terry f hayamizu mouse genome informatics the jackson laboratory n.
Download
Skip this Video
Loading SlideShow in 5 Seconds..
Mouse Anatomy Ontologies and GXD PowerPoint Presentation
Download Presentation
Mouse Anatomy Ontologies and GXD

Loading in 2 Seconds...

play fullscreen
1 / 17

Mouse Anatomy Ontologies and GXD - PowerPoint PPT Presentation


  • 106 Views
  • Uploaded on

Terry F. Hayamizu Mouse Genome Informatics, The Jackson Laboratory . Mouse Anatomy Ontologies and GXD. Gene Expression Database (GXD) . Currently, GXD includes:

loader
I am the owner, or an agent authorized to act on behalf of the owner, of the copyrighted work described.
capcha
Download Presentation

PowerPoint Slideshow about 'Mouse Anatomy Ontologies and GXD' - gauri


Download Now An Image/Link below is provided (as is) to download presentation

Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author.While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server.


- - - - - - - - - - - - - - - - - - - - - - - - - - E N D - - - - - - - - - - - - - - - - - - - - - - - - - -
Presentation Transcript
terry f hayamizu mouse genome informatics the jackson laboratory
Terry F. Hayamizu

Mouse Genome Informatics, The Jackson Laboratory

Mouse Anatomy Ontologies and GXD

slide3

Currently, GXD includes:

  • a comprehensive literature index for mouse gene expression, with a primary emphasis on endogenous expression during embryonic development, covering >14,000 genes studied in >18,500 primary references
  • detailed experimental data for >12,700 mouse genes in >50,000 expression assays from ~5000 references, including data for >1,500 mouse mutants, as well as >200,000 images associated with expression data
  • over 1 million gene expression results annotated to specific mouse anatomy terms
slide5

stage-dependent DAGs

stage-independent

DAG

Stage i

s

S

t

u

v

T

U

V

x

w

X

Y

Stage j

W

s

EMAPA

u

v

x

y

EMAP

anatomy ontology for the postnatal mouse
anatomy ontology for the postnatal mouse

anatomy ontology for mouse development

developed by EMAP

developed by GXD

slide8

Represent develops-from relationships

TS X

“develops-from” relationships

TS Y

EMAP /

EMAPA

TS 28

MA

gene expression
GENE EXPRESSION

GENOTYPE

PHENOTYPE

DISEASE MODELS

GENETICS

slide11

Gene Expression

Phenotype

Anatomy

Disease

Biological Process

Pathological Process

slide12

Mammalian Phenotype ontology

Gene Expression Database

Adult Mouse Anatomy

NCI Thesaurus

Gene Ontology

Pathbase

slide13

Gene Expression

Gene Expression

Phenotype

Phenotype

Biological Process

Anatomy

Anatomy

Disease

Biological Process

Pathological Process

Disease

Pathological Process

Gene Expression

Phenotype

Biological Process

Anatomy

Pathological Process

Disease

slide17
Other Mouse Genome Informatics (MGI) resources

Mammalian Phenotype Ontology (MP)

Gene Ontology (GO)

Cell Ontology (CO)

Edinburgh Mouse Atlas Project (EMAP)

Duncan Davidson

Richard Baldock

Jonathan Bard

Matthew Kaufman

Gene Expression Database (GXD)

Martin Ringwald

Janan Eppig

Jim Kadin

Joel Richardson

Jacqueline Finger

Ingeborg McCright

Constance Smith

Jingxia Xu

Acknowledgements

GXD is funded by NIH/NICHD grant HD033745