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SUPERFICIAL FUNGAL INFECTION DERMATOPHYTOSIS

SUPERFICIAL FUNGAL INFECTION DERMATOPHYTOSIS. THREE GENERA KNOWN TO CAUSE DISEASE -TRICOPHYTON - MICROSPORUM - EPIDERMOPHYTON. EPIDEMIOLOGY.

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SUPERFICIAL FUNGAL INFECTION DERMATOPHYTOSIS

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  1. SUPERFICIAL FUNGAL INFECTION DERMATOPHYTOSIS THREE GENERA KNOWN TO CAUSE DISEASE -TRICOPHYTON - MICROSPORUM - EPIDERMOPHYTON

  2. EPIDEMIOLOGY • GEOPHILIC - – M.GYPSEUM – M. FERRUGINEUM - T. TERRESTRE - T.VIOLACEUM • ZOOPHILIC - - M. CANIS – CAT, DOGS,SHEEPS - T. EQUINUM – CATS, DOGS,CATTLES - T. VERRUCOSUM – CATS , DOGS, CATTLES,SHEEPS • ANTHROPOPHILIC - -E. FLOCCOSUM –M. AUDOUINII –T. MENTAGROPHYTES –T. RUBRUM – T. TONSURANS –

  3. PATHOGENESIS • FUNGI MUST OVER COME - EFFECT OF UV LIGHT –TEMPERATURE VARIATION – COMPITION WITH NORMAL FLORA -FUNGISTATIC AGENTS – • FATTY ACIDS,SPHINGOSINES • - EPIDERMAL GROWTH • DTH IMMUNE RESPONSE

  4. TINEA CAPITIS

  5. ORGANISMS ASSOCIATED WITH CLINICAL TYPES OF TINEA CAPITIS

  6. TINEA CAPITIS

  7. TINEA CAPITIS

  8. TINEA CAPITIS

  9. BLACK DOT TINEA CAPITIS

  10. INFLAMMATORY T. CAPITIS

  11. TINEA BARBAE • INFAMATORY TYPE- T. MENTAGROPHTE, T. VERRUCOSUM • SUPERFICIAL TYPE - ANTHROPOPHILIC –T. VIOLACEUM,T.RUBRUM • CIRCINATE TYPE

  12. TINEA BARBAE

  13. TINEA FACEII

  14. TINEA FACEII

  15. TINEA BARBE

  16. TYPICAL TINEA CORPORIS

  17. TINEA CORPORIS

  18. INFLAMMATORY T. CORPORIS

  19. TINEA CORPORIS

  20. TINEA CORPORIS

  21. TINEA CORPORIS

  22. TINEA CORPORIS

  23. TINEA UNGUIUM

  24. TINEA UNGUIUM

  25. TINEA UNGUIUM

  26. TINEA MANUM

  27. TINEA MANUM

  28. TINEA MANUM

  29. TINEA CRURIS

  30. TINEA CRURIS

  31. TINEA CRURIS

  32. TINEA CRURIS

  33. TINEA CRURIS

  34. TINEA PEDIS • CHRONIC INTERTRIGINOUS TYPE • CHRONIC HYPERKERATOTIC TYPE • VESICULOBULLOUS TYPE • ACUTE ULCERATIVE TYPE

  35. TINEA PEDIS

  36. TINEA PEDIS

  37. TINEA PEDIS

  38. TINEA PEDIS

  39. TINEA PEDIS

  40. KOH MOUNT

  41. ENDOTHRIX FUNGUS

  42. ECTOTHRIX FUNGUS100X

  43. TREATMENT SYSTEMIC THERAPY TOPICAL THREAPY **

  44. SYSTEMIC ANTIFUNGALS • ALLYLAMINS – • INHIBITS SQUALENE EPOXIDASE BLOCKING BIOSYNTHESIS OF ERGOSTEROL • FUNGICIDAL • 3 TO 6 mg/kg OD • CONTRAINDICATED IN PREGNANCY & LACTATION • TRIAZOLES – ITRACONAZOLE, FLUCONAZOLE INHIBIT 14 alfa DEMETHYLASE ENZYME IN CELL MEMBRANE USEFUL FOR CONVERSION OF SQUALENE TO ERGOSTEROL . IMIDAZOLE – KETOCONAZOLE GRISEOFULVIN – DISRUPS MICROTUBULE MITOTIC SPINDLE FORMATON THUS ARREST MITOTIC AT METAPHASE STAGE

  45. TREATMENT TOPICAL -ALLYLAMINES – TERBINAFINE,NAFTIFINE -BENZYLAMINE - BUTENAFINE -IMIDAZOLES CLOTRIMAZOLE, MICONAZOLE, KETOCONAZOLE -TOLNAFTAE

  46. THANK YOU….,

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