Acute HIV Follow-Up in NC Presented by. Muhammad “Maxi” Mackalo, DIS. Background of ACUTE HIV. STAT: Screening and Testing for Active Transmission The program has been operating since 2002
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Muhammad “Maxi” Mackalo, DIS
STAT: Screening and Testing for Active Transmission
The program has been operating since 2002
Dr Leone, Medical Director, Communicable Disease Branch is one of the co-founders of the study and is currently superheading the program operation
Tests are analyze at state-funded public health virology & serology laboratory;
Serum specimen are tested using a method called pooling & nucleic-acid testing using ultrasensitive HIV RNA RT-PCR test;
Results obtained are confirmed using WB;
In 2002, 4.9 cases per 10,000 clients were identified as a case
Acute Retroviral syndrome (Mostly Flu-like symptoms) such as:
Fever, rash, headache, night sweats, fatigue, malaise, athralgia, myalgia, pharyngitis, swollen lymph nodes, weight Loss (~ 6 lbs. or more), loss of appetite, oral ulcers, nausea, vomiting and diarrhea
Unprotected receptive & insertive anal sex;
The sharing of IV drug paraphernalia ;
Unprotected vaginal sex;
Receptive oral sex with a male partner;
Exposure to HIV/AIDS via any exchange of bodily fluids (ex: needle stick) .
All clients with (-) EIA (+) NAAT results, as well as EIA (+) WB (-) or Indeterminate with a (+) NAAT need to be followed by DIS for notification, counseling, interview & repeat HIV serology for confirmation of HIV infection
Clients with a (-) HIV antibody test within the previous month followed by (+) EIA/WB test are also identified as acute HIV cases
Persons identified with acute HIV are offered immediate access to care via the Acute HIV Program @ UNC
Statewide network of providers
Medical Evaluation and assessment by a clinician familiar with acute HIV infection
Receive information about HIV & acute HIV infection
Financial, social & psychological assistance available
Discuss concern(s) with diagnosis and treatment
Provide information for care options and applicable research opportunities
Locate, Notify, Counsel, Interview, and draw repeat specimen
Transport to first medical visit
Contact tracing for partners & suspects within 72 hours
Schedule follow up visits within a week after interview with all clients
Additional STAT research program -
1. Obtain consent to allow initial blood samples to go to UNC for testing
2. HIPAA release form to discuss sexual -social networks for state epidemiology and outbreak information
Many thanks to the following in preparation of this presentation:
Todd Vanhoy: NC Field Service Mgr.
Rhonda Ashby: Asst. Field Service Mgr.
Dr. Peter Leone: NC Medical Director, Communicable Disease Branch
Joann Kuruc: Acute HIV Program Mgr.