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Explore how the rate of a reaction is determined by the unfolding and folding processes. Discover the key barriers affecting reaction kinetics and understand the impact of molecular transformations in this dynamic process.
E N D
‡ G D N
Unfolding process Folding process Rate is determined by this barrier Rate is determined by this barrier ‡ G D N
‡ ‡* G D, D* DGD - N DG*D - N N, N*
‡ DG‡ - D 1/kf G DG‡ - N 1/ku D DGD - N N
‡ ‡* DG*‡ - N DG*‡ - D DG‡ - D DG‡ - N G D D* DG*D - N N* DGD - N DDGD - N N
‡ ‡* DG‡ - D DG‡ - N G DG*‡ - D DG*‡ - N D, D* DDGD - N DGD - N DG*D - N N N*