Health Chronical ARE PIPS SAFE FOR YOU
HEALTH CHRONICAL Side Effects of Omeprazole & Pantoprazole
INTRO:- In this article we will talk about how Proton Pump Inhibitors like Omeprazole, Esomeprazole and Pantoprazole have side effects. We will also talk about how the US Food and Drug administration limits the consumption of these drugs.
Have you ever heard of any of these drugs? • Omeprazole • Esomeprazole • Rabeprazole • Pantoprazole • Dexlansoprazole
Surprisingly, all of the above listed drugs belong to one category – Proton pump inhibitors (PPI). “Proton pump inhibitors (PPIs) are a group of drugs whose main action is a pronounced and long-lasting reduction of gastric acid production. Within the class of medications, there is no clear evidence that one agent works better than another”
Source: NCBI: They are prescribed mainly for treatment of the following symptoms: Acid reflux GERD Gastrointestinal disease Acidity Hiatal hernia
Now how helpful or harmful are these medicines REALLY? Lets start by listing down some well known side effects. High dose and/or long-term use of PPIs carries a possible increased risk of bone fractures. Source: USFDA Some studies have shown a correlation between use of PPIs and Clostridium difficile infections. Long-term use of PPIs is associated with the development of benign polyps PPI use has also been associated with the development of microscopic colitis. Source: oxford
Other common associations are: • Chronic kidney disease • Liver damage • Prostatomegaly • Imbalanced Lipid profile • PCOD