becomes more manageable, allowing individuals to regain control of their lives and experience improved well- being. Ÿ Transcranial Magnetic Stimulation (TMS) is a non- invasive brain stimulation technique that uses magnetic fields to modulate neural activity in specific regions of the brain. While initially developed for treating psychiatric disorders, TMS has shown promise in managing chronic pain as well. Neurotech companies like Magstim and BrainsWay are at the forefront of developing TMS technologies that target pain-related brain circuits, providing a novel and non- pharmacological approach to pain management. - Saloni Agarwal 20 www.insightscare.com March 2023
Top 10 Emerging Neurotech Companies Changing the Future in 2023 Ōmcare W The only correct answer is CARE! People are most comfortable when they are in their own place of comfort. When illness occurs, individuals' first instinct is to instantly check it with healthcare professionals for proper diagnosis and medical assistance. hat is the best thing to do for yourself or your loved ones when going through illness? Let's dive into the story of Ōmcare in its ambitious journey to become an efficient remote care solution. Promoting Independence and Dignity for Aging Adults Ōmcare is a digital health company that has pioneered a customizable home health platform that enables one-touch access to telehealth services, aggregated RPM, and medication dispensing with visual confirmation of medication adherence. For various reasons, going to healthcare or medical care centre is not always a viable option. In such a situation, a digital healthcare solution can prove to be a great sigh of relief. We all have those extra special people that impact us deeply at some point in our life. For founder Lisa Lavin, this special person was her grandmother, Mildred. Mildred was Lisa's primary caregiver during a difficult period in her childhood. A remote digital care solution provider company, Ōmcare, came into existence to provide effective healthcare services for you and your loved ones from the comfort of your home. Based in Minneapolis, Ōmcare is a digital health company that aims to change the way the world cares by extending the reach of caregivers, increasing medication adherence, and improving treatment outcomes through the power of remote care and two-way video technology. By partnering with pharmacies, payers, providers, and family caregivers, Ōmcare strives to help people live healthier, more vibrant, independent lives and reduce healthcare costs. Ōmcareallows people to age in place, bringing humanity and liberation to the aging process. It also provides greater access to care to more people since it's less expensive and can reach rural areas. Dedicated to providing one-touch access to various healthcare needs of the people is Ōmcare's Founder and CEO,Lisa Lavin. 22 www.insightscare.com March 2023
The Visionary Founder Lisa Lavin is a serial entrepreneur with over 25 years of experience building new businesses from the ground up within the healthcare and high-tech sectors. Lisa is active in local and national organizations that support entrepreneurialism and women in business. Moreover, Lisa is a Minnesota Cup Division winner and Eureka Award winner for Innovation. She was recognized by Minneapolis / St. Paul Business Journal as one of 25 Women to Watch, Minnesota Business' Real Power 50, and The New York Observer's 2020 List of the Hottest "Flyover Tech" Companies in Digital Health. Lisa Lavin, Founder & CEO Ōmcare 23 www.insightscare.com March 2023
Lisa and her grandmother were very close. As Mildred aged, she developed dementia and was eventually placed in a nursing home because there was no other way to help her maintain her independence. Awards and Recognition Ÿ 2020: New York Observer's Hottest Tech List (JP Morgan Conference) Through this experience, Lisa became impassioned not only for her grandmother but for all aging adults. Lisa vowed that she would do everything she could to promote independence and dignity for older adults. "This generation deserves much more than a nursing home," says Lisa. "They deserve connectedness, love, and a full, healthy, liberated life.” Ÿ 2020: Named AARP Portfolio Company Ÿ 2021: Named a finalist in the Accenture HealthTech Innovation Challenge All-in-one Healthcare Solution consumer expectations while ensuring the comprehensive suite of capabilities required for the home is together in an easy-to-use, one-touch interface. It brings everything together—down to the data. Home is the new site of care, but it is messy and requires many solutions pieced together today to work. And the patient is always in charge of piecing them together by themselves. Greater Reach and Lower Cost For example, if your mom has a telehealth appointment. Hopefully, she has a tablet, and if she does, she knows where it is, and it's charged. Then if she needs to take her blood pressure or give the doctor any other vitals, she needs to track down those devices too. It simply doesn't work. The world's healthcare needs are on a constant rise. Getting customized medical attention from time to time requires people to keep visiting healthcare centers from time to time and also pay high amounts for simple consultations. It is difficult for older adults to visit doctors regularly. The chances of worsening their health cannot be neglected if they have to go to hospitals on a regular basis. Ōmcare Ōmcare opens up the home as a legitimate site of care by creating a single, all-in-one solution that addresses 24 www.insightscare.com March 2023
more about the challenges to be expected and the possible solutions, words of advice from experienced entrepreneurs, such as Lisa, can prove to be an important piece of counsel. Exhibiting Excellence "Because my medications are packaged and I am on a schedule to have them dispensed, I don't have to think about them and remember to take them. " –Pilot participant Offering her years of entrepreneurial wisdom to the individuals who wish to come up with their own technological venture, Lisa tells them to "Design something you know will help so many people and get a good team around you. Both of those will make the bright days seem brighter and the hard days not as bad." "It's the first of its kind. It's really innovative," - Brett Anderson, Ecumen Senior Care COO (pilot partner). Envisioning Future With the help of technology and advanced hardware, the world is going digital. The path ahead for Ōmcare is filled with great possibilities. The company plans to keep on improving its existing solutions and bring out more technology products to best assist the needs of patients remotely. Speaking about plans for the company in the near future, Lisa says, "In the near future, we will be fully commercialized by rolling out the Ōmcare Home Health Hub® with senior care providers, pharmacy partners, and Medicare Advantage providers." provides such people with the go-to option for getting one- stop assistance for their healthcare needs. "Ōmcare allows people to age in place, bringing humanity and liberation to the aging process. It also provides greater access to care to more people since it's less expensive and can reach rural areas," says Lisa. Reducing the Load on Healthcare Systems with Technology Imagining any industry without a technology solution is nearly impossible in current times. Every industry has been quickly adopting technology solutions. However, it is important to ensure that with technology additions, the processes are getting streamlined and not complicated. For technology to be beneficial, it has to work for both sides of the equation—the healthcare providers and the patients. When she discusses adding technology solutions to the healthcare sector and providers, Lisa says, "For technology to be beneficial, it has to work for both sides of the equation—the healthcare providers and the patients." Furthermore, she says, "With this in mind, we've done rounds of the voice of consumer feedback, user testing, and, most importantly, made sure that non-clinical team members can handle our product." "That way, we use technology to lessen the burden on the healthcare system and providers, not add to it," she added. Showing the Path to Entrepreneurs An entrepreneurial path requires one to constantly assess the challenges that could come in their way. For knowing 25 www.insightscare.com March 2023
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N euroscience is the study of the nervous system, including the brain, spinal cord and peripheral nerves. It is a rapidly evolving field that has the potential to revolutionize our understanding of the brain and how it works. As we learn more about the brain, we can use this knowledge to develop new treatments for neurological and psychiatric disorders, improve education and enhance human performance. In this article, we will explore the future of neuroscience and how emerging neurotech companies are poised to make a big impact. Understanding the Future of Neuroscience Neuroscience is a multidisciplinary field that encompasses the study of the nervous system, including the brain, spinal cord and peripheral nerves. Its ultimate goal is to comprehend the intricate workings of the brain and how it gives rise to our thoughts, emotions and behaviors. By gaining deeper insights into the inner workings of the brain, researchers aim to develop treatments for neurological disorders, enhance cognitive abilities and unravel the complexities of consciousness itself. Neuroscience and Education Neuroscience has the potential to transform education by providing insights into how the brain learns and processes 29 www.insightscare.com March 2023
information. Research has shown that teachers who have a better understanding of neuroscience concepts are better equipped to develop effective teaching strategies. By incorporating neuroscience into education, we can improve student learning outcomes and help students reach their full potential. Kernel's technology has the potential to make brain- machine interfaces more accessible and affordable. Openwater: Ÿ Openwater is another neurotech company that aims to revolutionize neuroscience through technological advancements. Led by Mary Lou Jepsen, Openwater is developing wearable devices that utilize infrared light to create high-resolution images of the brain and body. This non-invasive imaging technology has the potential to transform diagnostics, enabling early detection of neurological disorders and offering personalized treatments. The Convergence of Technology and Neuroscience Technological advancements are playing a crucial role in propelling neuroscience into the future. As our understanding of the brain increases, so does our ability to develop cutting-edge tools and techniques for studying it. Neuroimaging techniques such as functional magnetic resonance imaging (fMRI) and electroencephalography (EEG) have revolutionized our ability to visualize brain activity. Additionally, the advent of artificial intelligence (AI) and machine learning has enabled the analysis of vast amounts of brain data, leading to novel insights and discoveries. Implications for Healthcare and Beyond The impact of these emerging neurotech companies extends far beyond the realm of neuroscience research. Their advancements hold the potential to reshape healthcare as we know it. By providing new tools for understanding the brain, these companies can accelerate the development of treatments for conditions such as Alzheimer's disease, Parkinson's disease and mental health disorders. Additionally, the integration of brain-machine interfaces into everyday life could lead to breakthroughs in fields such as prosthetics, virtual reality and human-computer interaction. Emerging Neurotech Companies While major institutions and universities have traditionally dominated neuroscience research, a new wave of neurotech companies is emerging, poised to make a big impact in the field. These companies combine scientific expertise with technological innovation to develop groundbreaking solutions for understanding and harnessing the power of the human brain. Ethical Considerations and Challenges As with any technological advancement, the emergence of neurotech companies also raises ethical considerations and challenges. Issues surrounding privacy, data security and informed consent must be carefully addressed to ensure the responsible and ethical use of these technologies. Additionally, equitable access to neurotechnologies must be prioritized to prevent further disparities in healthcare and cognitive enhancement opportunities. Neuralink: Ÿ One prominent neurotech company making headlines is Neuralink, co-founded by entrepreneur Elon Musk. Neuralink aims to develop high-bandwidth brain-machine interfaces (BMIs) to enable seamless communication between the human brain and external devices. With the potential to revolutionize healthcare, Neuralink's technology holds promise for restoring lost sensory functions and treating neurological disorders. It also has the potential to revolutionize the field of neuroscience and change the way we interact with technology. The future of neuroscience is an exciting frontier that promises to unlock the mysteries of the human brain and transform the way we understand ourselves. With the convergence of technology and neuroscience, emerging neurotech companies are poised to make a significant impact. From brain-machine interfaces to advanced imaging technologies, these companies are driving innovation and pushing the boundaries of what is possible. As we navigate this new era, it is essential to embrace the potential of these advancements while remaining mindful of the ethical considerations that come with them. By harnessing the power of neuroscience and technology hand- in-hand, we can pave the way for a brighter future where the full potential of the human brain is realized. Kernel: Ÿ Kernel, founded by entrepreneur and neuroscientist Bryan Johnson, focuses on the development of advanced neural interfaces. The company aims to create non-invasive devices that can read and write neural code, unlocking new possibilities for understanding and augmenting brain function. Kernel's innovations have the potential to enhance memory, cognition and even expand human capabilities. - Saloni Agarwal 30 www.insightscare.com March 2023
Top 10 Emerging Neurotech Companies Changing the Future in 2023 Vibre Neurotechnologies Using Real-Time Monitoring to Reduce the Risk of Accidents in the Workplace W abides by this philosophy by evaluating the mental fatigue of personnel involved in high-risk or high mental load jobs, such as—the energy sector, oil and gas, aviation, aerospace, surgery, and others related—as accidents in these workplaces are more likely to occur to precisely due to the accumulation of mental fatigue and the onset of micro sleep during work activities. hen no tools are capable of solving a given problem, a man must be able to resort to neurotechnologies. Vibre Neurotechnologies neurotechnologies, identifying a boundless potential in this field in future years. We have always been fascinated by the "decoding" of the human brain: a mysterious and fascinating machine. The dream was (and is) to bring this technology into everyday life, combining ever-smaller devices and real, practical needs. Starting in 2017, we began researching and developing solutions in various fields, trying to continuously test what the market was asking for. Brief us about yourself and shed some light on your role and responsibility at the company. Through Neuroframe, an innovative software and a wearable device worn over like a headband—one can measure attention, mental fatigue, and sleepiness during jobs that require high levels of concentration, thus helping you to prevent errors due to fatigue. The device captures brain data to provide real-time assessments that contain information on the worker's mental state during the sequence of jobs performed. I have a degree in Biomedical Engineering, 32 years old, I have been building companies since the age of 20. Inserted in 2020 in the Forbes Italia under 30 list. Today I hold the role of CEO at Vibre. What are the mission, vision and values shared by the company? In an interview with Insights Care, Raffaelle Salvemini, the CEO and Founder share Vibre's journey to bringing this technology into enabling safer human interaction at high- risk workplaces. We have always believed that neural interfaces could make a real contribution to the world. A technological revolution without comparison. Putting the human brain and mind at the center of everything. Usually, we tend to think of neurotechnologies as technology capable of "commanding" objects from a distance. We have always avoided this association, trying to carry on our philosophy: neurotechnologies must help man in activities in which there are no tools capable of solving a given problem. Following are the excerpts from the interview: Kindly tell us the source of inspiration. What led you to venture into the Neurotech industry? Almost all the founders of Vibre Neurotechnologies have the same academic background: university studies in biomedical engineering. Through a series of coincidences, we met each other and identified a common interest in Today our focus is on mental fatigue and drowsiness by monitoring personnel involved in high-risk jobs in energy, oil and gas companies. In the long term, we will introduce 32 www.insightscare.com March 2023
Raffaele Salvemini CEO & Founder Vibre Neurotechnologies One of the main causes of errors or accidents at high-risk workplaces is precisely the accumula?on of mental fa?gue and the onset of micro sleep during work ac?vi?es. To date, there are no systems capable of measuring these values, except by exploi?ng neural interfaces. But we have managed to bring to the market a concrete solu?on that meets the needs of companies, by delivering our tools and data devices that improve workers' safety. neurotechnologies in different application sectors, thanks to the possibility of miniaturizing the devices. In the coming years, devices designed by us over the last few years will be produced. Today we are at the first step of our plan. The goal is to land in different sectors. One of our solutions in the pipeline is the use of mental fingerprints as an authentication system. sector, oil and gas, aviation, aerospace, surgery, Formula 1, etc. See, for example, the Windy Minds project conducted with Edison Spa or the publications made with hospitals in Italy. One of the main causes of errors or accidents is precisely the accumulation of mental fatigue and the onset of micro sleep during work activities. To date, there are no systems capable of measuring these values, except by exploiting neural interfaces. We work on two different levels: analysis of entire company processes to identify critical points, correlating them with time slots, temperatures and any other parameters; real-time analysis by sending alerts. Tell us about the core products and services that the company offers to support the needs of the clients/patients. How are these different from other companies in the market? Using the most comfortable devices available on the market today, we evaluate the mental fatigue of personnel involved in high-risk or high mental load jobs, such as the energy One of the main differences is the autonomy of action: companies use our tools and the data devices supplied with 33 www.insightscare.com March 2023
complete autonomy, without our intervention. Secondly, we have managed to bring to the market a concrete solution that meets the needs of companies, so it is a B2B segment. Furthermore, we do not operate in the health sector, except by intervening with the health workers themselves. So we decided to verticalize companies from completely different sectors. Brief us about the rising need for neurotechnology in the healthcare sector. How will it impact the way patients receive treatment and the clinical decisions taken by care providers? With Vibre Neurotechnologies we work to identify critical issues in surgeons. About 70%-80% of errors that occur during surgical operations are caused by mental fatigue. Mental fatigue is a growing problem in every activity, from study to work and is likely to gradually lead to burnout problems. Neurotechnologies are today the only truly objective and valid tool to be able to prevent problems related to mental stress. solutions to be placed on the market. Internally, we are constantly developing new algorithms that allow us to refine our metrics and, consequently, our evaluations. One of the aspects that we pay the most attention to in our internal research is the identification of increasingly localized areas of the brain involved to produce micro devices, invisible and without any encumbrance. We believe that neurotechnologies will only be able to play a role in daily life when they become almost invisible. What specific R&D operations is your company leading at present? Why do you find them essential in developing or improving neurotech solutions? Vibre Neurotechnologies follows the latest neuroscientific research in the world, translating them into practical 34 www.insightscare.com March 2023
met. In fact, the care we have towards our customers is precisely on the definition of simple use protocols suitable for their purposes. What advice would you like to give to budding entrepreneurs and enthusiasts who desire to venture into the neurotech Industry? I always give very precise advice: avoid being fascinated by superhero applications. In our journey, but without going too far in time even a few days ago, we met people who were more fascinated by what one might see in a science fiction film set in the year 3000. We need to focus on concrete solutions that can help companies and people, with something that until now could not be done. To give an example: controlling an industrial machine with remote thinking doesn't make much sense. Yes, it's fascinating. But the accuracy will never be as good as a classic controller. And the risk of error would be too high. And above all, why not control it with remote control and with your own hands. How do you envision scaling the company's services and operations in 2023 and beyond? In what way do you consider technological advances to be a pathway in conducting your company's operations? We have validated our monitoring solution (Neuroframe) in the last two years (from Covid onwards). Today we intend to scale up to medium and large companies, beyond the Italian borders. At Vibre we believe that the technological aspects to be evaluated in our processes are essential: Tell us about your service 'BrainArt.' How is it helping the audience to learn about Vibre? Increasingly accurate and increasingly automated information Complete autonomy of the clients in the use of neurotechnologies (without being experts in neuroscience) Extreme miniaturization of the devices to have a convenience never seen before. Ÿ Ÿ BrainArt is a service that we launched in 2018 and is still very popular today among individuals and companies. It is a system capable of transforming "emotions" into abstract paintings. It was a project that we launched to get as much data as possible at the beginning and to viralize neurotechnologies in Italy. To date, tens of thousands of BrainArts have been collected and, consequently, the people who have touched this technology first-hand. Companies use BrainArt in their events to get a bigger audience and acquire more contacts. BrainArt uses listening to a piece of music as input and, after listening, a picture is produced (then printed on canvas when requested and associated with a scientific brochure that analyzes the experience). I think it's noteworthy because it was an idea that allowed us to make ourselves known and make known, in a light way, a technology that is still little known. Ÿ We are extremely focused on these three values, regardless of the sector in which we apply our solutions. What endeavors is the company currently pursuing to improve its service measures for the clients/patients? We collect feedback from the relevant departments of our client companies on a daily basis. It is important that the use of our devices and our software is easy and without any obstacles. These technologies are still being improved (even if they have been developing for more than sixty years) and therefore, depending on the customer, there may need to be 35 www.insightscare.com March 2023
