http://www.bcm.edu/labs/davis/researchprojects.htm http://www.jpp.krakow.pl/journal/archive/1203_s4/gfx/rys16_2.jpg Alcohol has the largest death rate out of all other drugs disorders caused by alcohol have increased over the past 6 years Olfactory training http://www.northwestern.edu/neurobiology/faculty/allada2/gbbpapers/MooreHeberlein98.pdf Need Knowledge Base Short Term Memory Alcohol Literature Review Control and chpd Comparison between Control and chpd Drosophila Moore, 98 Holly LaFerriere 2007 Purpose Hypothesis The purpose of this experiment is to demonstrate the effects of alcohol exposure on short term memory in drosophila. Null Hypothesis: the ethanol exposure will have no effect on the short term memory of Drosophila melanogaster. Alternate Hypothesis: the Drosophila exposed to ethanol will have impaired short term memory, and the Drosophila who are not, will not
Wild Type Drosophila Alcohol Before Alcohol After Control Trained in olfactory method with one minute shock increments every 10 minutes Exposed to Alcohol for 5 minutes Trained in olfactory method with one minute shock increments every 10 minutes Trained in olfactory method with one minute shock increments every 10 minutes Exposed to Alcohol for 5 minutes Methodology Tested 5 hours later Tested 5 hours later Tested 5 hours later Training Chamber Testing Chamber Results
Alcohol Exposure Ethanol beaker Air pump Exposure chamber Discussion The purpose of this experiment is to demonstrate the effects of alcohol exposure on short term memory in drosophila. Results demonstrated that exposure to alcohol impaired short term memory Performance Index: (Correct-Incorrect)-.5/.5 x100 Limitations Conclusion The number of trials for drosophila exposed to alcohol could have been higher and possible human errors. Data Supported the Alternate Hypothesis Future Studies Effects of alcohol on long term memory. Bibliography Bayard, Max. "Alcohol Withdrawal Syndrome - March 15, 2004 - American Family Physician." American Academy of Family Physicians. 2004. 25 May 2009 <http://www.aafp.org/afp/20040315/1443.html>. Ericson, Nels. "Substance Abuse:The Nation’s Number One Health Problem." 2001. U.S. Department of Justice. <http://www.ncjrs.gov/pdffiles1/ojjdp/fs200117.pdf>. Farr, Susan. "Drinking for just eight weeks impairs learning and memory in mice." Science, Industry and Business: the innovations-report. 15 May 2009 <http://www.innovations-report.com/html/reports/life_sciences/report-45402.html>. Grant B, Harford TC, Dawson DA, et al. Prevalence of DSM-IV alcohol abuse and dependence, United States 1992. Alcohol Health & Research World 18(3). 1994. Laferriere, Holly, and Douglas J. Guarnieri. "Genetic Dissociation of Ethanol Sensitivity and Memory Formation in Drosophila melanogaster." (2008). Genetics. <http://www.genetics.org/cgi/content/full/178/4/1895/>. Miller, Loren L., and Michael P. Dolan. "SpringerLink - Journal Article." SpringerLink Home - Main. 1973. <http://www.springerlink.com/content/u0161w1781274g83/>. Moore, Monica, and Jim DeZazzo. "Ethanol Intoxication in Drosophila:Genetic and Pharmacological Evidence for Regulation by the cAMP Signaling Pathway." (1998). <http://www.northwestern.edu/neurobiology/faculty/allada2/gbbpapers/MooreHeberlein98.pdf>.