Nanosafety assessment methodology. Kaarle Hämeri Professor in Aerosol physics University of Helsinki Finnish Institute for Occupational Health. Take home -message. Aerosol particles have wide range of sizes and other properties
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Professor in Aerosolphysics
University of Helsinki
Finnish Institute for Occupational Health
TSI CPC model 3776
TSI CPC model 3007
Shape (Shape factor χ)
Mass concentration (μg/m3)
Number concentration (1/cm3)
Surface area (m2/m3)
Size distribution (number, surface area, mass)Aerosol particle properties
and the physical principle used
Qaerosol + QclassifiedDifferential Mobility Analysis
Particle size classes 1 nm – 100 µm
-> Football hall vs. globe
Or spoonful vs. km3 (1012 l)
Need for investigations of:
-several properties, several intruments and methods...
Consepts of nanoparticles (NP) (~1 nm <Dp< 100 nm):
Importance of the size distribution!
Nanomaterials (CNTs, agglomerates, …)
Lung deposition curves defined by International Comission on Radiological Protection
Suburban, mechanical ventilation
Urban, high mech. ventilation
Urban, low mech. ventilation
time series during the
Particlesfromburning of impurities
Level of respiratoryprotectionthatcanbeexpected to beachieved in the workplaceby 95% of adequatelytrained and supervisedwearersusing a properlyfunctioning and correctlyfittedrespiratoryprotectivedevice (Europeanstandard: EN529).
APF = 20
Schematic of FilterEfficiency vs. ParticleSize
APF = 200
Massconcentration is notpropermetric in exposureassessment for synthesizedNPs.