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Mia Botkin, MPH student Walden University PUBH-6165-5 Instructor: Dr. Raymond W. Thron

Toxicity of Aluminum. Mia Botkin, MPH student Walden University PUBH-6165-5 Instructor: Dr. Raymond W. Thron Environmental Health Winter, 2011. Learning Objectives. To address the toxicity of aluminum To address aluminum exposure level in our environment

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Mia Botkin, MPH student Walden University PUBH-6165-5 Instructor: Dr. Raymond W. Thron

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  1. Toxicity of Aluminum Mia Botkin, MPH student Walden University PUBH-6165-5 Instructor: Dr. Raymond W. Thron Environmental Health Winter, 2011

  2. Learning Objectives • To address the toxicity of aluminum • To address aluminum exposure level in our environment • To address aluminum affects on health • To educate and address matters of the regulation of aluminum safety

  3. What is Aluminum? • Most commonly exists and found in the earth’s crust. • A silvery white metal • Found in beverage cans, pans, airplanes, foils, buffered aspirin, and cosmetics (Agency for Toxic Substances & Disease Registry [ATSDR], 2010). http://www.numkitchen.com/ http://ningbogas.en.made-in-china.com/ ATSDR. (2010). Toxic substances portal – Aluminum. Retrieved on January 16, 2011 from http://www.atsdr.cdc.gov/toxfaqs/tf.asp?id=190&tid=34

  4. What is Aluminum? • Exist in combination with other chemicals (For example, oxygen, fluorine, and silicon) • Exposure – food, air, water, and soil • Cannot be broken down in the environment • Small fragments bind to other particles • The average U.S. adult eats average 8 mg/day ATSDR. (2010). Toxic substances portal – Aluminum. Retrieved on January 16, 2011 from http://www.atsdr.cdc.gov/toxfaqs/tf.asp?id=190&tid=34

  5. Our Environment Responses to Aluminum • Fluffy aluminum at mine areas drains into streams or rivers, and becomes solid matter, which poisons fish, animals, and plants (Alder, 2003). • The levels of aluminum in tea leaves are 10 -15 times greater than levels in the drinking water (ATSDR, 2008). Adler, T. (2003). Aluminum floc formation. Environmental Health Prospectives, 111(3), a147. doi:10.1289/ehp.111-a147a. ATSDR. (2008). Toxicological profile for aluminum. Retrieved on January 18, 2011 from www.atsdr.cdc.gov/HAC/pha/.../HalacoEngineeringPHAFinal01-21-2010.pdf

  6. EPA National Priorities List Sites with Aluminum Contamination CDC. (2010). Toxic substances portal-Aluminum. Retrieved on January 18, 2010 from http://www.atsdr.cdcgov/ToxProfiles/TP.asp?id=191&tid=34

  7. Our Body’s Responses to Aluminum Excessive exposure causes health problems: • Respiratory system –cough, shortness of breath • Neurological system – Alzheimer’s disease • Skeletal system - • Delays development of bone and nerve structure in the unborn • Generates kidney problem in children – further develops bone disease ATSDR. (2010). Toxic substances portal– Aluminum. 3.Health effects. Retrieved on January 16, 2011 from http://www.atsdr.cdc.gov/toxfaqs/tf.asp?id=190&tid=34

  8. Our Body’s Responses to Aluminum • May added in: • Flour • Baking soda • Coloring agents • Anticaking agents • Found in: • Breast milk from 0.0092 – 0.049 mg/L • Soy-based infant formula from 0.46 – 0.93 mg/L http://www.examiner.com/dogs-in-denver/dog-food-101-what-are-coloring-agents-aka-artificial-colors-color-additives http://hbbase.com/wp-content/uploads/305.jpg http://www.livestrong.com/article/116353-dangers-soy-infant-formula/ ATSDR. (2008). Toxicological profile for aluminum. Retrieved on February 6, 2011 from www.atsdr.cdc.gov/HAC/pha/.../HalacoEngineeringPHAFinal01-21-2010.pdf

  9. CDC. (2008a). Asbestosis United States: Asbestosis. Retrieved on January 17, 2011 from www.cdc.gov/niosh/docs/96-134/pdfs/96-134c.pdf

  10. CDC. (2008b). Data from the bureau of labor statistics. Retrieved on January 18, 2011 from www.cdc.gov/niosh/pdfs/2001-120.pdf

  11. Regulations The California Safe Drinking Water Act of 1996 (Adler, 2003) The National Environmental Policy Act of 1969 (Federal Register, 2003) Adler, T. (2003). Aluminum floc formation. Environmental Health Prospectives, 111(3), a147. doi:10.1289/ehp.111-a147. Federal Register. (2003). Hazardous materials regulations: Aluminum cylinder manufactured of aluminum alloy 6351-T6 used in SCUBA, SCBA, and oxygen service-revised requalification and use criteria. Retrieved on January 18, 2011 from http://www.federalregister.gov/articles/2003/09/10/03-22808/hazardous-materials-regulations-aluminum-cylinders-manufactured-of-aluminum-alloy-6351-t6-used-in

  12. Contaminant Levels of Aluminum Recommendations by the Occupational Health and Safely Administration (OSHA): • Worker’s permissible dust in air exposure limit - 15mg/m3 in a total dust • Accumulative exposure in the air over a 40 hours of work per week – 5 mg/m3 (OSHA, n. d.). OSHA. (n.d.). Occupational safety and health guideline for aluminum. Retrieved on January 17, 2011 from http://www.osha.gov/SLTC/healthguidelines/aluminum/recognition.html

  13. Contaminant Levels of Aluminum • U.S. Food and Drug Administration (FDA) regulation: • In bottled water – 0.2 mg/L for aluminum (Department of Health and Human Service [DHHS],1995) • Recommendations by Environmental Protection Agency (EPA): • In drinking water: 0.05 - 0.2 mg/L(EPA, 2011) • DHHS. (1995). Beverages; Bottled water; proposed rules. Federal Register (Docket No. QSN-9203). 60 (218), 57131- 57133. • EPA. (2011).Drinking water contaminants: National primary drinking water regulations. Retrieved on January 17, 2011 from http://water.epa.gov/drink/contaminants/index.cfm

  14. Conclusions • Aluminum is most abundant in the earth surface and ground. • Aluminum can be found anywhere in water, food, and soil. • Aluminum creates malfunctions of the human body. • Federal government enacts Contaminant levels for aluminum.

  15. Doyou have any questions? Thank you!!!

  16. References Adler, T. (2003). Aluminum floc formation. Environmental Health Prospectives, 111(3), a147. doi:10.1289/ehp.111-a147a. ATSDR. (2010). Toxic substances portal – Aluminum. Retrieved on January 16, 2011 from http://www.atsdr.cdc.gov/toxfaqs/tf.asp?id=190&tid=34 ATSDR. (2008). Toxicological profile for aluminum. Retrieved on January 18, 2011 from www.atsdr.cdc.gov/HAC/pha/.../HalacoEngineeringPHAFinal01-21-2010.pdf CDC. (2008a). Asbestosis United States: Asbestosis. Retrieved on January 17, 2011 from www.cdc.gov/niosh/docs/96-134/pdfs/96-134c.pdf CDC. (2008b). Data from the bureau of labor statistics. Retrieved on January 18, 2011 from www.cdc.gov/niosh/pdfs/2001-120.pdf. CDC. (2010). Toxic substances portal-Aluminum. Retrieved on January 18, 2010 from http://www.atsdr.cdcgov/ToxProfiles/TP.asp?id=191&tid=34

  17. References (cont…) DHHS. (1995). Federal and Administration - Beverages; Bottled water; proposed rules. Federal Register (Docket No. QSN-9203). 60 (218), 57131- 57133. EPA. (2011). Drinking water contaminants: National primary drinking water regulations. Retrieved on January 17, 2011 from http://water.epa.gov/drink/contaminants/index.cfm. Federal Register. (2003). Hazardous materials regulations: Aluminum cylinder manufactured of aluminum alloy 6351-T6 used in SCUBA, SCBA, and oxygen service-revised requalification and use criteria. Retrieved on January 18, 2011 from http://www.federalregister.gov/articles/2003/09/10/03-22808/hazardous-materials-regulations-aluminum-cylinders-manufactured-of-aluminum-alloy-6351-t6-used-in. OSHA. (n.d). Occupational safety and health guideline for aluminum. Retrieved on January 17, 2011 from http://www.osha.gov/SLTC/healthguidelines/aluminum/recognition.html.

  18. FurtherReadingSources Agency for Toxic Substances & Disease Registry. (2010). Toxic substances portal-Aluminum. Retrieved on February 6, 2011 from http://www.atsdr.cdc.gov/toxfaqs/tf.asp?id=190&tid=34 OSHA. (n.d). Occupational safety and health guideline for aluminum. Retrieved on January 17, 2011 from http://www.osha.gov/SLTC/healthguidelines/aluminum/recognition.html. Yellamma, K., Saraswathamma, S., & Nirmala Kumari, B. (2011). Cholinergic System Under Aluminum Toxicity in Rat Brain. International Journal of Toxicology, 17(2), 106-112. Retrieved on January 16, 2011 from http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2997452/?tool=pubmed

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