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http://www.aasraw.com/products/prilocaine/ - Prilocaine is a local anesthetic(prilocaine local anesthetia)of the amino amide type,In its injectable form , it is often used in dentistry.\n

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how long does prilocaine last aasraw prilocaine

How long does prilocaine last?-AASraw(prilocaine powder supplier)

www.aasraw.com aas15@aasraw.com

1. What is prilocaine?

Prilocaine is a local anesthetic(prilocaine local anesthetia)of the amino amide type

first prepared by Claes Tegner and Nils Löfgren. In its injectable form , it is often

used in dentistry. It is also often combined with lidocaine as a topical preparation for

dermal anesthesia , for treatment of conditions like paresthesia. As it has low cardiac

toxicity, it is commonly used for intravenous regional anaesthesia (IVRA).

2. Raw material of prilocaine

Raw material of prilocaine is the main ingredient for making prilocaine injectable

form or prilocaine cream form. Prilocaine powder is white crystalline

powder, Prilocaine powder/prilocaine local anethetia is chemically designated as

propanamide, N-(2-methylphenyl)-2-(propylamino), has an octanol: water partition

ratio of 25 at pH 7.4, and has the following characteristic:

prilocaine local anesthetic description

prilocaine

721-50-6

99%

white crystalline powder

C13H20N2O

220.31

37-38℃

RT

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Name

CAS No.

Purity

Apperance

Molecular Formula

Molecular Weight

Melt Point

Storage Temp

Manufacturer

Package

Payment method

Delivery

how long does prilocaine last aasraw prilocaine 1

How long does prilocaine last?-AASraw(prilocaine powder supplier)

www.aasraw.com aas15@aasraw.com

3. Prilocaine injection form and Prilocaine cream form?

Prilocaine injection form

Prilocaine Injection form,is a sterile, non pyrogenic isotonic solution that contains a

local anesthetic agent and is administered parenterally by injection. Prilocaine

Injection, contains prilocaine raw powder, which is chemically designated as

propanamide, N-(2-methyl-phenyl) -2- (propylamino)-, monohydrochloride.

Prilocaine stabilizes the neuronal membrane by inhibiting the ionic fluxes required for

the initiation and conduction of impulses, thereby effecting local anesthetic action.

prilocaine dosage:

how long does prilocaine last aasraw prilocaine 2

How long does prilocaine last?-AASraw(prilocaine powder supplier)

www.aasraw.com aas15@aasraw.com

Adult:

Maxillary infiltration: initially 1–2mL; max recommended dose within a 2-hour

period: <70kg: 8mg/kg; ≥70kg: 600mg. Elderly, debilitated, acutely ill: reduce dose.

Children:

<10yrs: use Clarks rule to calculate dose.

Contraindications:

Congenital or idiopathic methemoglobinemia.

Interactions: Risk of methemoglobinemia with sulfonamides, acetaminophen,

acetanilid, aniline dyes, benzocaine, chloroquine, dapsone, naphthalene, nitrates and

nitrites, nitrofurantoin, nitroglycerin, nitroprusside, pamaquine, para-aminosalicylic

acid, phenacetin, phenobarbital, phenytoin, primaquine, quinine.

Prilocaine cream form

Prilocaine cream form is an emulsion in which the oil phase is a eutectic mixture of

lidocaine powder and prilocaine powder in a ratio of 1:1 by weight. This eutectic

mixture has a melting point below room temperature and therefore both local

anesthetics exist as a liquid oil rather than as crystals. It is packaged in 5 gram and 30

gram tubes.

Lidocaine-Prilocaine cream contains lidocaine powder 25 mg, prilocaine raw powder

25 mg, polyoxyethylene fatty acid esters (as emulsifiers), carboxypolymethylene (as a

thickening agent), sodium hydroxide to adjust to a pH approximating 9, and purified

water to 1 gram. Llidocaine-prilocaine Cream contains no preservative, however it

passes the USP antimicrobial effectiveness test due to the pH. The specific gravity of

EMLA (lidocaine and prilocaine) Cream is 1.00.

4. How long does prilocaine last?

Excellent skin numbing results are obtained 30 minutes to 1 hour post application.

Don't be impatient: give the product time to work! That way, you obtain the most

benefit out of it.

Please don't fall for other products that promise "instant numbing". Unless the skin is

broken, is not going to happen.

That said, some areas of the body numb faster than others. For example, if you put

some of the gel on your lips (the red part), you will feel numb - really numb - in less

how long does prilocaine last aasraw prilocaine 3

How long does prilocaine last?-AASraw(prilocaine powder supplier)

www.aasraw.com aas15@aasraw.com

than ten minutes. That is because the skin there is very permeable. Try it yourself,

once you get the product, and you will believe it!

However, most other areas of the body take more time, because the skin elsewhere is

thicker, with many keratinized layers that act as a barrier.

TOPICAINE® is formulated to overcome this barrier, because it contains skin

permeation enhancers. These are substances that temporarily and reversibly increase

the permeability of the stratum corneum - the skin barrier.

In addition, the product needs some time to penetrate to where the pain receptors are

located, deep into the dermis. In some areas, like the lips, the numbing action can be

felt much faster because the nerve receptors are located very superficially. Most other

locations of the body the receptors are located deeper, and it takes longer to reach

them.

If the application time is 30 minutes, the skin numbing effect will last approximately

1 hour. If you apply the product for 1 hour, your skin will remain numb for about 2

hours, even after you remove it!

As a rule of thumb, remember this:

the duration of the numbing is about twice as long as the application time, and

the longer the application time, the longer and deeper the numbing effect

5. Prilocaine brand name

Prilocaine injection form: Citanest

Prilocaine cream form: Emla

6. Prilocaine side effects

The serious prilocaine side effects may include:

severe burning, stinging, or sensitivity where the medicine is applied;

swelling or redness;

sudden dizziness or sleepiness after medicine is applied;

bruising or purple appearance of the skin; or

unusual sensations of...

how long does prilocaine last aasraw prilocaine 4

How long does prilocaine last?-AASraw(prilocaine powder supplier)

www.aasraw.com aas15@aasraw.com

7. Buy prilocaine powder online from prilocaine powder

supplier-AASraw

AASraw is a professional manufacturer that provide high quality steroids raw material,

sex hormone, fat loss hormone, local anesthetic. As prilocaine powder supplier,

AASraw guarantee all the powder purity no less than 98%, with competitive price and

safely delivery.