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Cochlear model’s geometry

עבוד אותות במערכת החושים סמסטר א' תש"ע http://www.eng.tau.ac.il/~mira/Senses2009 Virtual Lecture 4. Cochlear model’s geometry. The Cochlear Model Equations: I. Linear Approximation II. OHC are not Active. Frequency Domain Solution. Resonance Frequency.

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Cochlear model’s geometry

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  1. עבוד אותות במערכת החושיםסמסטר א' תש"עhttp://www.eng.tau.ac.il/~mira/Senses2009VirtualLecture 4

  2. Cochlear model’s geometry

  3. The Cochlear Model Equations:I. Linear ApproximationII. OHC are not Active

  4. Frequency Domain Solution

  5. Resonance Frequency Resonance Frequency is obtained at the frequency that yields: Resonance Frequency= Characteristic Frequency

  6. OHC Anatomy

  7. OHC’s model

  8. OHC model’s equation

  9. Known Facts & Assumptions • The outer hair cell motility is proportional to the basolateral membrane voltage drop. • The membrane electric analog is a low-pass filter with a cutoff frequency less than 1 kHz. • The capacitance changes with the partition motion. • The current flow through the basolateral membrane is a function of the partition displacement and velocity.

  10. Assumptions

  11. OHC Properties: Linear Approximation

  12. OHC Force γ(x) - is the relative population of OHCs per unit length

  13. OHC Pressure Equation - Substituting the linear approximations in the OHC electrical potential equation yields:

  14. The Embedded Cochlear Model

  15. Parameters Estimation For and

  16. Frequency Domain Equations

  17. WKB Approximation • A1 and A2 are determined by the boundary condition

  18. Model’s Simulation

  19. Cochlear representationsof Chirp Cochlear representation

  20. Cochlear representationsof “SHEN” Cochlear representation

  21. Impaired Hearing

  22. Audiograms CONDUCTIVE HEARING LOSS Sensorineural Hearing Loss

  23. Simulated Audiograms Estimated Loudness: - For Input Signal: Estimated Hearing Level is defined as:

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