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Social Entrepreneurship. September 2010 Harvard Business Review. “If you’re not thinking about [social entrepreneurial] collaboration, you’ll soon be guilty of strategy malpractice.”. F our Keys to Building a Successful Social Entrepreneurial Organization. Four Keys.

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slide3

September 2010

Harvard Business Review

“If you’re not thinking about [social entrepreneurial] collaboration, you’ll soon be guilty of strategy malpractice.”

four keys
Four Keys

#1 Take on a Global Problem

#2 Create an Innovative New Solution

#3 Tap into the Passion of the Public

#4 Find New Ways to Fairly Compensate Participants

slide7

Classic Malnutrition

“Malnutrition kills five million children under the age of five each year in developing countries.”

– UNICEF

“Between one-third to one-half of all childhood deaths in the world are linked to malnutrition.”

– New York Times

malnutrition is now a global epidemic
Malnutrition is Now a Global Epidemic

Malnutrition affects more than 925 million people globally. In developed countries it is under diagnosed and undertreated because it is largely unrecognizable.

the new hidden hunger
The New “Hidden Hunger”

What might these two kids have in common?

Both could be dramatically undernourished.

micronutrient deficiency a missing link in overweight children
Micronutrient DeficiencyA Missing Link in Overweight Children

Study shows that odds of being overweight or obese were 80.8% higher for children deficient in essential vitamins and minerals.

JAAIM, Fall 2010

unhealthy eating and physical inactivity
Unhealthy Eating and Physical Inactivity
  • Is the leading cause of death in the U.S. – Up to 580,000 deaths per year.
  • Is a major cause of disability in seniors.
  • Is linked to about 75% of total health care costs.
nutritional fact
Nutritional Fact

Approximately 90% of the money Americans spend on food is used to buy processed food.

U.S. Department of Commerce, 1999

slide13

“A lot of what we see in the supermarket I would argue is not really food. It’s what I call edible, food-like substances.”

Documentary Food, Inc.

slide15
Fruits, Veggies Not as Vitamin-Rich as in Past, Says New Data

Larger Fruits and Vegetables Mean More Plentiful but Less Potent Bounty

By MEGAN CARPENTER

March 1, 2006 —Fruits and veggies aren't what they used to be, new data suggests.

Of the 13 major nutrients found in fruits and vegetables, six have declined substantially, according to a study by Donald Davis, a biochemist at the University of Texas at Austin.

Using data from the U.S. Department of Agriculture, Davis concludes that recently grown crops have shown decreases of up to 38 percent in protein, calcium, vitamin C, phosphorus, iron and riboflavin when compared with produce from past decades.

What accounts for this negative trend? Like any other competitive industry, farmers' attempts to drive up profits have led them to use new techniques to increase production, Davis said. The faster-grown fruits don't have as much time to develop the nutrients.

"Farmers get paid by the weight of a crop, not by amount of nutrients," Davis said. He called this the "dilution effect": As fruits and vegetables grown in the United States become larger and more plentiful, they provide fewer vitamins and minerals.

slide16

“It’s as though the food industry and the medical industry are conspiring against the consumer.”

Commercial Farming

Industry

that profits from growing fruits and

vegetables bigger and faster

Processed Food

Industry

that profits from making

inexpensive “food-like substances”

Poor Health

Pharmaceutical Industry

that profits from the management of poor health

associated with poor nutrition

slide17

For the First Time in Over 100 Years

The life expectancy of U.S. kids might actually

decline, according to a 2005 study published in

The New England Journal of Medicine.

2 create an innovative new solution to a global problem because what we re doing is not working
#2 Create an Innovative New Solution to a Global Problem Because What We’re Doing is Not Working
innovative solution
Innovative Solution

Mannatech has Developed and Patented

Real Food Technology® Solutions

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Foods are comprised of synergistic blends of various nutrients bound together into what’s called the food matrix.

It is the food matrix, not its individual nutritional constituents, that best supports human biological processes.

Nutrition Reviews, Vol. 65, No. 10

October 2007

slide21

Standardized Nutrient Sources

What do people really want?

Plant-Sourced

Synthetically Made

vitamin facts
Vitamins originate primarily from plant tissues

Synthetically made vitamins are not the same

Bioavailability of natural food complex vitamins is better than most synthetically made vitamins

Medical Hypothesis (2000) 55 (6) 461-469

Vitamin Facts
synthetic vitamin studies
Synthetic Vitamin Studies

#1. Study using synthetic beta carotene and Vitamin E halted.

29,000 male smokers were given synthetic beta carotene and synthetic Vitamin E. The study was stopped when rates of lung cancer, heart attacks and death increased. – New England Journal of Medicine, 1994.

#2. Birth defects increased for women on synthetic supplements.

22,000 pregnant women were given synthetic Vitamin A. The study was halted because birth defects increased 400%. – New England Journal of Medicine, 1995.

new study in journal of medical association says synthetic vitamins increase risk of death
New Study in Journal of Medical Association Says Synthetic Vitamins Increase Risk of Death

A meta-analysis of 47 clinical trials found that the supplementation of synthetic forms of vitamin A, beta carotene, and vitamin E, at doses larger than commonly found in a balanced diet, actually increased mortality risk.

Researchers pointed out that their observations do not apply to natural antioxidants [vitamins] such as those found in fruits and vegetables.

JAMA

February 28, 2007

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Mineral Facts:

“Minerals are generally recovered by mining ores or from byproducts of chemical processes. Tests have shown that the minerals contained in the most popular brands of multivitamins do not dissolve (they are not soluble) in either the stomach or small intestine. They probably pass through the body without being absorbed.”

Minerals and Diet, Burt D. Ensley, PhD

slide27

Plant-Sourced Minerals

Plants uptake minerals through their root systems, predigest them and then bond them into a food matrix. This provides for increased solubility.

slide28

Real Food Technology® Solutions

Patented hydroponic growing techniques and new whole-food stabilizing processes provide for standardized, food-based nutrients.

the real food technology solution for vitamin mineral and phytonutrient supplementation
The Real Food Technology®Solution for Vitamin/Mineral and PhytoNutrient Supplementation

Technology Patent Filed 2007

slide31

Scientific Discovery

1990

The first Journal of Glycobiologywas published. In less than 10 years, the science of glycobiology had exploded to become one of the “hottest” new fields of medical and nutritional research.

slide32
Of the 200 sugars in nature, our cells use these eight like letters of an alphabet to make cellular words call glycoproteins.

Glyconutrients

*Glucose Xylose

Fucose N-acetylglucosamine

Mannose N-acetylgalactosamine

*Galactose N-acetylneuraminic acid

*Only two are commonly found in our diet

Harper’s Biochemistry Vol. 24. 1996

slide33

Sweet Language of Life

“Cell surface sugar [structures] are necessary for proper recognition and immune function.”

Nature, Vol. 373. Feb 16, 1995

slide34

Immune cells read the cell surface sugar structures on other cells to determine if they’re healthy, need repair or need to be destroyed.

missing sugars spell trouble
Missing Sugars Spell Trouble

When cells turn against the body, as in degenerative type functions, research has shown that sugars are missing from their glycoprotein structures.

“Removing a sugar [from its cell surface structures] turns protective antibodies (repair cells) into attackers.”

Capitalizing on Carbohydrates, 1991

Rockefeller University, July 4, 2007

slide36
Glycocompound Symposium:

In 1998, executives from 22 companies met to discuss how to develop drug-based glycocompound therapeutics.

Archer Daniels Midland Merck

Bayer AG MIT

Dow Chemical Monsanto Life Sciences

Dupont Proctor & Gamble

Genentech Stanford University

Medicine’s Last Frontier

Sweet Medicine:

Building Better Drugs from Sugars

(Synthesized Sugar Structures)

Scientific American, July, 2002

new theory
New Theory

Altered glycoprotein structures might be a result of dietary deficiency of vital sugars.

Father of Nutritional Glycobiology

ambrotose glyconutrient complex
Ambrotose®Glyconutrient Complex
  • The first standardized blend of plant-sourced polysaccharides.
  • 45 patents obtained worldwide for technology related to the Ambrotose® complex formulation.
slide39

“The notion that any saccharide mixture will improve health is flawed…”

“It’s none of our business as glycobiologists if nutraceutical companies want to sell bark extracts. When they begin to tie it to our discipline, that is a problem.”

Science,

2 November 2007, Vol. 318

slide40

Study Results:

  • For first time science has shown that the ingestion of a standardized blend of plant polysaccharides [Ambrotose] can induce significant changes in cell surface glycoprotein structures.
  • No adverse events.

An open-label dosing study to evaluate the safety and effects of dietary plant-derived polysaccharide supplement on the N-glycosylation status of serum glycoproteins in healthy subjects

3 tap into the passion that the public feels for your cause
#3 Tap into the Passion that the Public Feels for Your Cause

It Takes an Army of Concerned and Compassionate Individuals to Make a Global Impact

slide42

Mannatech’s

Donation Through Consumption Program

slide43

The model works best when

  • The product is the social vehicle that triggers social change;
  • The product is a response to market demand;
  • The business cannot be separated from the social mission. (Tom’s Shoes donates a pair for every pair sold.)

May 2011

4 f ind new ways to fairly compensate those who are willing to participate
#4Find New Ways to Fairly Compensate Those Who are Willing to Participate

Direct Marketing Model of Distribution and Compensation

slide45

Five million children under the age of five die each year from malnutrition.

  • 500 million people in world take a vitamin/mineral supplement.
  • GOAL: Educate and inspire 1% of them to switch from synthetically sourced to real food sourced vitamin/mineral.
how you can help
How You Can Help
  • Choose to become a consumer of products based on Real Food Technology® solutions.
  • Choose to take advantage of our Referral Rewards Plan.
  • Choose to become part of our Social Entrepreneurial movement that will change the world.
slide47

“Social Entrepreneurship is not about a few extraordinary people saving the day for everyone else. At its deepest level, it is about revealing possibilities that are currently unseen and releasing the capacity within each person to reshape a part of the world. It does not require an elite education; it requires a back-pack.”