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1. 1 Abdomen & GI systemFINAL RT 91- Pathology
Spring 2010
2. 2 Regions & Quadrants of Abdomen
3. 3 Contents of Abdominal Cavity Digestive system
Stomach and Intestines
Hepatobiliary System
Liver, gallbladder, & pancreas
Urinary system
Kidneys, ureters and bladder
Circulatory system
spleen
4. 4 Gastrointestinal System Alimentary tract- serves to digest & absorb food
Consists of
Mouth
Pharynx
Esophagus
Stomach
SM & LG bowel
Rectum
5. 5 Small Bowel 21 FT long
Duodenum
Duodenal c-loop ends at ligament of Treitz
Jejunum
Connects to ileum
Ileum
Terminates at ileocecal junction
6. 6 Large Intestine 6 FT long
Extends from ileocecal junction
Ascending colon (hepatic flexure)
Transverse colon (splenic flexure)
Descending colon
Sigmoid
Rectum
Anus
7. 7 Congenital and Hereditary Anomalies
8. 8 Esophageal Atresia Looping of the feeding tube
2. Atypically short esophagus & terminates in blind pouch
2. Air in stomach
9. 9 Esophageal Atresia
Congenital anomaly
Esophagus fails to _______________ past some point
Symptoms come soon after birth
Salivation, gagging, choking, dyspnea, cyanosis
10. 10 Tracheoesophageal Fistula
11. 11 Tracheoesophageal Fistula
12. 12 Duodenal Atresia
13. 13 Duodenal Atresia Congenital anomaly
________________ of duodenum does not exist
Resulting in a complete _________________
14. 14 Colonic Atresia
15. 15 Colonic Atresia Congenital failure of development of the ________________
Frequent complication includes fistula formation to the genitourinary system
Must be repaired surgically
16. 16 Hypertrophic Pyloric Stenosis
17. 17 Hypertrophic Pyloric Stenosis
18. 18 Hypertrophic Pyloric Stenosis
19. 19 Hypertrophic Pyloric Stenosis Congenital anomaly of the stomach
Pyloric canal leading out of the stomach is greatly narrowed because of hypertrophy of the pyloric sphincter
Most common indication for surgery in infants
20. 20 Malrotation Small bowel on
right and colon
on left
Cecum is not
located in the
RLQ
21. 21 Malrotation Intestines are not in their normal position
Usually asymptomatic
Can lead to bowel volvulus or incarceration of bowel
Surgery is required with a resection of bowel involved
22. 22 Hirschsprung's Disease ______________
Dilated ______ colon with massive amounts of feces
Narrowed segment just below the dilatation
23. 23 Hirschsprung’s DiseaseAKA Congenital Megacolon Absence of neurons in the bowel wall
This absence prevents normal relaxation of the colon & subsequent peristalsis
Results in gross dilatation
24. 24 Meckel’s Diverticulum
25. 25 Meckel’s Diverticulum Congenital ________________ of the distal ileum
Is remnant of a duct connecting the SB to the umbilicus in the fetus
26. 26 Celiac Sprue
27. 27 Celiac Sprue Hereditary disorder with increased sensitivity to gluten
Interferes with normal _____________ and _____________ of food
28. 28 Inflammatory Disease
29. 29 Esophageal Strictures
30. 30 Esophageal Strictures Caused by ingestion of caustic materials
Household cleaners
Detergents
Sulfuric acid
Sodium hydroxide
____ the esophagus causing edema, swelling, & possible perforation
Requires repeated _______________
31. 31 GERD Incompetent ______ sphincter allowing backward flow of gastric acid and food into esophagus
________________
________may not be evident with barium swallow but strictures & ulcers may be present
32. 32 GERD
33. 33 Peptic Ulcer Erosion of the mucous membrane of the esophagus, stomach & duodenum
Primarily affects PT’s over 40 years
Diagnosis is made mostly with endoscopy
34. 34 Peptic Ulcer
35. 35 Barrett’s Esophagus Peptic ulcer of the esophagus often with a stricture
Fibrotic healing of the ulceration
36. 36 Barrett’s Esophagus
37. 37 Crohn’s Disease
38. 38 Regional Enteritis (Crohn’s Disease) Chronic inflammatory disease of no cause
Typically occurs in lower ileum but can be seen throughout bowel
39. 39 Appendicitis
40. 40 Fecolith within Appendix
41. 41 Appendicitis Inflammation of the appendix resulting from an __________
Caused by a fecolith or neoplasm (rarely)
Most common abdominal surgery in the US
Sonography & CT used in diagnosis
42. 42 Ulcerative Colitis BE demonstrates an
irregular outline of the
colon
_______ _________ appearance
43. 43 Ulcerative Colitis Inflammatory lesion of the colon mucosa
Causes abscess leading to epithelial necrosis & ulceration
It is idiopathic, thought to be an autoimmune disease
44. 44 Esophageal Varices
45. 45 Esophageal Varices Varicose veins that are abnormally lengthened, dilated& superficial
Can be fatal
Occurs from conditions such
as cirrhosis that bypass the
normal venous drainage
mechanism
46. 46 Gastritis Evidenced by gas
bubbles (produced by
bacteria) in the stomach
Wall
47. 47 Endoscopy for Gastritis
48. 48 Gastritis 1. Inflammation of the
_______ of the stomach
2. Results from various
irritants: alcohol,
corrosive agents, &
infection
3. Most commonly
demonstrated with
___________________
49. 49 Degenerative Diseases
50. 50 Inguinal Herniation
51. 51 Inguinal Herniation Protrusion of a loop of bowel through a small opening, usually in the abdominal wall.
Can cause obstruction
Can be surgically repaired, sometimes needing resection
52. 52 Hiatal Hernia
53. 53 Hiatal Hernia Weakness of esophageal hiatus that permits some portions of the stomach to herniate into the thoracic cavity
Chronic herniation can be associated w/ ______
54. 54 Schatzki’s Ring A type of hiatal hernia
Occurs when a portion of the stomach and the gastroesophageal junction are both above the diaphragm (99%)
This ring is visible radiographically with this condition
May be related to reflux
55. 55 Bowel Obstructions
56. 56 Mechanical Bowel Obstruction
57. 57 Mechanical Bowel Obstruction Occurs from a blockage of the bowel lumen
Bowel sounds are _______________ & high pitched
Vomiting _________
58. 58 Gallstone Ileus
59. 59 Gallstone Ileus A type of mechanical obstruction
Gallstone can erode & create a fistula in the SB
Obstruction occurs when stone reaches ileocecal valve
60. 60 Paralytic Ileus Gas distributed
throughout both LG &
SB
Normal bowel sounds
are absent
61. 61 Paralytic Ileus Results from failure of peristalsis
Absent bowel sounds
62. 62 Volvulus
63. 63 Volvulus
Twisting of bowel loop
Usually at the sigmoid or ileocecal junction
Identifiable with x-ray
Usually happens in elderly
64. 64 Intussusception
65. 65 Intussusception Is a kind of mechanical obstruction
Segment of bowel telescopes into distal segment and is driven further into distal bowel by peristalsis
66. 66 Neurogenic Diseases
67. 67 Achalasia
68. 68 Achalasia Failure of the
esophageal sphincter to
relax causing dysphasia
Distal esophagus open
intermittently
69. 69 Diverticular Diseases
70. 70 Esophageal Diverticula Occurs when mucosal outpouchings penetrate through the muscular layer of the esophagus
71. 71 Esophageal Diverticula (traction)
Involves all layers of esophagus and results in adjacent scar tissue that pulls esophagus toward area of involvement
72. 72 Zenker’s Diverticulum
73. 73 Zenker’s Diverticulum Involves mucosa only & results from a __________ disorder
Allows esophagus to _________ outwardly
Found at pharyngealesophageal junction
74. 74 Colonic Diverticula
75. 75 Colonic Diverticula
76. 76 Colonic Diverticula The presence of diverticula _________inflammation
Diverticula are associated with hypertrophy of the muscular layer of the bowel
Most common in _____________ (95%)
Most patients are asymptomatic
77. 77 Diverticulitis Inflammation of the diverticulum
Exacerbated by feces lodging in the diverticulum
Signs and symptoms: fever, LLQ pain, tenderness and increased WBC count
BA shows diverticulum
Treatment centers on reduction of inflammation and infection
78. 78 Neoplastic Diseases
79. 79 Leimyomas
80. 80 Leimyomas of Esophagus __________ tumors
Have smooth muscular tumors
Exact location can be determined on CT
81. 81 GastroesophagealAdenocarcinomas
82. 82 Adenocarcinomas Occur in the lower esophagus around the gastroesophageal junction
Some believe there is a direct link between Barrett’s esophagus & adenocarcinoma
90% have been found to arise from Barrett’s mucosa
83. 83 Small Bowel Neoplasms
84. 84 Small Bowel Neoplasms Most occur in the duodenum & proximal jejunum
Some predisposing factors include:
Polyposis
Kaposi’s sarcoma
Crohn’s disease
85. 85 Colonic Polyps
86. 86 Colonic Polyps Small masses of tissue arising from the bowel wall to project inward in the lumen
More frequently in the left colon
Most cancers of the colon & rectum usually arise from previous benign polyps
87. 87 Colon Cancer 2nd most common cause of cancer mortality
Adenocarcinoma is the most common type of colorectal cancer
88. 88 Colon Cancer
89. 89 Colon Cancer“Apple-Core lesion” X-ray shows “napkin ring” or “apple core” lesions
Double contrast BE more accurate than single contrast
CT colonoscopy also useful
90. 90 CT of Abdomen & GI Clearly demonstrates abdominal organs that are normally not apparent on x-ray w/o contrast
Recommended for bowel obstruction diagnosis
Virtual colonoscopy can be done to see areas not seen during a regular colonoscopy
91. 91 MRI imaging of Abdomen & GI Still limited due to bowel motion
Useful in demonstrating retroperitoneal masses impinging on GI system
Can differentiate between pathology & normal tissue
92. 92 US imaging of Abdomen & GI Not useful in imaging of the GI system
Extensively used to image the retroperitoneum because of the flexibility of angling the transducer
With this modality it is possible to image behind the bowel & assess for abnormalities
93. 93 Nuclear Medicine imaging for Abdomen & GI Useful is detecting:
GI bleeds
Gastric emptying time
Presence of H. Pylori
Infection from gastric ulcers
PET has been known to demonstrate 20% of esophageal cancer undetected by CT
94. 94 Endoscopic Procedures Fiberoptic tube device to look inside hollow organs or cavities
Upper endoscopy can see esophagus, stomach, duodenum & proximal jejunum
Colonoscopy to the terminal ileum
Small bowel is still out of reach
Capsule endoscopy is a camera pill that is swallowed and takes pictures of the GI tract
Drawbacks include inability to biopsy area and locate pathology
Insurance reimbursement
Also used for several therapeutic applications
Biopsies
Stent placement
Polyp removal
Stone removal