Organic chemistry II lab 144phs 2013. Lab 1. Electrophilic Substitution. Electrophilic Substitution. Chemical reactions in which an electrophile displaces a group in a compound, typically but not always hydrogen. Electrophilic substitution. E lectrophile?
Chemical reactions in which an electrophile displaces a group in a compound, typically but not always hydrogen.
An electrophile is an atom, ion, molecule or even a compound that has an affinity for electrons, meaning that it is tending to become negatively charged. It act as electronacceptors during a chemical reaction to make a new covalent bond
Is reaction in which an electrophile replace one of the hydrogen atoms of the ring.
Step 1(key step)
The proton is removed by any of the bases, for example by the anion derived from the electrophile
Benzene sulfonic acid
The nitronium ion is the actual electrophile in nitration ; it reacts with benzene to form a resonance-stabilized arenium ion
The arenium ion then loses a proton to a Lewis base and becomes nitrobenzene