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Discover the success of Gregor Mendel, the Father of Genetics, through his innovative research on pea plants. Explore his pre-Mendelian ideas on inheritance, blending, and homunculus. Find out why Mendel’s choice of research organism, the pea plant, was crucial for his breakthroughs. Uncover Mendel's key experiments, conclusions, and the principles of dominance, segregation, and independent assortment. Learn about the extensions to Mendel's work, including incomplete dominance, co-dominance, and polygenetic inheritance. Dive into the fascinating world of genetics with Mendel's revolutionary discoveries.
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Fr. Gregor Mendel Father of Genetics1822 - 1884
Pre-Mendelian Ideas on Inheritance • Blending • Homunculus
Why was Mendel Successful? • Good Research Organism (pea plant) * Small, easy to grow in large numbers * short life cycle could test several generations * Could cross or self-pollinate
Why was Mendel Successful? • Good Research Organism (pea plant) * Small, easy to grow in large numbers * short life cycle could test several generations * Could cross or self-pollinate * Were “politically correct” (Explain!)
Why was Mendel Successful? • Good Research Organism (pea plant) • Had good math/statistical background • Picked good pairs of traits to study:ex: Tall/shortex: (find for HW!)
Mendel’s Experiments Experiment #1 • Created “pure breeding” tall plants • Created “pure breeding” short plants
Experiment #1 (cont)Crossed two F1 plants (Monohybrid Cross!)
Same pattern • w “pure-breeding” purple & white:
Mendel’s Conclusions • Organisms inherit two “factors” for each trait, one from each parent • Principle/Law of Dominance • Principle/Law of Segregation • Law of Independent Assortment(Based on next cross…)
Pure Purple Tall x Pure Short White P : F1 F2: (Homework):
Test Cross: Learn, then explain what it is & why Prof Dillon hates the following diagram:
Extensions to Mendel • Incomplete dominance • Co-dominance • Pleiotrophy • Polygenetic inheritance
Incomplete Dominance In snapdragons,R red petals r white petals
Incomplete Dominance If you mate a red with a white snapdragon… • RR X rr
Incomplete Dominance If you mate a red with a white snapdragon… • RR X rr R r
Incomplete Dominance If you mate a red with a white snapdragon… • RR X rr r R r R
Co-dominance I A type A markers on surface of RBC I B type B markers on surface of RBC i neither A nor B markers on surface of rbc
Polygenetic Each allele melanin deposition The more genes, the more pigment (melanin).
Remember:Environment influences Phenotype Same genotype!!