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Infection Control in the Dialysis Setting Part 3 of 4. Danilo B. Concepcion CCHT, CHT Manager, Renal Technology Services. Email: danilo.concepcion@stjoe.org Phone: 714.771.8944. The findings and conclusions in this presentation are those of the author
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Infection Control in the Dialysis Setting Part 3 of 4 Danilo B. Concepcion CCHT, CHT Manager, Renal Technology Services Email: danilo.concepcion@stjoe.org Phone: 714.771.8944 The findings and conclusions in this presentation are those of the author and do not necessarily represent the views of St. Joseph Hospital
The Problem of Infection • Second leading cause of death (after CVD) • Vascular access is the leading cause of hospitalization • Bacteremia (ranging from 7000 to 15,000 cases per year) can result in: • Septic shock • endocarditis • Septic arthritis • Osteomyelitis • Epidural abcesses • Exposes patients to multiple antibiotics and at risk for antibiotic resistance Allon (2004)
Epidemiology of Infections Among Hemodialysis Patients • Site of infection • 57% vascular access • 23% wound • 15% lung • 5% urinary tract USRDS 2005 Annual Data Report Tokars, Miller, Stein. AJIC 2002;30:288-295
The Problem of MRSA Infection • Overall incidence of infection is 45.2 cases per 1000 patients – 100 times that of the general population (0.2 – 0.4 per 1000) • MRSA poses the biggest threat to dialysis patients (HD & PD) • 74% of the cases were in dialysis patients > 50 years old • 85% of the dialysis patients had catheters or other invasive devices in place • 90% of dialysis cases were hospitalized • 17% MRSA cases resulted in death
Differences in Event Rates: Fistula vs. Catheter Tokars, Miller, Stein. AJIC 2002;30:288-295 Pastan, Soucie, McClellan. Kidney Int 2002;62:620-626
Rate of Hospitalization by Vascular Access Type Dialysis Surveillance Network 1999-2005
Rate of Vascular Access Infection by Vascular Access Type Dialysis Surveillance Network 1999-2005
Rate of Access-Related Bloodstream Infection by Vascular Access Type Dialysis Surveillance Network 1999-2005
Types of Vascular Access, U.S. Hemodialysis Patients, by Year Finelli, Miller, Tokars. Semin Dial 2005;18:52-61