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September 14, 2010 Pierce Hall

McLean Hospital Research Town Meeting. September 14, 2010 Pierce Hall. McLean Research: Town Meeting Agenda. General Announcements Announcement: New Division Portfolio Management Grant Administration Competencies Q&A / Open Forum Cataldo Mentoring Award Presentation Reception.

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September 14, 2010 Pierce Hall

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  1. McLean Hospital Research Town Meeting September 14, 2010 Pierce Hall

  2. McLean Research: Town Meeting Agenda • General Announcements • Announcement: New Division • Portfolio Management • Grant Administration Competencies • Q&A / Open Forum • Cataldo Mentoring Award Presentation • Reception

  3. McLean Research: General Announcements • Effort Reporting • InSight - New Fund Balance Statements • Faculty / Post-doc Review Templates • McLean Research Intranet Added Feature: • “Feedback / How Can We Help?” • McLean Research Day • Thursday, January 13th, 2011, 1:00 - 5:30 p.m.

  4. New Division Division of Basic Neuroscience Chief: Joseph T. Coyle, MD (Effective October 1, 2010)

  5. New Federal Grants since January 1, 2010 S. Andersen: R01 Early drug exposure and drug reward mechanisms D. Balu: F32 Molecular Mechanisms of Dendritic Abnormalities Related to D-Serine Deficiency V. Bolshakov: R01 Synaptic mechanisms in extinction of conditioned fear V. Bolshakov: R03 Functional role of vesicular zinc in synaptic mechanisms in the amygdale E. Chartoff: R01 Role of dopamine signaling in the mood-related effects of salvinorin A M. Copersino: K23 Multimodal Brain Imaging of Functional Neurodyynamics in Cocaine Dependence B. Frederick: S10 4 Tesla MR Spectroscopy Console Upgrade

  6. New Federal Grants since January 1, 2010 B. Frederick: R21 Real time near infrared spectroscopy of the frontal lobe for Neurofeedback M. Hall: K01 Functional Characterization of Risk Variants for Psychotic Illness in the GWA Er E. Jensen: R21 Proton Echo-Planar Spectroscopic Imaging of GABA, Glutamate/Glutamine at 4 Tesla R. Karmacharya: K08 Wnt/GSK3/ beta-CateninSingaling as a Target for Treatment of Bipolar Disorder K. Kim: R01 Protein-induced human iPS cells for personalized cell therapy for PD N. Mello: R01 Sex/gender and nicotine addiction: hormones, behavior and neuroimaging K. Myers: K01 NMDA receptor-mediated plasticity in extinction of conditioned opiate withdrawal

  7. New Federal Grants since January 1, 2010 G. Noam: NSF Empirical- Development of an Observation Tool for the Informal Science Field U. Rudolph: R21 Generation of etiological models for schizophrenia by chromosome engineering M. Silveri: R01 Neurobiological consequences of binge alcohol consumption in young adults M. Silveri: R21 Sex Differences and Alcohol Dependence: Hippocampal Neurochemistry and Function M. Teicher: R01 Sensitive Periods, Brain Development and Depression M. Thomsen: K99 Elective muscarinic receptor ligands as targets for cocaine addiction medication

  8. McLean Research Research Portfolio Management

  9. McLean Research: Portfolio Management In order to enhance research portfolio management and to reduce research fund deficits: • Enhance financial reports, tools and oversight processes for improved fund management and more accurate and timely identification of fund in deficit and at imminent risk of deficit • Update, communicate and ensure compliance with policies and procedures • Improve communication between Research Administration and McLean research community • Expand support of researchers

  10. McLean Research: Portfolio Management • Enhance financial reports, tools and oversight processes for improved portfolio and fund management and more accurate and timely identification of fund in deficit and at imminent risk of deficit • Reports for McLean PIs, Research Administration and Finance • Insight financial reports • InfoEd – Proposal Tracking; Proposal Development • Re-mapping of Chief of Service codes • Processes • Resource projections annually by lab • Regularly recurring tracking of fund balances and burn rates by Research Administration and Finance • Early warning to PIs as needed

  11. Research Fund Management Initiative • Update, communicate and ensure compliance with policies and procedures • Review, clarify and update policies and procedures • Simplify when possible • Develop manual that includes: • Detailed responsibilities of PI, lab-based research administrators and Research Administration • Checklists for PIs and grant managers • Procedure flow charts • Organizational chart • Provide contacts who can offer support and guidance • Make information more easily accessible • Research Intranet (research.mclean.harvard.edu)

  12. Research Fund Management Initiative • Improve communication between Research Administration and McLean research community Optimize use of modes of communication • Research Intranet • Email • Departmental Research Administrators Workgroup (DRAW) • Research Committee • Mailman Research Center Steering Committee • Research Town Meeting

  13. Research Fund Management Initiative • Expand support of researchers • Continue Research Admin open door policy for PIs and administrators in addition to regular office hours for: • Pre-award • Time and effort reporting • Post-award • Research Finance • Portfolio management • Enhance training • New PIs • Lab-based research administrators • General research community

  14. McLean Research Grant Oversight Grant Administration Competencies

  15. McLean Research Goal: Ensure that all PI’s and research grant administrators at McLean Hospital have requisite knowledge and skills to manage their grants. • Advisory Committees: • DA’s (DA’s and PI’s) • PI’s (PI’s) • Training • Assessment and feedback

  16. McLean Research Changing Research Landscape: • Increasing complexity of federal regulations • Public demand for research accountability / transparency • Significant audits / settlements • Greater scrutiny • Effort reporting • Cost Allocation • Cost transfers • Unallowable costs • Subrecipient monitoring • Delinquent reporting to sponsor

  17. McLean Research Principal Investigators: • Roles and Responsibilities • Scientific Integrity • Effort and Salary • Financial Oversight • Conflict of Interest http://phsresearchintranet.partners.org/PHS_ResearchMgmt/PHSResearchCompliance-PIQuickGuide.asp

  18. McLean Research Department Administrators: • Roles and Responsibilities • Pre-Award, Progress Report Documents • Subcontracts • Allowable Costs • Income & Expense • Effort Reporting http://phsresearchintranet.partners.org/PHS_ResearchMgmt/PHSResearchCompliance-DAQuickGuide.asp

  19. McLean Research Questions Open Forum

  20. McLean Research Presentation 2010 Anne M. Cataldo Excellence in Mentoring Award to Ross J. Baldessarini, MD

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