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Use preformed components to non-specifically clear the agent

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Use preformed components to non-specifically clear the agent

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    6. Cells and Tissues of the Immune System Lecture 2

    7. Cells of the Immune System Tissues/Organs of the Immune System

    8. Cells of the Immune System

    9. Hematopoiesis

    10. Lymphocytes

    12. B Cells T Cells NK Cells

    18. Mononuclear Phagocytes Monocytes and Macrophages Dendritic Cells

    19. Functions Phagocytosis Antigen processing and presentation (APCs) Activation of T cells

    20. Origin and Development of Macrophages

    22. Dendritic Cells Transport Antigens to L. nodes Initiation of T Cell Responses

    23. Dendritic Cell Subsets

    26. Lymphoid Organs

    27. Lymphoid Organs

    28. Lymphoid Organs Primary (Generative) Lymphoid Organs maturation site of lymphoid cells bone marrow, bursa of Fabricius, thymus, Peyer’s Patches in Pigs and Ruminants Secondary Lymphoid Organs efficient at trapping and concentrating foreign substances site of Ag-driven proliferation and differentiation; e.g. Ab production spleen, lymph nodes, diffuse tissues

    29. Primary Lymphoid Organs

    30. Thymus Site of T cell maturation. Relative Size Greatest in Newborn Absolute Size Greatest at Puberty

    33. Effect of Thymectomy in Adult

    34. Bone Marrow Site of hematopoiesis. Site of B cell maturation in mammals.

    35. Bursa of Fabricius Site of B cell maturation in birds.

    36. Peyer’s Patches Site of B Cell Maturation -Pigs and Ruminants

    37. Secondary Lymphoid Organs

    39. Lymph Nodes Local sites of specific immune response. Strategically placed on lymphatic channels.

    43. Spleen Site of immunological responses against blood-borne Ags. White pulp rich in lymphoid cells. Red pulp rich in Macrophages.

    48. Circulation of Naïve and Activated/Memory T Lymphocytes

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