NEONATAL ABSTINENCE SYNDROME DUE TO DEPENDENCY-INDUCING DRUGS. OUR EXPERIENCE WITH METHADONE TREATMENT. . V.Sideri , C.Vliora , A.Daskalaki , P.Mexi-Bourna , K.Kleanthous , M.Soulioti , G. Kyrkou , N.Bournas , V.Papaevangelou
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V.Sideri, C.Vliora, A.Daskalaki, P.Mexi-Bourna, K.Kleanthous, M.Soulioti, G. Kyrkou, N.Bournas, V.Papaevangelou
3rd Pediatric Clinic of the University of Athens,
"Attikon" Hospital, Athens Greece
Neonates born to mothers taking
are at an increased risk of developing Neonatal Abstinence Syndrome (NAS)
Our aim was to study methadone
substitution-treatment of NAS caused by
In addition, we used supportive nopharmacologic therapy (dark and quiet environment, slow and gentle handling of these infants, sometimes tight swaddling, small- frequent feedings, holding and rocking)
All of the aforementioned infants presented with NAS and were treated with oral methadone (except one, who was treated with phenobarbital).
There were no complications neither from NAS nor from the methadone administration (excepting the case in which phenobarbital was administered and who subsequently developed seizures on the 13th day of life)