prescribing in paediatric cystic fibrosis l.
Download
Skip this Video
Loading SlideShow in 5 Seconds..
PRESCRIBING IN PAEDIATRIC CYSTIC FIBROSIS PowerPoint Presentation
Download Presentation
PRESCRIBING IN PAEDIATRIC CYSTIC FIBROSIS

Loading in 2 Seconds...

play fullscreen
1 / 7

PRESCRIBING IN PAEDIATRIC CYSTIC FIBROSIS - PowerPoint PPT Presentation


  • 286 Views
  • Uploaded on

PRESCRIBING IN PAEDIATRIC CYSTIC FIBROSIS. The child will soon die, whose brow taste salty when kissed (18 th century). Commonest genetic disease in Europeans 5% of us are carriers 1 in 2,000 births. Biochemical defect in cystic fibrosis. Exocrine gland cell membrane. Cl -. Cl -. Cl -.

loader
I am the owner, or an agent authorized to act on behalf of the owner, of the copyrighted work described.
capcha
Download Presentation

PowerPoint Slideshow about 'PRESCRIBING IN PAEDIATRIC CYSTIC FIBROSIS' - ichabod


An Image/Link below is provided (as is) to download presentation

Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author.While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server.


- - - - - - - - - - - - - - - - - - - - - - - - - - E N D - - - - - - - - - - - - - - - - - - - - - - - - - -
Presentation Transcript
prescribing in paediatric cystic fibrosis

PRESCRIBING IN PAEDIATRIC CYSTIC FIBROSIS

Scottish Neonatal and Paediatric Pharmacists Group

the child will soon die whose brow taste salty when kissed 18 th century
The child will soon die, whose brow taste salty when kissed(18th century)
  • Commonest genetic disease in Europeans
  • 5% of us are carriers
  • 1 in 2,000 births

Scottish Neonatal and Paediatric Pharmacists Group

biochemical defect in cystic fibrosis
Biochemical defect in cystic fibrosis

Exocrine gland

cell membrane

Cl-

Cl-

Cl-

LUNGS

Thick

Viscous

Mucus

H2O

Cl-

Cl-

Cl-

H2O

Chloride

channel

H2O

Na+

Na+

Na+

Na+

Na+

Na+

Na+ pump

Scottish Neonatal and Paediatric Pharmacists Group

slide4
Defective chloride transport

ä

Problems with exocrine glands

ä

Sweat, lungs, pancreas

ä

Lung infections, GIT problems e.g. failure to thrive, malabsorption

Scottish Neonatal and Paediatric Pharmacists Group

lungs

Flucloxacillin

Co-Amoxiclav

Cetazidime

Gentamicin

Colistin

Teicoplanin

Lungs

S. AureusH. InfluenzaeP.Aeruginosa ( + Cepacia)

Drugs include:

Scottish Neonatal and Paediatric Pharmacists Group

slide6

{Protease

Lack of

{Lipase

{Amylase

Gut

Drugs include

Creon Pancrease Nutrizym

Vitamins (e.g. Vit E, Ketovite (tabs & liquid)

Dietary supplements

Scottish Neonatal and Paediatric Pharmacists Group

the future
The future
  • Dnase (Pulmozyme) for all
  • Home therapy
  • Amiloride
  • Heart/Lung transplant
  • Gene therapy

Scottish Neonatal and Paediatric Pharmacists Group