Clinical Pharmacology of A nti-inflammatory Agents. RHEUMATIC DISEASES. Rheumatic diseases (rheumatism) are painful conditions that affect millions. These diseases cause inflammation, swelling, and pain in the joints or muscles.
Venus Williams Diagnosed With Sjogren’s Syndrome
Propionic acid derivatives
Acetic acid derivatives
Enolic acid (Oxicam) derivatives
Fenamic acid derivatives
( Fenamates )
Selective COX-2 inhibitors (Coxibs)
The more an NSAID blocks COX-1, the greater is its tendency to cause ulcers and promote bleeding. Butcelecoxib (Celebrex), blocks COX-2 and has little effect on COX-1, and is therefore further classified as a selective COX-2 inhibitor. Selective COX-2 inhibitors cause less bleeding and fewer ulcers than other NSAIDs.