Population Structure and Genetic Analysis

Feb 22, 2014

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Population Structure and Genetic Analysis

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Genetic and the human population

616 views • 39 slides

Population structure

Population structure. Population structure in case-control studies. Population consists of underlying subpopulations. Disease prevalence different between subpopulations. Cases preferentially ascertained from specific subpopulations.

396 views • 21 slides

Mutation can change population genetic structure

Mutation can change population genetic structure. Mutation rates are low typically <1/10,000 per generation ( μ ≤ 0.0001) Loss-of-function mutations are much more common than back mutations that restore function. WHY?. How does selection cause change in allele frequencies?.

334 views • 10 slides

Population Genetic

Population Genetic. Hardy-Wienberg Law Genetic drift Inbreeding Genetic Bottleneck Outbreeding Founder event Effective population size Gene flow. Population Genetics. Genotype, phenotype locus, genotype frequency, allele frequency. Determining the genotype for an enzyme in a fish.

497 views • 10 slides

Population structure and control

Population structure and control. What is a census ? Why is it difficult to compare census information between countries ? Why can census information be unreliable ? How can population presented ? Name as many ways as you can. http://www.indexmundi.com/g/g.aspx?v=21&c=sp&l=en.

334 views • 6 slides

Population Structure

Population Structure. I. Population Characteristics. Population size = the number of individual organisms present at a given time Population density = the number of individuals in a population per unit area Varies by species: Large organisms=low density High isn’t always bad

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Population Genetic Structure and Race/Ethnicity

Population Genetic Structure and Race/Ethnicity. Outline. How is genetic variation structured in the human population? What is the relationship between population genetic variation and race/ethnicity? Racially (ancestrally) admixed populations: African Americans and Latino Americans

1.09k views • 78 slides

Population Theories Population structure and aging

Population Theories Population structure and aging. Age and sex composition Proportion of males and females in each age group. Age (and sex) composition strongly influences demographic patterns (births, deaths, migrations, marriages). Demographic behaviours influence

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POPULATION STRUCTURE

POPULATION STRUCTURE. 3. 2. 1. POPULATION STRUCTURE. A. A. B. B. POPULATION STRUCTURE. Gene flow (migration*). Low levels of gene flow (migration*). High levels of gene flow (migration*). POPULATION STRUCTURE. Natural selection.

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Population Genetic Structure and Race/Ethnicity

Population Genetic Structure and Race/Ethnicity. EPI 217 Molecular and Genetic Epidemiology Winter 2011. Outline. How is genetic variation structured in the human population? What is the relationship between population genetic variation and race/ethnicity?

680 views • 51 slides

Population Genetic Structure and Race/Ethnicity

Population Genetic Structure and Race/Ethnicity. EPI 217 Molecular and Genetic Epidemiology Winter 2012. Outline. How is genetic variation structured in the human population? What is the relationship between population genetic variation and race/ethnicity?

918 views • 77 slides

Non-random mating can change population genetic structure

Non-random mating can change population genetic structure. Non-random mating – does not change allele frequencies – does cause genotype frequencies to differ from p 2 , 2pq, q 2 Types of non-random mating Assortative mating – mates are genetically similar

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Mutation can change population genetic structure

337 views • 10 slides

Population Structure

Population Structure. Partitioning of Genetic Variation. Banner-tailed kangaroo rat ( Dipodomys spectabilis ). Distribution of populations. SSW. 1 km. R2. Distribution of populations. 1 km. Distribution of populations. 1 km. Distribution of populations. 1 km.

576 views • 34 slides

Population Structure and Genetic Diversity in South Tunisian Hedysarum

Population Structure and Genetic Diversity in South Tunisian Hedysarum. Mohamed Neji, Sondes Rahmouni, Malek Smida, Wael Taamalli, Mhemmed Gandour et Chedly Abdelly Corresponding author: Mhemmed Gandour ( gandourmed@yahoo.fr )

236 views • 1 slides

Population Genetic Structure and Race/Ethnicity

Population Genetic Structure and Race/Ethnicity. EPI 217 Molecular and Genetic Epidemiology Winter 2013. Outline. How is genetic variation structured in the human population? What is the relationship between population genetic variation and race/ethnicity?

966 views • 77 slides

Population Genetic Structure Analysis of The Emerging Marine Pathogen, Vibrio vulnificus

6th July, 2006. Population Genetic Structure Analysis of The Emerging Marine Pathogen, Vibrio vulnificus. Bisharat et al Analyses by RM Harding. Here is where we started: Why two clusters? How are they related to each other? What is their origin?.

430 views • 26 slides

Population Structure

Wednesday 15 th September 2011. Population Structure. Lesson Objective: To be able to construct and interpret population pyramids and understand their characteristics. Starter. LEDCs have high…? LEDCs have low…? MEDCs have low…? MEDCs have low…?. Demographic Transition model. (DTM).

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Why study population genetic structure?

Why study population genetic structure?. In general, provides perspective on adaptation and speciation. Can reveal the recent demographic history of a population and the role of: Gene flow Genetic drift Inbreeding Natural selection Population size

397 views • 12 slides

Genetic analysis of population

Genetic analysis of population. Definitions. Population: a group of interbreeding individuals Genotypic frequency: The frequency of a specific genotype in a given population (AA, Aa, aa) Allele frequency: The frequency of a specific allele within a given population

433 views • 38 slides

POPULATION STRUCTURE

POPULATION STRUCTURE. OBJECTIVES At the end of this lesson you should be able to…. Interpret population pyramids for MDCs and LDCs Calculate dependency ratios Discuss the implications of dependency ratios Examine case studies of countries exhibiting ageing and youthful populations.

291 views • 23 slides

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