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0 kbp. Cbl Biosynthesis Cluster 1. PFOR complex. cbiE. metE. Cbl Biosynthesis Gene cobA. cbiK. sirA/cysG. Inferred Gene Function. 15 kbp. Cobalamin biosynthesis. 60 kbp. Cobalamin- or ion-related transport. TonB-dep. receptor. Plasmid replication/stability.

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slide1

0 kbp

Cbl Biosynthesis Cluster 1

PFOR complex

cbiE

metE

Cbl Biosynthesis

Gene cobA

cbiK

sirA/cysG

Inferred Gene Function

15 kbp

Cobalamin biosynthesis

60 kbp

Cobalamin- or ion-related transport

TonB-dep.

receptor

Plasmid replication/stability

Additional metabolic functions

Tn3

transposase

cobN

oriR –

predicted origin of replication

TonB-dep.

receptor

hipB-hipA

cobD/cbiP

parA

repA

Cbl Biosyntesis

Cluster 2