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MEWDS Multiple Evanescent White Dot Syndrome. General Hospital Pula Croatia Department of Opthtalmology Edi Ladavac. Clinical features. Strong female predominance Young adults One eye Blurred vision and fotopsia Average duration of 6 weaks Good recovery of visual function.

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mewds multiple evanescent white dot syndrome

MEWDSMultiple Evanescent White Dot Syndrome

General Hospital Pula Croatia

Department of Opthtalmology

Edi Ladavac

clinical features
Clinical features
  • Strong female predominance
  • Young adults
  • One eye
  • Blurred vision and fotopsia
  • Average duration of 6 weaks
  • Good recovery of visual function
clinical picture
Clinical picture
  • Multiple white dots at the level of the deep retina or RPE
  • Blurring of the disk margins
  • Granular orange or yelow dots in the macula
ancillary testing
Ancillary testing
  • FAG
  • ICG angiography
  • Visual field
  • ERG
fluorescein angiography
Fluorescein angiography
  • Early and late hyperfluorescence of the white dots
  • Diffuse (patchy) late staining at the level of RPE
  • Disk capillary leakege
case 1 fag
Case 1 - FAG

normal eye

MEWDS

case 2
Case 2

Visus : 0,6

case 2 fag
Case 2 - FAG

FAG 2

FAG 1

FAG 3

case 2 fag10
Case 2 - FAG

normal eye

MEWDS

visual field
Visual field

Enlarged blinde spot

icg angiography
ICG angiography

demonstrate a greater

number of lesions than are seen with ophthalmoscopy or FAG

Yannuzzi

differential diagnosis white dots syndroms
Differential diagnosiswhite dots syndroms
  • Multifocal choroiditis
  • APMPPE
  • Acute idiopathic blind spot enlargement sy
  • Punctate inner choroidopathy
  • Acute macular neuroretinopathy
  • Acute zonal occult outer retinopathy
conclusion
Conclusion

The disease usually has a self-limited course with good visual recovery. Approximately 90% of patients have better than 20/30 final visual acuity. There is a return of normal funduscopic appearance, although macular changes may persist.

Because of its self-limited course, no treatment for MEWDS currently is indicated.