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George Twaddle Program Chair for Biotechnology Ivy Tech Community College of Indiana – South Bend PowerPoint Presentation
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George Twaddle Program Chair for Biotechnology Ivy Tech Community College of Indiana – South Bend
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  1. The Ultimate Inquiry Lessons from the Genetically Engineered Machine Competition George Twaddle Program Chair for Biotechnology Ivy Tech Community College of Indiana – South Bend

  2. How to get students interested in STEM careers?

  3. Gibson Assembly Song Team Cambridge iGEM Competition 2010

  4. Synthetic Biology • New area of biological research • Combines science and engineering • Design and construction of artificial • biological functions and systems

  5. Genetic Code is UNIVERSAL -Discovery of “restrction enzymes” allows us to cut and build recombinant DNA and to express new genetic combinations..

  6. The New Generation of “Micro” Computers?

  7. A BIT O’ iGEM HISTORY Began in January of 2003 Independent Activities Period (IAP) at MIT (The students designed biological systems to make cells blink). • 5 teams in 2004 • 13 teams in 2005 • 32 teams in 2006 • 54 teams in 2007 • 84 teams in 2008 • 112 teams in 2009 • 130 teams in 2010

  8. 2011.igem.org The International Genetically Engineered Machine competition (iGEM) is the premiere undergraduate Synthetic Biology competition. Student teams are given a kit of biological parts at the beginning of the summer from the Registry of Standard Biological Parts. Working at their own schools over the summer, they use these parts and new parts of their own design to build biological systems and operate them in living cells. This project design and competition format is an exceptionally motivating and effective teaching method.

  9. What’s an “iGEM?” • An undergraduate synthetic biology annual competition • Kit of biological parts at the beginning of the summer. • Build biological systems out of the parts or new parts that they create and operate them in living cells • Come to a “Jamboree” at the end to show-off and see who is most innovative.

  10. iGEM MIT Paternity Randy Rettberg iGEM Competition “Open WetWare” Tom Knight “BioBrick” inventor GinkoBioWorks Drew Endy BioBricks Foundation

  11. THE “BIOBRICK” A standard for interchangeable parts. For building complex biological systems in cells Standards achieved through unique “prefix” and “suffix” restriction sites.

  12. A3 Assembly of BioBricks to Form a “Device”

  13. Student created wiki part page

  14. Elements of the Competition Poster presentation Team wiki and Team Parts Pages Platform presentation

  15. Medals and Awards Gold Silver Bronze

  16. Inquiry-Based Learning “A student-centered / teacher-guided instructional approach that Engages students in investigating Real World Questions that they choose within a broad thematic framework. Students acquire and analyze information, develop and support propositions, provide solutions, and design technology that demonstrate their thinking and make their learning visible.” Northeastern Illinois University Dept. of Eduction

  17. What’s your Problem? Food? Energy? Environment? Health and Medicine? Industrial & Biomanufacturing? Software? Process Advance?

  18. Team Groningen, Netherlands 2009

  19. Team British Columbia, Canada 2009

  20. EPFL Luasanne, Switzerland 2010

  21. University of Slovenia 2010

  22. Ivy Tech Community College of Indiana Bronze Medal Team

  23. Education Community Industry BioFuture: Partnerships in BiotechnologyPartnerships in the Future Media Local Gov Foundations State Gov. Federal Gov. Associate of Science or Associate of Applied Science In BIOTECHNOLOGY Bloomington Lafayette Lawrence South Bend Terra Haute SKILLS AND KNOWLEDGE STANDARDS FOR ASSOCIATE DEGREE IN BIOTECHNOLOGY PROGRAMS IN INDIANA Created by: Alisa Wright, Baxter Pharmaceutical Solutions Gary Bormett, Dow AgroSciences LCC Jose Hanquier, Robert MacKay, Roberta Talmage, Eli Lilly and Company Wade Lange, Indiana Health Industry Forum Andy Cothrel, Roche Diagnostics Corp. June 30, 2003

  24. iGEM High School Division 2010 • Greenfield Central High School • Warren Central High School • “The DNA Architects of South Bend – Mishawaka (Marian, Penn and Riley High Schools

  25. Illustration credits Line of students: www.LowestPricedTrafficSchool.com Gibson Assembly Song: www.cambrigeigem.org Synthetic biology figures: “Biology” Campbell and Reece. Pearson, Benjamin-Cummings Publishers (2010) www.masteringbiology.com Bacteria: Ministry of Public Works, Canada www.blog.poolcenter.com iGEM team photos, wiki screen shots, etc. 2011.igem.org