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Learn about how skin color is determined by melanocytes, the effects of melanin production, and the functions of skin appendages such as sweat glands, hair, and nails. Explore common skin disorders, burns, and aging aspects.
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Skin color • All humans have roughly the same number of melanocytes. Color is based on the activity, not the number. • Increase in Melanin production in those exposed to more UV radiation, decreased Melanin production in those exposed to less UV radiation • Melanin is a “natural suncreen”. Dark skinned people seldom have skin cancer due to its effectiveness, however when they get it, it is more deadly.
Skin color • Tanning is the body’s built in protective mechanism, it leads to increased melanin production and protection from UV radiation. • Albinos genetically can’t produce melanin and have to be extremely cautious about exposure to the sun. • Skin color is controlled by many factors: • Amounts and kind of pigment present • Amount of carotene present • Amount of oxygen bound to hemoglobin • Emotional stimuli
Skin Color • Cyanosis- when blood is poorly oxygenated and skin appears blue • Redness- can indicate embarrassment, fever, hypertension, inflammation or allergy • Pallor (paleness)-emotional stress(fear, anger), anemia, low blood pressure, impaired blood flow into the area • Jaundice (yellow)-liver disorder • Bruises (black and blue)-blood escapes circulatory system and clots in tissue spaces. • Hematomas-unusual bruising-VitaminC deficiency or hemophilia are common causes
Skin Appendages • Sebaceous Glands-oil glands, found everywhere but palms of hands and soles of feet • Sebum-mixture of oily substances and fragmented cells, keeps skin soft, prevents brittle hair, kills bacteria. • During adolescence hormones increase amount of oil produces and skin is oilier at that time in life. • Acne is infection of the sebaceous glands • “Cradle cap” is due to overactive sebaceous glands in infants. Yellow brown crust, comes off as dandruff.
Sweat Glands • 2 kinds of sweat glands (Sudoriferous glands) • Eccrine- produces primarily water, it is odorless and actually inhibits bacterial growth. Helps body regulate temperature. You can lose 7L of water on a hot day • Apocrine-produces fatty acids and proteins which provides a food source for bacteria on skin. The by-product of those bacteria is body odor. • Sweat reaches the skin by a duct that opens as a pore.
Hair • Functions: • Guards head against bumps • Eyelashes protect the eyes • Keeps foreign particles out of respiratory tract • In the past helped with keeping the body warm.
hair • It is produced by a hair follicle. Root is enclosed in follicle, the shaft is the part projecting from the surface. • Hair is formed by well-nourished stratum basal epithelial cells in the matrix. The farther away they get from the growing region, they become keratinized and die. • Consists of central core (medulla) surrounded by cortex layer, surrounded by a cuticle. • Cuticle provides strength, when it wears away, you get split ends.
Hair • Melanocytes determine hair color • Texture is determined by the shape of the hairshaft: • Oval hairshaft – smooth hair • Flat hairshaft- curly, kinky hair • Hair is all over the body with exception of palms of hands, soles of feet, lips • Hormones account for development of hairy regions such as armpits Arrectorpili- bands of smooth muscle connect to hair follicle and dermal tissue, when muscles contract they form “goose bumps”
Nails • Scalelike modification of epidermis- mostly nonliving material • They have a free edge, a body and a root, border is overlapped by skin folds. • Nails are transparent and nearly colorless but look pink due to rich blood supply in the dermis • White crescent is called LUNULA
Skin disorders • Skin can develop more than 1000 disorders with many causes • Athlete’s foot- fungus • Boils- staph infection-bacteria • Cold Sores- virus • Contact Dermatitis- chemicals, allergy • Impetigo- staph infection, very contagious, especially common in children • Psoriasis-unknown cause- red lesions covered with dry, silvery scales, can be disfiguring.
Burns • Tissue damage and cell death caused by heat, electricity, UV radiation and some chemicals. • Damages due to burns: • Body loses fluids as they seep from burned surfaces, dehydration and electrolyte imbalance follows. Can lead to kidney shutdown and circulatory shock. • Infection can set in after 24 hours and your immune system is weakened because of the burn.
Severity of Burns • 1st Degree- only epidermis is damaged. Red and swollen. Usually not that serious. • 2nd Degree- injures epidermis and upper region of dermis. Skin is red and painful, blisters appear. Regrowth of epithelium can occur. Usually no scars. • 3rd Degree- full thickness of skin burns, appears gray-white or blackened. Nerves are destroyed. Regeneration isn’t possible, must have skin graft. • Facial burns are dangerous when Respiratory pathways are effectedsince they can swell and cause suffocation.
Aging Aspects • Subcutaneous tissue decreases, intolerance to cold • Skin is drier • Skin is thinner- more likely to bruise • Lost elasticity- allows bags under eyes • Hair Loss- by 50, the number of hair follicles has dropped by 1/3 and continues to decline • Male pattern baldness is an obvious baldness that increases as you age
Aging • Graying- amount of melanin in hair decreases or becomes entirely absent. • Causes of graying or hair loss: • Anxiety • Protein deficient diet • Chemotherapy • Radiation • Excessive Vitamin A • Fungal disorders This is usually not permanent when it comes to hair loss.