1 / 32

Biomolecular Machines

Discover the intricate world of biomolecular machines with Dek Woolfson from the University of Sussex. Dive into transcription, translation, protein folding, and more. Learn about proteins behaving poorly, the Proteasome as a molecular ruler, and the F1F0 complex's rotary catalysis. Uncover the secrets of molecular turbines, sticky molecules like EPO, and the dynamic nature of haemoglobin. See how ATP is made and explore the human karyotype. Join us on this fascinating journey through the molecular landscapes of life sciences!

hnave
Download Presentation

Biomolecular Machines

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Biomolecular Machines Dek Woolfson University of Sussex Dek Woolfson, Biological Sciences, Sussex

  2. Dek Woolfson, Biological Sciences, Sussex

  3. Dek Woolfson, Biological Sciences, Sussex

  4. Transcription:getting fromDNA to RNA Dek Woolfson, Biological Sciences, Sussex

  5. Switching Genes On:Transcription Factors ≈2,300 atoms Dek Woolfson, Biological Sciences, Sussex

  6. Mad Max Dek Woolfson, Biological Sciences, Sussex

  7. Translation:getting fromRNA to protein Dek Woolfson, Biological Sciences, Sussex

  8. Making Proteins:Translation on the Ribosome Dek Woolfson, Biological Sciences, Sussex

  9. Protein Folding:getting proteinsinto shape Dek Woolfson, Biological Sciences, Sussex

  10. Folding Proteins:The GroE Chaperone Dek Woolfson, Biological Sciences, Sussex

  11. doing everything... Dek Woolfson, Biological Sciences, Sussex

  12. Sticky Molecules:EPO ≈3,500 atoms Dek Woolfson, Biological Sciences, Sussex

  13. Dynamic Molecules:Haemoglobin ≈4,400 atoms Dek Woolfson, Biological Sciences, Sussex

  14. Protein Misfolding:proteins behaving badly Dek Woolfson, Biological Sciences, Sussex

  15. Prions & Amyloid Dek Woolfson, Biological Sciences, Sussex

  16. Garbage Disposal:getting rid ofunwanted proteins Dek Woolfson, Biological Sciences, Sussex

  17. Recycling Proteins:The Proteasome ≈56,400 atoms Dek Woolfson, Biological Sciences, Sussex

  18. Dek Woolfson, Biological Sciences, Sussex

  19. The Proteasome as a molecular ruler Dek Woolfson, Biological Sciences, Sussex

  20. The Grim Reaper:ubiquitin Dek Woolfson, Biological Sciences, Sussex

  21. ≈600 atoms Dek Woolfson, Biological Sciences, Sussex

  22. Dek Woolfson, Biological Sciences, Sussex

  23. Dek Woolfson, Biological Sciences, Sussex

  24. Dek Woolfson, Biological Sciences, Sussex

  25. Finding the Energy:How ATP is made. Dek Woolfson, Biological Sciences, Sussex

  26. The F1F0 Complex Dek Woolfson, Biological Sciences, Sussex

  27. The F1 ATPase ≈23,000 atoms Dek Woolfson, Biological Sciences, Sussex

  28. The g-subunitacts as a crankshaft Dek Woolfson, Biological Sciences, Sussex

  29. Rotary Catalysis Dek Woolfson, Biological Sciences, Sussex

  30. The F0 component is in the membrane and acts as a molecular turbine Dek Woolfson, Biological Sciences, Sussex

  31. There’s plenty to do:human karyotype Dek Woolfson, Biological Sciences, Sussex

  32. Dek Woolfson, Biological Sciences, Sussex

More Related