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Explore treatment options for mild to moderate depression in adult women, focusing on St. John's Wort as an alternative therapy. This review compares the efficacy of St. John's Wort vs. placebo in reducing depression episode duration. Learn how to form a clinical question using the PICO framework and conduct a search query to access relevant information. Discover the potential benefits of St. John's Wort as a natural remedy for depression management.
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Module 2Forming a Clinical Question and Subsequent Search Query
Scenario • A 48 year-old female with mild to moderate depression. Has no time for additional exercise and does not want to take any prescription drugs.
Treatment Options • Prescription antidepressant drugs • St John’s Wort • Exercise
Focus on the Foreground P adult, female, mild to moderate depression I St Johns Wort C Placebo / no comparison O reduce duration of symptoms In adults (female) with mild to moderate depression, does St Johns Wortreduce the duration of depression episodes?
PICO-TT • T – type of scenario = therapy • T – type of trial = RCTs
PICO Search Query P adult female, depression I st johns wort C placebo O reduce duration of symptoms P adult female depression affective disorder I st johns wort st john’s wort MeSH via PubMed
PICO Search Query (depression OR depressive disorder OR mood disorder OR affective disorder) AND (st john’s wortORst johns wortORhypericum) Place an “OR” between synonyms of the same concept and surround concept terms with parentheses Place an “AND” between concepts