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Biomolecular Machines

Biomolecular Machines. Dek Woolfson University of Sussex. Transcription: getting from DNA to RNA. Switching Genes On: Transcription Factors. ≈2,300 atoms. Mad Max. Translation: getting from RNA to protein. Making Proteins: Translation on the Ribosome.

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Biomolecular Machines

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  1. Biomolecular Machines Dek Woolfson University of Sussex Dek Woolfson, Biological Sciences, Sussex

  2. Dek Woolfson, Biological Sciences, Sussex

  3. Dek Woolfson, Biological Sciences, Sussex

  4. Transcription:getting fromDNA to RNA Dek Woolfson, Biological Sciences, Sussex

  5. Switching Genes On:Transcription Factors ≈2,300 atoms Dek Woolfson, Biological Sciences, Sussex

  6. Mad Max Dek Woolfson, Biological Sciences, Sussex

  7. Translation:getting fromRNA to protein Dek Woolfson, Biological Sciences, Sussex

  8. Making Proteins:Translation on the Ribosome Dek Woolfson, Biological Sciences, Sussex

  9. Protein Folding:getting proteinsinto shape Dek Woolfson, Biological Sciences, Sussex

  10. Folding Proteins:The GroE Chaperone Dek Woolfson, Biological Sciences, Sussex

  11. doing everything... Dek Woolfson, Biological Sciences, Sussex

  12. Sticky Molecules:EPO ≈3,500 atoms Dek Woolfson, Biological Sciences, Sussex

  13. Dynamic Molecules:Haemoglobin ≈4,400 atoms Dek Woolfson, Biological Sciences, Sussex

  14. Protein Misfolding:proteins behaving badly Dek Woolfson, Biological Sciences, Sussex

  15. Prions & Amyloid Dek Woolfson, Biological Sciences, Sussex

  16. Garbage Disposal:getting rid ofunwanted proteins Dek Woolfson, Biological Sciences, Sussex

  17. Recycling Proteins:The Proteasome ≈56,400 atoms Dek Woolfson, Biological Sciences, Sussex

  18. Dek Woolfson, Biological Sciences, Sussex

  19. The Proteasome as a molecular ruler Dek Woolfson, Biological Sciences, Sussex

  20. The Grim Reaper:ubiquitin Dek Woolfson, Biological Sciences, Sussex

  21. ≈600 atoms Dek Woolfson, Biological Sciences, Sussex

  22. Dek Woolfson, Biological Sciences, Sussex

  23. Dek Woolfson, Biological Sciences, Sussex

  24. Dek Woolfson, Biological Sciences, Sussex

  25. Finding the Energy:How ATP is made. Dek Woolfson, Biological Sciences, Sussex

  26. The F1F0 Complex Dek Woolfson, Biological Sciences, Sussex

  27. The F1 ATPase ≈23,000 atoms Dek Woolfson, Biological Sciences, Sussex

  28. The g-subunitacts as a crankshaft Dek Woolfson, Biological Sciences, Sussex

  29. Rotary Catalysis Dek Woolfson, Biological Sciences, Sussex

  30. The F0 component is in the membrane and acts as a molecular turbine Dek Woolfson, Biological Sciences, Sussex

  31. There’s plenty to do:human karyotype Dek Woolfson, Biological Sciences, Sussex

  32. Dek Woolfson, Biological Sciences, Sussex

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