Accolade qs alexandrite 755 nm benign pigmented lesions and tattoo removal
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Accolade QS Alexandrite 755 nm Benign Pigmented Lesions and Tattoo Removal. Market Size and Incidence. Epidermal Lesions- Superficial 30% of population has solar lentigines 10% of population has café-aulait 60% have freckles Dermal Lesions

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Accolade qs alexandrite 755 nm benign pigmented lesions and tattoo removal

Accolade

QS Alexandrite 755 nm

Benign Pigmented Lesions and Tattoo Removal


Market Size and Incidence

  • Epidermal Lesions- Superficial

    • 30% of population has solar lentigines

    • 10% of population has café-aulait

    • 60% have freckles

  • Dermal Lesions

    • Nevus of Ota and Ito (Acquired Dermal Melanocytosis)

      • 0.014%-0.034% of Asian population

      • 0.4-0.8% of people of Japanese and Korean descent

  • Cosmetic, Medical, Body Art Tattoo

    • Permanent makeup tattoos

    • Reconstructive medical tattoos after mastectomy and surgery

    • Cosmetic tattoos to cover up scars and other skin imperfections

    • Body Art Tattoos


Treatment market size
Treatment Market Size

  • Benign Pigmented Lesion Removal

    • Global treatment size $2.50 Billion to $6.48 Billion

    • 2008 expected US market size $38 M at CAGR 12%*

  • Tattoo Removal

    • 2008 expected US market size $120 M at CAGR 17%*

    • International market estimated $45 M

*Source: Millennium Research Group


Nanosecond

Pulse Width

Equal amounts of energy

Power

Microsecond

Pulse Width

Nano vs microsecondPulse Width

  • Effectively destroys melanosomes and tattoo pigments

  • Ultra-short pulse widths required to shatter melanosome/ pigments by photoacoustic effect

Courtesy of:

Dr. Wang Hongwei

Peking Union Medical College Hospital

Time


Benign pigmented lesions
Benign Pigmented Lesions

  • Discoloration caused by high concentration of melanocytes in a particular area

    • Treatments include cover up with makeup, or painful removal by dermabrasion or cryosurgery

    • Mostly for pediatric treatments or as an adjunct procedure in skin rejuvenation for adults

  • Lasers remove pigmented lesions through photoaccoustic effects

    • Melanin absorbs laser energy more intensely than the surrounding tissue which leads to fracturing of the pigment and melanocyte cell death

    • Fractured melanin/melanocyte is removed by the immune system


Nevus of ota
Nevus of Ota

  • First described in 1861

  • Bluish hyperpigmentation along the first or second branches of trigeminal nerve

  • Most patients have no family history

  • Age of onset- perinatal period or puberty

  • Significant predominance among women

    • Male to female ratio 1:4.8

  • Female hormones suggested as potent stimuli

  • Other stimuli include infection, trauma, or ultraviolet light exposure

Source: Chan and Kono et al Nevus of Ota: Clinical Aspects & Management, SKINmed, 2003


Nevus of ito mongolian spots other conditions
Nevus of Ito, Mongolian spots & Other conditions

Nevus of Ito

  • Variant of Nevus of Ota.

  • Skin pigmentation occurs is more diffuse and less mottled in the acromioclavicular region

    Mongolian spot

  • Sacrococcygeal region

  • Usually regresses and disappears during childhood.

  • The spot is found in almost all newborn Chinese, Japanese and Mongolian children, as well as some white and black children.

    Becker Nevus and Henry Nevus




Incidence – Tattoos

  • Sixth fastest-growing retail business in the United States in recent years

  • 80% of tattoo customers are upper middle-class white suburban females

  • 15-20% of US teens and young adults have tattoos (40M Americans)

  • 23% of college students have tattoos

  • 50% of everyone receiving a tattoo, wants it removed (ASDS)

    “In the 90’s I did five laser treatments a month… now I do that in one day” Elizabeth McBurney, MD

Source: The Pulse, Hofstra University and ASDS- American Society of Dermatologic Surgery




The accolade
The Accolade

  • Q-Switched Alexandrite Laser

    • The Speed of Alex

    • The Spot Size of Ruby

  • Removes Pigmented Lesions

  • Removes Black, Blue, Brown and Green Tattoos


Correct wavelength for specific treatment
Correct Wavelength for Specific Treatment

Alexandrite 755 nm


Effective wavelengths

1320nm Nd:YAG

Effective Wavelengths

Accolade

  • 755nm

    • Absorbed by most pigments

    • Greater depth of penetration for treating deeper structures

  • 50-70 ns pulse width

    • Disrupts melansomes and tattoo pigments



Accolade improved design
Accolade Improved Design

  • Faster than other competing systems

    • 2x spot size of other Alex

    • More than 10x the speed of Ruby

  • Faster Treatments and Faster Clearance

    • Larger Spot and Higher Repetition rate give the fastest treatment possible

    • Larger Spot means deeper penetration for faster clearance


Accolade treatments characteristics
Accolade Treatments Characteristics

  • Accolade treatments are gentler

  • Less painful especially for the face

  • Greater specificity towards target chromophore

  • Reduces damage to peripheral tissue

  • Minimum pinpoint bleeding

  • Decreases incidence of scarring


Accolade features and benefits
AccoladeFeatures and Benefits





Nevus of ota before after
Nevus of Ota Before & After

BEFORE

AFTER

4 treatments

Courtesy of:

Dr. Wang Hongwei

Peking Union Medical College Hospital


Nevus of ota before after1
Nevus of Ota Before & After

BEFORE

AFTER

Courtesy of:

Dr. Wang Hongwei

Peking Union Medical College Hospital

7 treatments


Pigmented lesion before after
Pigmented Lesion Before & After

BEFORE

AFTER

3 treatments

Courtesy of:

Dr. Wang Hongwei

Peking Union Medical College Hospital


Freckles before after
Freckles Before & After

BEFORE

AFTER

1 treatment

Courtesy of:

Dr. Wang Hongwei

Peking Union Medical College Hospital


Tattoo Treatment Before & After

Eyebrow Tattoo

BEFORE

AFTER

After 2 treatments (5.8-8.6 J/cm2)

Courtesy of:

Dr. Lu Zhong Huashan Hospital

Caution: Spot test first. Tattoo pigments with iron may turn jet black with laser; continue treatment for black


Tattoo treatment before after
Tattoo Treatment Before & After

BEFORE

AFTER

After 3 treatments (5.8-8.6 J/cm2)

Courtesy of:

Dr. Lu Zhong Huashan Hospital


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