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This study analyzes the impact of renal denervation on patients with treatment-resistant hypertension, highlighting significant reductions in office systolic blood pressure (SBP) by ≥10 mm Hg and ambulatory blood pressure (ABP) by ≥5 mm Hg. In this cohort, responder rates were observed at 80%, with efficacy measured at 3, 6, and 12 months. The findings emphasize the potential of renal denervation as a viable intervention for managing difficult-to-treat hypertension, providing insights into long-term treatment outcomes.
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100 Reduction of office SBP ≥ 10 mm Hg Reduction of ABP ≥ 5 mm Hg 80 Rates of responders to renaldenervation in patientswithtruetreatment-resistanthypertension 60 76,7 73,3 71,3 70 Proportion (%) 65 58,3 40 20 0 3 months 6 months 12 months Mahfoudet al. Circulation 2013