Grand Ward Rounds - 20/3/2008 -. - Dr Angeline Yong. Case 1. 46/Chinese/Female Factory worker No PMHx of note Presented on 25/2/2008 with C/o: Intermittent BOV over LE x 6/12 - generalised darkening of vision during attacks lasting a few seconds - no neurological deficits
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- Dr Angeline Yong
OS: Patchy non-specific losses,
enlarged blind spot
Several other disease processes have a propensity for involving the dura or subdural space resulting in an appearance that may suggest meningioma. These include:
stroke - 5% (because of ICA invasion)
pituitary dysfunction - 1%
death - 1%
Major complications incl infection/ bleeding = 15%
1. Radhakrishnan, D, Mokri, et al. The trends in incidence of primary brain tuors in the population of Rochester, minnesota. Ann. Neurol 1995; 37:67
2. Longstreth, WTJr, et al. epidemiology of intracranial meningioma. Cancer 1993; 72:639.
3. Whittle, IR, Smith, et al. Meningiomas. Lancet 2004; 363:1535.
Focal findings -
Characteristic focal deficits are caused by tumors in
though often unrecognised, are common in meningiomas.
2. Hearing loss -
cerebellopontine angle meningiomas can produce SNHL.
3. Mental status changes -
neglect/inattention may result from large subfrontal/sphenoid
4. Extremity weakness -
parasagittal meningiomas growing on the falx against the motor
strip can lead to bilat. Leg weakness.
5. Obstructive hydrocephalus -
Large tumors in the posterior cranial fossa can cause
obstructive hydrocephalus and present with papilledema and
early morning headache
In one series of 80 patients, approximately 1/3 had ophthalmologic symptoms including visual field loss, field defects, and diplopia.4
4. Anderson, D, Khalil, M. Meningioma and the ophthalmologist. A review of 80 cases. Ophtahalmology 1981; 88:1004