Mutations
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mutations. Defined. Sometimes, mistakes are made while copying DNA. If those mistakes are not repaired, it leads to a… Mutation An error in DNA. 2 Kinds of Mutations. Point Mutation An error occurring at a single point in the DNA One base is changed to different base EX:

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Presentation Transcript

Defined
Defined

  • Sometimes, mistakes are made while copying DNA. If those mistakes are not repaired, it leads to a…

  • Mutation

    • An error in DNA


2 kinds of mutations
2 Kinds of Mutations

  • Point Mutation

    • An error occurring at a single point in the DNA

    • One base is changed to different base

  • EX:

    • Original strand:

      TAC GGA ATT CGC ATC CCC

    • Copied strand:

      TAC GGA ATT CTC ATC CCC


2 kinds of mutations1
2 Kinds of Mutations

  • Frameshift Mutation

    • An error causing a shift in the DNA sequence

    • Addition of a new base or deletion of a base in DNA

  • EX:

    • Original: TAG CCT AAC ATG GCA TAT

    • Mutated: TAG CCT GAA CAT GGC ATA T

    • Original: TAG CCT AAC ATG GCA TAT

    • Mutated: TAG CCA ACA TGG CAT AT


Results
Results

  • A point mutation or a frameshift mutation can have a range of results on our proteins formed during protein synthesis…

  • Here’s how to classify the types of results:


Results1
Results

  • Silent Mutation

    • The error in DNA causes no difference in the protein formed

  • Missense Mutation

    • The error in DNA causes a change in the protein formed, such as one incorrect amino acid

  • Nonsense Mutation

    • The error in DNA causes a MAJOR problem in the protein formed, such as the absence of a start codon, or an early stop codon


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