1 / 1

IRF

TCR. CD3. CD3. LAT. LAT. g. PLC. LcK. Grb2. ZAP70. GRP1. Ptdlns(4,5)P2. SOS. Gads. Ins91,4,5)P3. SLP76. DAG. Ras. Vav. 2+. Ca. Raf. CISH. CISH. q. PKC. -. q. PKC. -. Rac. cdc42. Calcineurin. MEK. Rho. -. C. IKK. ERK. JNK. NF. -. AT. AP. -. 1. NF. -.

heman
Download Presentation

IRF

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. TCR CD3 CD3 LAT LAT g PLC LcK Grb2 ZAP70 GRP1 Ptdlns(4,5)P2 SOS Gads Ins91,4,5)P3 SLP76 DAG Ras Vav 2+ Ca Raf CISH CISH q PKC - q PKC - Rac cdc42 Calcineurin MEK Rho - C IKK ERK JNK NF - AT AP - 1 NF - B k IRF - 4 Oct - 1 Oct - 1 NF - B k AP - 1 NFAT AP - 1 AP - 1 NF - B NFAT k CREB - 300 - 60 B RIN2 RAB7 MAPK6 MAPK7 MAPK8 RAB6a PBMC Pre-Sort PBMC Pre-Sort RAS Cluster NF-kBp105/p50 NFAT-5 TANK rIL-2 No-Stim Oct-1 Calcineurin-a Gads NF-kBp100/p50B SOS LCP-2 CISH PKC- GRP-1 VAV Rho-C cluster Highly consistent cluster A

More Related