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Update on “Disease Burden Attributable to Risk Factors in the US” Project

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  1. Update on “Disease Burden Attributable to Risk Factors in the US” Project Armineh Zohrabian, CDC IAWG on Summary and Outcome Measures of Health July 12, 2006

  2. Presentation Outline • Overview of the specific activities of CDC/Harvard University current Burden of Disease (BOD) project • Brief mention of CDC’s Health Related Quality of Life Surveillance Program

  3. BOD Project • CDC/Harvard University cooperative agreement • $325,000 over 3 years (2004-2007)

  4. BOD Objectives • Update 1996 disease burden estimates to the year for which most recent data are available (2001) • Estimate distributions and trends of total and risk-factor attributable disease burden by age, sex, race and geography

  5. Specific Activities Inputs for estimating disease burden attributable to risk factors are: • Risk factor exposure • Uses risk assessment module from the Comparative Risk Assessment (CRA) Project, WHO • Risk factor hazard • Estimates will be based on systematic review of epi literature • Burden of disease • Will use Disability Adjusted Life Years (DALYs)

  6. Specific Activities (continued) • Collation of data sources and development of methods to • re-distribute ill-defined causes of death in the US (completed) • estimate unbiased overweight and obesity trends from self-reported data (completed) • estimate unbiased trends for other risk factors from self-reported data (initiated) • estimate sub-national risk factor exposure and trends in risk factor exposure (ongoing) • Development of new algorithms to update 1996 US burden of disease estimates to the year 2000 or 2001(ongoing)

  7. Contribution to scientific literature • Ezzati M, Martin H, Skjold S,Vander Hoorn S, Murray CJ. Trends in National and State-Level Obesity in the USA after correction for self-reported bias. JR Soc Med. 2006 May; 99(5):250-7. Erratum in: J R Soc Med. 2006 Jun;99(6):280. • Christopher J.L. Murray, Sandeep C. Kulkarni and Majid Ezzati. Understanding the Coronary Heart Disease Versus Total Cardiovascular Mortality Paradox: A Method to Enhance the Comparability of Cardiovascular Death Statistics in the United States.Circulation 2006;113;2071-2081

  8. CDC's Health-Related Quality of Life Surveillance Program • Housed in the Division of Adult and Community Health, National Center for Chronic Disease Prevention and Health Promotion   • Its purpose is to learn about unmet health needs; recognize trends, disparities, and determinants of health in the population • It uses the Healthy Days surveillance measures in summary measures of population health

  9. Resources on Healthy Days Measures • Moriarty DG, Zack MM, Kobau R, Zahran HS. Tracking Health-Related Quality of Life in the United States 1993-2004. Presented at the Institute of Medicine Committee to Evaluate Measures of Health Benefits for Environmental, Health, and Safety Regulation. Washington, DC, December 1, 2004.  See PowerPoint slides @ http://www.iom.edu/subpage.asp?id=23875 • Klementiev A. Chapter 5 -- An Alternative Measure of Years of Healthy Life, from:Estes RJ (Ed). Social Indicators Research Series, 2006; 29 ISBN: 1-4020-5099-2 [In press, available November 15, 2006].     • For additional information, including copies of the measures,  annual state-based HRQOL prevalence data from 1993 and later, and references to research based on the measures, please see the CDC HRQOL Website at http://www.cdc.gov/hrqol .

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