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volume homeostasis - PowerPoint PPT Presentation


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Renal Na excretion. Na is the major extracellular cationIntracellular [Na] is maintained at low levels (10 - 20 mM) by the Na,K-ATPaseThe [Na] in the extracellular fluid is maintained constant (140 mM). Therefore, the amount of Na present in the extracellular space (Na content) is the major determinant of the extracellular fluid volume (ECFV).increased Na content -----> increased ECFVdecreased Na content -----> decreased ECFV.

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