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Drug eruption (Dermatitis medicamentosa)

Drug eruption (Dermatitis medicamentosa). 一 .Definition 二 .Etiologic Factors (Etiology) （一） The individual factors （二） Drugs. （二） Drugs Antibiotics 2. Antipyretic-analgesic drugs 3. Sedative-hypnotic drugs and Antiepileptic drugs 4 .Antigout (allopurinol)

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Drug eruption (Dermatitis medicamentosa)

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  1. Drug eruption (Dermatitis medicamentosa)

  2. 一.Definition 二.Etiologic Factors (Etiology) （一）The individual factors （二）Drugs

  3. （二）Drugs • Antibiotics • 2. Antipyretic-analgesic drugs • 3. Sedative-hypnotic drugs and Antiepileptic drugs • 4 .Antigout (allopurinol) • 5.Heterologous(Foreign) serum and Vaccine etc. • 6. Traditional chinese medicine

  4. 三.Pathogenesis: （一） Allergic （二） Nonallergic

  5. 四.Clinical Findings: （一）Fixed drug eruption： Antipyretic-analgesic drugs Sulfonamides Barbiturates

  6. （二）Urticarial drug eruption： Heterologous(Foreign) serum、 Furazolidone、Penicillin

  7. （三）Morbilliform drug eruption and Scarlatiniform drug eruption： Penicillin Sulfonamides Antipyretic-analgesic drugs Barbiturates

  8. （四）Eczematous drug eruption： Penicillin Streptomycin Sulfonamides Quinine

  9. （五）Purpuric drug eruption： Antibiotics Barbiturates Diuretics

  10. （六）Erythema multiforme drug eruption： Sulfonamides Antipyretic-analgesic drugs Barbiturates

  11. （七）Drug-induced bullosa epidermolysis： Sulfonamides Antipyretic-analgesic drugs Antibiotics Barbiturates

  12. （八）Drug-induced exfoliative dermatitis： Sulfonamides Barbiturates Antiepileptic drugs Antipyretic-analgesic drugs Antibiotics

  13. （九）Acneiform drug eruption： Glucocorticoid

  14. （十）Photosensitive drug eruption： 1. Phototoxic drug eruption 2. Photoallergic drup eruption

  15. 五.Diagnosis and Differential Diagnosis 六.Laboratory examination

  16. 七.Treatment 1、Antihistamine、VitC、Prednisone(30~60mg/d)、 50% GS 20ml + 10%Calcii Gluconas 10ml I.V. Qd 5% GS 250ml + 10%Calcii Gluconas 20ml I.V.gtt. Qd Lot. Calamine、 0.25％ Cream Prednisone、 0.1％ Sol. Rivanole

  17. 5%~10% G.S. 500ml + Hydrocortisone 150mg~200mg I.V.gtt. B.i.d. • 5%~10% G.S. 500ml + Dexamethasone 5mg~10mg • I.V.gtt. B.i.d.

  18. 八.Prophylaxis

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