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Explore the growing threat of antibiotic resistance with insights from research articles and data on MRSA cases in Europe. Learn about the impact of resistance on healthcare fatalities and the urgency for effective drug development.
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Increased knowledge on an increasing problemnumber of hits in Pub-MED for (antibiotic or antimicrobial) + resistance by 5 year’s periods
The tip of the iceberg… • Crude estimate from Israel: 4% of all fatalities in hospitals related to Gram-neg multiresistant nosocomial inf. (Carmeli 2005) • Crude estimate from EU-15: 5,800 excess deaths in ICU related to resistance (Harbarth et al 2005) • Rough estimate of global gonnorhoea treatment failure:3 million cases annually (of total 62 million cases) (Tapsall 2005)
The Current Paradox Antibiotic Resistance Drug Development
Sales of Antibiotics in the Nordic Countries1978-2004 DDD/1000 inhabitants/day
Sveriges beredskap är god? Optimal sjukhusanvändning? Optimal kinolonanvändning? Optimal diagnostik? Optimal hygien? Optimal profylax?
Guidelines does not work unless they are implemented ! Implementation does not work unless there is local comittment and educational outreach !