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BSC 2011 - 02

BSC 2011 - 02. Patterns of Inheritance. Developmental Biology. Evolution. Ecology. Some Important Definitions. Science - the investigation of rational concepts that can be evaluated by observations and experimentation. Hypothesis - a proposed explanation for an observed phenomenon

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BSC 2011 - 02

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  1. BSC 2011 - 02 Patterns of Inheritance Developmental Biology Evolution Ecology

  2. Some Important Definitions Science - the investigation of rational concepts that can be evaluated by observations and experimentation. Hypothesis - a proposed explanation for an observed phenomenon Theory - a hypothesis that is consistent with all available evidence

  3. Outline of Lecture 1 • I. THE CENTRAL DOGMA • A. DNA structure • B. DNA Replication • C. Chromosomes • 1. Prokaryotic • 2. Eukaryotic • D. RNA Structure • E. Transcription • 1. Summary • 2. Prokaryotes • 3. Eukaryotes • F. Translation • 1. The genetic code • 2. Summary of translation

  4. DNA structure A linear sequence of nucleotides Nucleotide Phosphate 5-C sugar Nitrogenous base Thymine Cytosine Guanine Adenine Fig 16.3

  5. Fig. 16.5 DNA Structure - the double helix

  6. Fig. 16.7 DNA Replication Catalyzed by DNA-polymerase

  7. Fig.1.4

  8. Chromosome numbers in Eukaryotes Chimps - 48 Humans - 46 Fruit fly 4 Onion - 8 Potato - ??

  9. Chromosome numbers in Eukaryotes Chimps - 48 Humans - 46 Fruit fly 4 Onion - 8 Potato - 48

  10. Fig. 17.6 Transcription Template strand - the single strand of DNA that is transcribed RNA polymerase - the enzyme that catalyzes the synthesis of RNA using DNA as the template Promoter - the segment of the DNA template strand where RNA polymerase binds and initiates transcription

  11. Fig. 17.6

  12. Fig. 17.6

  13. Fig. 17.6

  14. Fig. 17.8,17.9 RNA processing Poly-A- tail 5’ cap RNA splicing

  15. Fig. 17.4 The Genetic Code Codon - 3 base sequence that codes for one amino acid or is a signal.

  16. Fig. 17.13 Transfer RNA (tRNA)

  17. Fig. 17.12 Translation of mRNA into protein

  18. Fig. 17.25

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