1 / 11

Understanding and Managing Insulin Resistance Progression to Diabetes and Hypertension

Explore the stages of insulin resistance progression, treatment recommendations, and managing inflammation markers like hs-CRP for better health outcomes. Learn about risk factors, early intervention strategies, and lifestyle modifications.

emartins
Download Presentation

Understanding and Managing Insulin Resistance Progression to Diabetes and Hypertension

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Insulin Resistance Progression to Diabetes

  2. Hypertension: BP >140/90 • Dyslipidemia: • TG >150 mg/dL (1.7 mmol.L) • HDL-C <35 mg/dL (0.9 mmol/L) • Obesity (central): BMI >30 kg/M2 • Waist girth > 94 cm (37 inch) • Waist/Hip ratio > 0.9 • Impaired Glucose Handling: IR, IGT or DM • FPG >110 mg/dL (6.1 mmol/L) • 2 hr. PG >200 mg/dL (11.1 mmol/L)

  3. Inflammation

  4. Stage 1 – Early Insulin Resistance

  5. Treatment recommendations for Stage 1 Stage 1 – Early Insulin Resistance

  6. Graph represents patient's stage of pre-diabetes. Stage 2 – Elevated Insulin

  7. Treatment recommendations for stage 2

  8. Graph represents patient's stage of pre-diabetes. Stage 3: Beta-Cell Dysfunction

  9. Treatment recommendations for stage 3

  10. High hs-CRP associated with: • Chronic inflammatory state. • Insulin resistance (independent of obesity) and increased risk of type 2 diabetes. • Hypertension, metabolic syndrome, and aging. • Increased risk of coronary artery disease, peripheral artery disease, and increased risk of cardiac death in individuals with previous heart attack. Inflammation MarkersHigh-sensitivity C-Reactive Protein (hs-CRP)

  11. Treatment Options to reduce hs- CRP:

More Related