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The developing human. 陳建榮. http://web.nchu.edu.tw/pweb/users/chenjr/. 教科書及參考資料: 1. The Developing Human (7TH, 2003, by Keith L. Moore & T. V. N. Persaud) 2. Langman’s medical embryology (9th, 2004, by T.W. Sadler) 3. http://embryology.med.unsw.edu.au/ 4. 講義. 評量方式: 期中考 (45%)
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The developing human 陳建榮 http://web.nchu.edu.tw/pweb/users/chenjr/
教科書及參考資料: 1. The Developing Human (7TH, 2003, by Keith L. Moore & T. V. N. Persaud) 2. Langman’s medical embryology (9th, 2004, by T.W. Sadler) 3. http://embryology.med.unsw.edu.au/ 4. 講義 評量方式: 期中考 (45%) 期末考 (45%) 平時成積 (10%)
Embryology • Human development is a continuous process that begins when a zygote is formed • Development does not stop at birth
Developmental Periods • Gametogenesis • Spermatogenesis • Oogenesis • Prenatal period (Fertilization) • Embryo: Zygote • Cleavage • Implantation • Gastrulation • Organogenesis • Fetus • Postnatal period • Neonate (<1 month) • Infancy (< 1 yr) • Childhood • Puberty (13 yr – 16 yr) • Adulthood
LNMP (last normal menstrual period) 胎齡: fetus embryo Trimester
測量胚胎大小: 最大長 頂臀長 頂踵長
Carnegie stagesare a system used by embryologists to describe the apparent maturity of embryos 1st trimester
Formation of Bilaminar Embryonic Disc Stage 5: 7th –12th day full implantation 2nd week
Stages 6-9: Day 13-21 Somites 3rd week
Stages 10-17 4th to 6th week
7 8 • Embryo(end of the 8th week) - all major structures are present • Fetus(after 8th week)
Genetics and Molecular biology are applied in human development • Ian Wilmut [1997] Somatic cell nuclear transfer – Dolly lamb • Embryonic stem cell
Stem cell Embryonic stem cell Morula Blastocyt