INTRODUCTION to PHARMACOLOGY. MEDICINE IN ANCIENT EGYPT. EARLY MESOPOTAMIAN CULTURE. PRIMITIVE AMERICAN INDIAN CULTURES. HIPPOCRATES: MEDICINE BECAME A SCIENCE. TERMS to REMEMBER. DRUG PHARMACOLOGY CLINICAL PHARMACOLOGY pharmacokinetics pharmacodynamics PHARMACOTHERAPEUTICS.
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PRIMITIVE AMERICAN INDIAN CULTURES
4 – 8 HRS SHORT HALF-LIFE
24 HRS LONG HALF-LIFE
THE TIME IT TAKES FOR HALF OF THE DRUG CONCENTRATION TO BE ELIMINATED
STEADY STATEdrug intake = amount excreted……
therefore!!...........serum conc. = therapeutic effect
By Emma Reid, February 25, 2000People who suffer from epilepsy, stroke or other brain traumas often have very high levels of brain activity during an episode or an attack. This high level of activity can cause an unpleasant chain of events leading to brain cell death. Researchers from the Jefferson Medical College in Philadelphia, PA have developed a way to reduce the 'high activity' response in rats using an important oral vaccine. The oral vaccine stimulates the production of antibodies which block an important receptor in the brain , preventing glutamate from binding to receptor sites (like on the lower cell in the image and sending messages along the chain.
Always remember to check the name (trade and generic), dosage form, strength, and indication (reason the drug is being prescribed) before giving it to a patient. An error may have been made before you received the order!
A complete list of more than 800 sound-alike trade names can be found on the
United States Pharmacopeia (USP).
John G is receiving an experimental drug (AK22) for the treatment of actinic keratosis, a skin lesion that, if untreated, will progress to a skin cancer called squamous cell carcinoma. The drug is delivered in a cream applied to the lesions twice a day.
After 3 weeks, John’s lesions have fewer scales and are less red. Some have disappeared. The science of what AK22 does tothe body is called: