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Chamazulene, extracted from chamomile flowers, is an anti-inflammatory compound that blocks the enzyme 5-lipoxygenase, disrupting leukotriene biosynthesis. This molecule is part of the C10 bicyclic azulene ring system and exhibits aromatic properties with 4n+2 electrons in a planar cycle of p-orbitals.
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Chamazulene, 1,4-dimethyl-7-ethylazulene, is extracted from chamomile flowers. It is an anti-inflammatory by virtue of its ability to block the activity of the enzyme 5-lipoxygenase. This interferes with the biosynthsis of leukotrienes, a class of molecules that have an important role in inflammatory responses arising from allergies and asthma. Chamazulene contains the C10 bicyclic azulene ring system. With 4n+2 electrons in an uninterrupted planar cycle of p-ortibals it is an aromatic molecule. cc license image Roni G, Flickr
