EXPLORING DEAD GENES. Adrienne Manuel I400. What are they?. Dead Genes are also called Pseudogenes Pseudogenes are non functioning copies of genes in DNA Results from reverse transcription from an mRNA transcript Or from gene duplication and subsequent disablement.
DEFINING POPULATIONS AND SUBPOPULATIONS
Step 1: Sanger centre pseudogene annotations
Step 2: FASTA matching to find potential pseudogenes
Step 3: reduction for overlaps on the genomic DNA
Step 4: Prevention of over counting for adjacent matches.
Step 5: Masking against Sanger Centre annotation and Transposon library.
Step 6: Reduction for possible additional repeat elements
Step 7: reducing threshold stringency
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